Pasteur
- The Institut Pasteur
- History
- Alphonse Laveran (1845-1922)
- André Lwoff (1902-1994)
- Charles Nicolle (1866-1936)
- Daniel Bovet (1907-1992)
- François Jacob (1920-2013)
- Françoise Barré-Sinoussi, born in 1947
- Ilya Mechnikov, Elie Metchnikoff in French (1845-1916)
- Jacques Monod (1910-1976)
- Jules Bordet (1870-1961)
- Luc Montagnier, born in 1932
- The early years 1847-1862
- The final years
- The middle years 1862-1877
- The Institut in numbers
- The Institut Pasteur throughout the world
- News
- "We have achieved some of our dreams to advance science in Africa"
- A 4-year research group soon to be created in China
- A Global mapping of mosquitoes vectors of Zika virus
- A Pasteur International Joint Unit to counteract the evolution of viruses
- A new survival mechanism of the tubercle bacillus unveiled
- A project to strengthen National Ethics Committees in Francophone Africa
- Aedes aegypti mosquitoes’ gut microbiota is environmentally determined
- Agnès Buzyn, Minister of Solidarity and Health visited the vectopole of the Institut Pasteur de la Guyane
- Anticipating and reacting quickly to outbreaks: a consortium won the Galien MedStartUp award
- Avian flu: Cambodian markets under heavy surveillance
- Can we make human plague history?
- Claude Flamand : predicting epidemics with satellite images
- Dr Amy Kristine Bei to head a new 4-year research group on malaria in Dakar
- Dr. Didier Koumavi Ekouevi Wins the 2018 Dedonder-Clayton Award
- Dr. Richard Njouom laureate of the Dedonder-Clayton Prize 2017
- Elisabeth Carniel appointed Director General of the Pasteur Center in Cameroon
- Elliot Rakotomanana, an anthropologist against malnutrition in Madagascar
- Five young researchers from the Institut Pasteur International Network attended the 2017 PhD students' ceremony
- Five young researchers from the Institut Pasteur International Network, at the 2018 doctoral ceremony
- Food contamination in Cambodia contributing to the burden of antibiotic resistance
- Four young researchers from the Institut Pasteur International Network present at the 2019 PhD Student Ceremony
- Halima Maïnassara: from field investigator to director of CERMES in Niger
- Hepatitis B: to better identify patients eligible for treatment in Africa
- High incidence of neonatal infections in Madagascar
- In remembrance of Dr François Rouet
- In remembrance of Dr Vu Thi Que Huong
- Institut Pasteur and Hamad Bin Khalifa University will collaborate on training in the areas of genome research , precision medecine and disease prevention
- Institut Pasteur de Dakar: The 4-years research group Biostatistics, Bioinformatics and Modeling integrates the H3ABioNet pan-African network for bioinformatics
- International workshop in Iran to strengthen surveillance and control of rabies
- Malaria: Plasmodium falciparum protein MSP4 is a potential target for a vaccine
- Mamadou Aliou Barry, a lookout against epidemics in Senegal
- MediLabSecure: 4 years of health security improvement against vector-borne diseases in the Mediterranenan and Black Sea Regions
- Medical entomology for surveilling vector-borne diseases explained in motion design
- Meriem Ben Ali : a better diagnosis for immune deficiencies in Tunisia
- Moritoshi Iwagami Wins the 2018 Robert Deschiens Prize
- Multicentric research has identify Leptospira bacteria circulating in Uruguay
- National Health Laboratory Project launched
- New Pasteur-USP Scientific Platform in Brazil to tackle neurological disorders with a one health approach
- Pasteur International Network Association supported 3 statements at World Health Assembly 2018
- Pertussis : progress but lack of surveillance
- Rabies: a shorter, cheaper vaccination schedule following a suspected rabid dog bite
- Renewal of the status of the Pasteur International Network Association as a "non-State actor in official relationship" with WHO
- Report on the 49th Institut Pasteur International Network Directors' Council in Abidjan
- Researchers at the Institut Pasteur in French Guiana describe the persistence of Zika virus in semen
- Researchers from the Institut Pasteur in Iran and French Guiana Win the 2018 "Pasteur Talent" Award
- Roka village in Cambodia: a history of iatrogenic HIV infection
- Roman Thibeaux’s joust with bacterial armor
- Six institutions members of the Institut Pasteur international network engaged in an international coalition against epidemics in Africa
- Spencer Shorte appointed Chief Scientific Officer to Institut Pasteur Korea
- Strong increase in antibiotic resistance in Cambodia
- Successful second international medical entomology course in Vientiane, Laos
- The 2019 "Prince Albert II of Monaco - Institut Pasteur" Prize is awarded to Joacim Rocklöv
- The 49th Institut Pasteur International Network Directors council will be held in Abidjan
- The Chinese Ambassador to France visits the Institut Pasteur
- The FioCruz-Pasteur-USP tripartite agreement is bearing fruits
- The Institut Pasteur International Network enters the GloPID-R alliance
- The Institut Pasteur International Network pays tribute to Professor Ogobara Doumbo
- The Institut Pasteur de Guinée opens its first laboratory in Conakry
- The Institut Pasteur de Nouvelle-Calédonie describes 12 new species of leptospires and pays tribute to Pasteurians
- The Institut Pasteur in French Guiana confirms a case of yellow fever
- The Institut Pasteur launches a Scientific Platform in the university of São Paulo Research and Innovation Center
- The first "Pasteur International Talent" reward two young scientists of the Institut Pasteur in Guadeloupe and Montevideo
- The medical entomology course at the Institut Pasteur celebrates its 30th anniversary
- Three projects from the Institut Pasteur in Dakar and Madagascar selected for funding by AESA’s Grand Challenge Africa
- Twelve new species of Leptospira discovered in New Caledonian soils
- Vaccines: a life insurance for humankind
- Viral hepatitis: the challenge of communication in Africa
- Wolbachia, bacteria to combat dengue
- Zika virus in the Pacific : the influence of the geographical context on an outbreak’s emergence
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- Reports
- AIDS: progress and fresh hope
- Alzheimer's and Parkinson's – the current state of research
- Alzheimer’s disease: towards new diagnostic and therapeutic tracks
- Antibiotics: when bacteria fight back
- At the heart of the brain
- Autism – following the genetic lead
- Autism: a unique event at the Institut Pasteur
- Autoimmune diseases: When our own defenses turn against us
- Challenging the aging process
- Coronavirus SARS-CoV-2: A look back at three months of mobilisation against an emerging disease (COVID-19)
- Ebola 2013-2016: lessons learned and how to respond to new epidemics
- Ebola, plague, cholera, SARS… Emerging pathogens, an unpredictable threat
- French Bioethics Law: an original participatory approach for the National Bioethics Consultation
- From Molecular Biology to Stem Cells
- How big data is revolutionizing health research
- Human evolutionary genetics: the benefits of genetic diversity
- Infection-related cancer
- Joining forces against the plague in Madagascar
- Keeping a close eye on influenza
- Managing outbreaks more effectively
- Meningitis – the Institut Pasteur pledges its support to the "Ensemble contre les méningites" association
- Microscopes – observe the living to fight disease
- New weapons to fight bacteria
- Repairing the brain
- Salmonella outbreak: Institut Pasteur raises the alarm
- Southeast Asia faces the rise of emerging diseases
- Tackling allergies
- The Insitut Pasteur is addressing the major scientific and health issues facing the world today
- The Institut Pasteur in 2018: A legacy of excellence
- The Research Journal : the most read articles in 2017!
- The Research Journal: 2018's most read articles!
- Understanding autism
- Yellow fever, the story of a re-emerging virus
- “The Geopolitics of the Mosquito” - Go further with our experts!
- News
- "N-terminomics" reveals how Listeria bacteria detect and react to stress
- "Pasteur, the experimenter" – the must-see exhibition!
- "Pasteur, the microbe legacy" lecture cycle
- 130 years ago, the Institut Pasteur opened its doors for the first time
- 130 years ago, the Institut Pasteur was under construction
- 2016 yellow fever outbreak in Brazil: tiger mosquitoes are also capable of transmitting the virus
- 2018 Activity Report for the Pasteur Microbes and Health Carnot Institute
- A Task Force for responding to outbreaks such as Zika
- A biological interface for prostheses: the futuristic project of the 2018 Pasteur iGEM team
- A breakthrough in understanding the innate immune response activated by dengue and Zika viruses
- A comprehensive analysis of midbodies, bridges between dividing cells
- A debate on sepsis at the Institut Pasteur
- A fast likelihood method to reconstruct and visualize ancestral scenarios
- A high level international conference on microbes and vectors resistance
- A link between the microbiota and the severity of tuberculosis
- A microbial virus from extreme environments opens doors to new therapeutical strategies
- A modular gene enhancer plays a role in leukemia
- A new 800 MHz nuclear magnetic resonance instrument at the Institut Pasteur
- A new Listeria species from Costa Rica identified
- A new approach for deciphering complex immune responses
- A new biochemical pathway implicated in the proliferation of cancer cells
- A new biotechnology tool to tackle antibiotic resistance
- A new breakthrough in limb development
- A new call for students by the PPU International doctoral program
- A new mathematical approach to measure the reliability of phylogenetic trees in the big data era
- A new mechanism used by group B Streptococcus to evade the host immune system
- A new signaling pathway in the proliferation of cardiac cells
- A new step in understanding the mechanisms that control cilia length
- A research ethics committee at the Institut Pasteur since 2009
- A strategy for attenuating a virus by modifying its evolutionary potential
- A theory to link genes with social awareness
- A tobacco-dependence gene responsible for alcohol dependence
- AIDS: NK cells in the innate immune system control viral replication in the lymph nodes
- Adapt to survive: the intestinal microbiota promotes viral persistence
- Aimee Wessel and Raphaël Tomasi win the i-Lab award for their MultiScreen project
- Airborne Bacterial Volatiles stimulate Fungal Growth
- Alexandre Yersin, the man who discovered the bacterium responsible for the plague
- An innovative tool to study psychiatric or infectious diseases
- An international conference on Emerging Infections & Pandemic Risk
- An update on Ebola in the Democratic Republic of the Congo with Arnaud Fontanet, an expert at the Institut Pasteur
- An update on the Institut Pasteur's work on CRISPR-CAS9
- Artificial intelligence speeds up high-resolution microscopy
- Artificial intelligence: a new platform for the biomedical community
- Artificial intelligence: deep learning is blazing ahead
- At the Institut Pasteur, a new insectarium for arbovirus mosquito vectors
- Autism: a virtual avatar to make precision medicine
- Award for the DIVA platform at the Start-Ulm competition
- Bacterial Achilles' heel discovered providing a new target for antimicrobial treatments
- Biotechnology: DNA polymerases that can replicate DNA without a primer!
- Blood test: a potential new tool for controlling infections
- Book release: “Institut Pasteur: Today's Research, Tomorrow's Medicine”
- COVID-19 - The Bioinformatics and Biostatistics Hub on the front line
- COVID-19, chronicle of an expected pandemic / Exiting lockdown or the sum total of all dangers
- COVID-19: the latest on the epidemic situation and why caution is still needed
- Catherine Rougeot and the discovery of a new painkiller molecule
- Cellular therapy: identification of circulating human Innate Lymphoid Cell Precursors
- Ceremony for the 2019 Pasteur Vallery-Radot Prize (awarded by the BnF)
- Chaos in ageing skeletal muscle stem cells
- Chikungunya spreads in and around homes with women at highest risk
- Chikungunya: the specific interactions between the genotypes of mosquitoes and viruses have influenced Ae. albopictus vector competence for the virus
- Christine Petit and her discoveries concerning early-onset hearing loss
- Christine Petit receives the ARO Award of Merit for her work to elucidate the mechanisms of hearing and deafness
- Contact with monkeys and apes puts populations at risk
- Covid-19: a study in children with hyper-inflammatory syndrome related to Kawasaki disease
- Culex mosquitoes do not transmit Zika virus
- DIVA: Virtual reality for complex image analysis
- DNA viruses infiltrate 3D cellular genome organization and preferentially contact active chromatin
- Daniel Iffla-Osiris, a great 19th-century philanthropist and the Institut Pasteur's most generous donor
- Decades-long trends, rather than flawed vaccine, best explain resurgent whooping cough
- Deep-learning to improve super-resolution microscopy methods
- Demystifying immunity in the bladder
- Depression: the key role of neuroinflammation
- Destroying Helicobacter pylori by disrupting synthesis of its cell wall!
- Discovery of a mechanism responsible for chronic inflammation in patients suffering from multiple sclerosis
- Discovery of a restriction factor for hepatitis B virus
- Discovery of new strains of the HTLV-4 virus in hunters bitten by gorillas in Gabon
- Discovery of the mechanism used to coordinate replication of the two Vibrio cholerae chromosomes
- Distinguishing resistence from resilience to prolong antibiotic potency
- Division – a key moment in establishing cell polarity
- Drastic reduction of exposure to malaria in Senegal
- EDF Group Foundation supports the Institut Pasteur and the DIVA project
- ERC grants: scientific excellence supported by Europe
- Ebola: the answers to your questions in our disease sheet
- Economist Jim O’Neill, and other experts, discuss Antimicrobial Resistance at the Institut Pasteur
- Effect of the seasons on pneumococcal infections
- Efficacy of cancer treatment: two bacteria in the microbiota identified
- Esrrb transcription factor plays a key role in maintaining stem cell identity even after countless divisions
- Establishment of the Hearing Institute, a new Institut Pasteur center: scientific experts within the field of hearing brought together for a high-level international meeting
- Exhibition in honor of Jules Bordet at the Université libre de Bruxelles
- Exhibition: the amazing achievements of "Pasteur, the experimenter"!
- Existing drugs can prevent SARS-CoV-2 from hijacking cells
- Explanation and advice following the case of rabies in France
- First statement from the Pasteur International Network association to the World Health Assembly
- First stone laid for the Institut Pasteur in Guinea
- Following maternal transmission, group B strep mutates to sicken infants
- Fondation IPSEN supports new MOOCs at the Institut Pasteur
- Foreign travel – a tonic for the health?
- Françoise Barré-Sinoussi and her research on the HIV-1 virus
- Françoise Barré-Sinoussi elected as a member of the US National Academy of Medicine
- Frédéric Tangy, expert from the Institut Pasteur, talks about vaccines of today and tomorrow
- Genetic cause of difference in sexual development uncovered
- Genomics study in Africa: demographic history and deleterious mutations
- Gut microbiota: surprising interactions between pathogenic and commensal bacteria
- HIV-1: revealed during the nuclear entry step. Direct visualization in living cells using “HIV-1 ANCHOR” technology
- Health and environment: Institut Pasteur and AFD commit to a new program
- Hepatitis B may infect twice more African babies than HIV
- Hepatitis B: natural controllers shed light on immunity mechanisms
- High-level microscopy unveils bacteria’s adaptation mechanisms
- How Chlamydia trachomatis hijacks energy stores from its host
- How Helicobacter pylori survives gastric acidity
- How Listeria monocytogenes blocks intestinal villus invasion
- How does Legionella pneumophila, the bacterium causing legionellosis, use the host cell machinery to its own advantage?
- How dying cells regulate immunity
- How human pathogens may emerge from the environment
- How investigating the population biology of Listeria is ushering in a new era in listeriosis surveillance
- How the influenza virus achieves efficient viral RNA replication
- Human contact plays big role in spread of some hospital infections, but not others
- Icypro, an advanced bioimage analysis platform for health technology professionals
- Identification of a new bacterial defense system against phages
- IgG antibodies activate blood platelets and contribute to the severity of anaphylaxis
- Immature heart cells persist in the adult heart and react to infarction
- Immune cells fighting blood cancer visualized for the first time
- In France, Aedes albopictus better transmits the African "Zika" than the Asian one
- In the Pasteur library with Hervé Di Rosa
- Inauguration of the Hearing Institute, an Institut Pasteur center
- Infant nutrition: an overly rich diet may increase susceptibility to inflammatory diseases
- Infravec2 new insect vector research tools: no-cost resources for scientists fighting mosquito-transmitted diseases
- Innate immune responses – redefining how innate lymphoid cells develop
- Insect vectors: a mosquito capable of limiting viral infection
- Insecticide resistance genes affect vector competence for West Nile virus
- Institut Pasteur in Guinea: One Health training to strengthen local expertise
- Institut Pasteur scientists during the Great War
- Institut Pasteur team identifies a key protein linked to ageing
- International Women's Day 2019
- Interview with Prof. Jean-François Delfraissy about French National Bioethics Consultation, a forum for the public and the research community
- Just the two of us: Holding hands can ease pain, sync brainwaves
- Key cellular factors for chikungunya virus replication identified
- Lassa fever: vaccine set to be trialed
- Launch of the recruitment process for the Director of the Institut Pasteur
- Leishmaniasis: epigenetic mechanisms implicated in infection
- Listeriosis: food type determines Listeria monocytogenes virulence
- Liver cancer: the Peruvian exception
- Long-awaited determination of the 3D structure of a human transporter
- Low competence of Aedes mosquitoes for Zika virus transmission
- LuLISA project, bioluminescence as a tool for human diagnostics, from allergy to Covid19
- Lyme disease – chipmunks may affect tick infection but the risk of transmission is more complex
- Lyme disease: a study on the speed of transmission by infected ticks
- Mechanism of activation of a major toxin involved in whooping cough
- Meningitis: analysis of the long-term protection of the MenAfriVac vaccine
- Meningococcal infection: bacterial aggregates form a thick honey-like liquid that flows through blood vessels
- Microbiota and solid food introduction: interview with Gérard Eberl
- Modeling to monitor and anticipate the Zika outbreak in Martinique
- Monkeypox: the epidemic potential will continue increasing, with diminishing herd immunity against viruses responsible for smallpox
- MosKeyTool: a free and interactive tool to identify mosquitoes of the Euro-Mediterranean region
- Mosquitoes and viruses by Sarah Merkling
- Multiscale structure of the Escherichia coli genome
- Natural molecules to stimulate human antimicrobial defenses
- Neurobiologist Jean-Pierre Changeux tells us the story of the nicotinic acetylcholine receptor
- Neurodegenerative diseases: recycling mechanisms open up new avenues for therapy
- Neurodevelopmental disorders: a daily practical guide by InovAND to help families deal with the difficulties of lockdown
- Neurological impact of the Zika virus finally exposed
- New Fellowships have been announced to enhance the next generation of global health leaders
- New insight into body's response to killer fungus
- Novel coronavirus (SARS-CoV-2): what we know about the disease
- Novel neurotropic arbovirus identified in France: the Umbre virus
- Olivier Gascuel: Inria – French Académie des sciences Grand Prize
- Omics: Biology in the digital age at the Institut Pasteur
- Parkinson's: new discoveries about nanotubes, transporters of toxic proteins
- Pasteur iGEM 2019: simplified diagnosis of bacterial infections
- Pasteur's Nephew – Or the Adventurous Life of Adrien Loir, Scholar and Globe-Trotter
- Pasteurdon 2019: Graffitti artists meet scientists and create stunning lab coats
- Phage therapy effective in Crohn's disease
- Phagotherapy: a support for the work on bacteriophages of a Franco-American team (Institut Pasteur and Georgia Tech)
- Phylogenetic analysis of SARS-CoV-2: strengths, limitations and over-interpretations
- Plague outbreak: advice for travelers to Madagascar
- Progress in the understanding of the mechanisms of genetic diversification in a major fungal pathogen of humans, Candida albicans
- Proof-of-concept study reveals feasibility of eliminating rabies in Africa
- Quiescent cells also mutate!
- Rabies in Cambodia
- Rabies: new prophylactic and therapeutic avenues
- Regulation of metabolic pathways: lessons from an intracellular bacterium
- Regulation of muscle stem cells in their niche: juggling external and internal cues
- Report on the 2018 Pasteur Vallery-Radot Prize
- Réseau Bactériophages France receives the François Sommer Foundation scientific prize
- S3ODEON 2019 – Institut Pasteur partner to an event linking science and society
- SODA, a new analysis tool for fluorescence imaging
- Severe inflammation: clues towards a therapeutic approach using immune memory
- Sex-based differences influence chronicity in urinary tract infections
- Shedding light on almost indestructible archaeal pili
- Shedding light on the burden of dengue in Bangladesh
- Sign up for the upcoming Institut Pasteur MOOCs
- Sleeping sickness: one step further in improving diagnosis
- Small intestine regulates immune surveillance of colorectal cancer during chemotherapy treatment
- Staphylococcus aureus: a new mechanism involved in virulence and antibiotic resistance
- Study reveals conditions for the onset of severe forms of COVID-19
- Studying synaptic protein assemblies helps us understand the nature of communication between neurons
- Success of the 2019 Z Event in aid of the Institut Pasteur
- Summer University dedicated to the creation of life sciences company
- Support for government policy for the prevention of infectious diseases
- Table salt to diagnose malaria
- Ten years ago, Françoise Barré-Sinoussi and Luc Montagnier won the Nobel Prize in Medicine
- Thank you, Simone Veil!
- The 2016 Pasteur Vallery-Radot Prize
- The 2017 Pasteur iGEM team – a purifying and recycling device
- The 2018 Institut Pasteur Annual Report is available
- The BTP PLUS Foundation is funding a research project to fight asbestos cancer
- The Ebola virus adapted to better infect humans during the 2013-2016 epidemic
- The French Parliamentary Office of Science and Technology pays a visit to the Institut Pasteur
- The ISG15 protein plays a key role in fighting bacterial infections
- The Institut Pasteur in Côte d'Ivoire diagnoses a dengue epidemic in Abidjan
- The Institut Pasteur wishes you a happy new year 2020
- The Institut Pasteur: a leader in the fight against antibiotic resistance
- The Musée Pasteur featured in book of Parisian hidden gems
- The Zika virus modifies the morphology of the cells and makes them implode
- The book “Institut Pasteur: Today's Research, Tomorrow's Medicine” available in US bookstores
- The documentary Unseen Enemy in streaming on ARTE.TV
- The factors that most affect our immune system
- The first "3D" metagenomics experiment on a complex natural microbiome
- The first case of prolonged remission in an HIV-infected child – an interview with Asier Saez-Cirion
- The hidden population of multidrug-resistant Klebsiella bacteria colonizing the human digestive tract
- The issues of epidemiology with Arnaud Fontanet
- The long history of medical entomology
- The molecular crossbow: a vital weapon in the bacterial arsenal
- The shape of the heart as explained by Audrey Desgrange
- The structure and assembly of the Enterohemorrhagic Escherichia coli type 4 pilus deciphered
- The tiger mosquito returns to France: 51 départements on red alert
- The web meets genomics: a DNA search engine for microbes
- Third type of membrane envelope in a hyperthermophilic virus
- This week, France Culture's flagship documentary series explores the life and work of Louis Pasteur
- Tiger mosquito in France: 58 départements on red alert
- Tiger mosquitoes: heightened surveillance in France, from May to November 2018
- Titan Krios (TM): inauguration of the world’s most powerful microscope at the Institut Pasteur
- Tribute to the Institut Pasteur in Genes & Immunity
- Tumor cells eliminating their neighbors using a newly discovered mechanism
- Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes
- Two major types of rabies that evolved in different ways
- Unmasking an ancestral mechanism of integrons — key players in antibiotic resistance
- Unseen Enemy, a film about our vulnerability to global epidemics
- Usher syndrome type III: cochlear gene therapy preserves hair cell synaptic transmission to the auditory neurons
- Using medicinal chemistry to improve diagnostic methods
- Viral sequence integrated in mosquito genome controls infection by related virus
- What is the "tiger mosquito" (Aedes albopictus)?
- When Listeria attacks the intestinal microbiota
- When the structure of Tunneling nanotubes (TNTs) challenges the very concept of cell
- Whooping cough: elucidation of a critical stage in the action of the CyaA toxin
- Why some patients develop resistance to new class of anti-cancer drugs
- Why vaccines are essential
- Yellow fever: using modeling to optimize the use of vaccine stocks
- Yersinia – a novel genomic tool for identifying strains
- Zika: two indigenous cases for the first time in mainland France
- i-Lab 2020 competition: two winners from the Institut Pasteur, one awarded a Grand Prix
- Events
- Portraits
- 3D research according to Albane Imbert, an engineer at the Institut Pasteur
- An Epidemiologist Faces Ebola in The Democratic Republic of the Congo
- Anna-Bella Failloux, an all-terrain entomologist!
- Diego Cordero Cervantes, globe-trotting researcher
- Fabrice Chrétien, from stethoscope to microscope
- Fani Koukouli: A young researcher's odyssey to the inner depths of the brain
- For Asier Sáez-Cirión, research is an incurable passion
- Humans, animals and their environment, an investigation by Victor Narat
- Jean-Philippe Chippaux – bitten by the snake bug
- Lhousseine Touqui, helping some thanks to others
- Lida Katsimpardi – on the hunt for an elixir of youth
- Lluis Quintana-Murci: discovering the world and humankind
- Mélodie Duval : les bactéries ont de l’avenir
- Nicolas Michalski, an engineer tackling auditory neuroscience
- Thomas Gregor - Following a passion through countries and disciplines
- Tracking down biomarkers with Eliette Touati
- Reportages
- Videos
- Press documents
- 13th edition of Pasteurdon: combating infectious diseases and cancer
- A blood factor involved in weight loss and aging
- COVID-19: mathematical model indicates that between 3% and 7% of French people have been infected
- International inaugural congress of the Hearing Institute
- Leishmania : a parasite that adapts to its environment by chromosomal amplification
- Revealing how SARS-CoV-2 hijacks human cells; points to drugs with potential to fight COVID-19 and a drug that aids its infectious growth
- The migration history of Bantu-speaking people: genomics reveals the benefits of admixture and sheds new light on slave trade
- Press area
- Press documents
- A new approach for improving BCG
- A new bacteria-killing weapon in the fight against antibiotic resistance
- A new breakthrough in developing effective antimalarial drugs
- A novel antibiotic resistance mechanism
- A preclinical study shows that hydroxychloroquine has no antiviral effect on SARS-CoV-2 in vivo
- A protective extracellular matrix underpins HIV infectivity
- AIDS research at the Institut Pasteur
- AIDS – an approach for targeting HIV reservoirs
- Achilles’ heel for reseeding of the viral reservoir after stem cell transplantation in people with HIV
- Allergies: cross-reactivity between cypress pollen and peaches/citrus fruits finally explained
- Allogeneic hematopoietic stem cells: work highlights the major changes in the human metabolome * in the graft against the host
- Anaphylactic shock: IgG antibodies and neutrophils play an unexpected role
- Anne Dejean-Assémat receives the Sjöberg Prize 2018
- Announcement of the 2018 ALBERT EINSTEIN World Award of Science
- Antibiotic resistance: a surprising timeline
- Benefits of early antiretroviral therapy in HIV-infected children
- Bill & Melinda Gates Medical Research Institute and the Institut Pasteur to Develop a Novel Vaccine Against Shigella
- Bruno Hoen appointed as Medical Research Director for the Institut Pasteur
- CEPI collaborates with the Institut Pasteur in a consortium to develop Covid-19 vaccine
- COVID-19 in primary schools: no significant transmission among children or from students to teachers
- COVID-19 – an intranasal lentiviral vaccine in development provides significant protection in animals
- COVID-19: no cross-protective immunity conferred by other coronaviruses in children
- COVID-19: the vast majority of patients with a minor form develop neutralizing antibodies
- Cancer under pressure: visualizing the activity of the immune system on tumor development
- Cervical cancer: New test enhances ability to predict risk
- Cholera outbreak in Yemen elucidated using genomics
- Cholera: understanding the link between the world’s major outbreaks paves the way to a better control strategy
- Christophe d’Enfert appointed as Scientific Director of the Institut Pasteur
- Chronic malnutrition in children: a new gut microbial signature
- Computerised biology, or how to control a population of cells with a computer
- Covid-19: 20 research projects selected to fight the epidemic
- Creation of the Alliance Pasteur Mérieux International
- Cryptococcal meningitis: validation of new therapeutic regimens
- Dengue: investigating antibodies to identify at-risk individuals
- Dengue: understanding the mechanisms that prevent the development of symptoms following infection
- Development and evaluation of four serological assays to detect SARS-CoV-2 antibodies and two assays to detect neutralizing antibodies
- Discovery of a crucial immune reaction when solid food is introduced that prevents inflammatory disorders
- Discovery of a new ribosomopathy in humans that results in a lack of testis-determination or testicular regression
- Dysentery: Shigella, bacteria with adaptation to respiration
- Editorial: Facing challenges with the novel coronavirus SARS-CoV-2 outbreak
- Editorial: How can we reach a level of herd immunity that will protect us from COVID-19 ?
- Emerging diseases: a highly mutant strain of the Elizabethkingia bacterium caused an outbreak in Wisconsin
- Estimating the effect of genetic mutations on neurodevelopmental disorders more accurately
- First Subject Enrolled in Phase I Clinical Trial of its non-opioid analgesic STR-324
- Five Institut Pasteur scientists receive 2017 L'Oréal-UNESCO "For Women in Science" Fellowships
- François Romaneix appointed Senior Executive Vice-President Administration and Finance of the Institut Pasteur
- GENETIC CONTROL OF HUMAN THYMIC FUNCTION : A NEEDLE IN AN HAYSTACK
- Gastric cancer susceptibility marker discovered
- Gastric cancer: a new strategy used by Helicobacter pylori to target mitochondria
- Gene therapy durably reverses congenital deafness in mice
- Gene therapy: first results in children with Sanfilippo B syndrome
- Genes play a role in empathy
- Genetics makes Asians and Europeans susceptible to severe dengue
- Gut microbiota imbalance promotes the onset of colorectal cancer
- Gut microbiota of mosquito larvae has an impact on adult insect’s ability to transmit human pathogens
- HIV: reprogramming cells to control infection
- HKU to Collaborate on Biomedical Innovation with the Institut Pasteur and Hong Kong Science and Technology Parks Corporation
- Hepatitis C: a novel point-of-care assay
- Hereditary hearing loss: the ear and auditory brain are both affected
- High-risk pregnancy: the interferon effect
- How Zika virus induces congenital microcephaly
- How bacteria invade us – Pascale Cossart honoured with 2018 Heinrich Wieland Prize
- How nicotine acts on the brains of schizophrenic patients
- In-Cell-Art, the Institut Pasteur and BioNet-Asia announce the collaborative development of a dengue vaccine candidate
- Infravec2 project launch: A European Commission 10M€ effort to fight mosquito-transmitted diseases
- Institut Pasteur isolates strains of coronavirus 2019-nCoV detected in France
- Institut Pasteur sequences the whole genome of the coronavirus, 2019-nCoV
- Link between a virus and sexual reproduction on Earth
- MV-SARS-CoV-2 vaccine candidate: a new partnership between Institut Pasteur, CEPI, Thémis and MSD
- Malaria: a genetic marker helps identify super-spreading mosquitoes
- Malaria: parasite resistance to artemisinin derivatives now affecting Africa
- Meningococcal meningitis: stomach pain should be seen as a warning sign
- Message from the Chairman of the Institut Pasteur Board of Directors
- New light shed on spread of resistance to carbapenems in Escherichia coli
- New neurons in the adult brain are involved in sensory learning
- New research suggests earlier emergence of malaria in Africa
- Nipah outbreaks in Bangladesh: age and breathing difficulties of infected patients increase the risk of disease spread
- Olivier Schwartz appointed as Scientific Director of the Institut Pasteur
- Phage therapy: synergy between bacteriophages and the immune system is essential
- Pierre-Marie Girard appointed as the Institut Pasteur's Vice-President International Affairs
- Professor Christine Petit receives the 2018 Kavli Prize
- Professor Stewart Cole appointed President of the Institut Pasteur
- Rift Valley fever virus: an infection mechanism identified
- Right/left: the heart of the matter
- Sanofi and the Institut Pasteur reward five researchers for their major contributions in the service of human health
- Smoking cessation: a genetic mutation involved in relapse
- The African Society of Venimology, French National Research Institute for Sustainable Development (IRD-France) and Institut Pasteur welcome WHO’s Decision to add Snakebites to Category A of the List of Neglected Tropical Diseases
- The behaviour of therapeutic antibodies in immunotherapy
- The new Institut Pasteur strategic plan for 2019-2023
- The overall annual cost of infections due to bacterial resistance in French hospitals now estimated up to 290 million Euros
- The sea anemone, an animal that hides its complexity well
- Titan Krios gives the Institut Pasteur a closer look at life
- Type 1 Interferon deficiency: A blood based Signature for Detecting Patients at risk of severe Covid-19 for a therapeutic approach
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- When Listeria monocytogenes goes to sleep….
- Why does bronchiolitis only affect infants?
- With its new "Omics" buildings, the Institut Pasteur continues its digital revolution
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- A SARS-CoV-2 genome sequencing technique to analyze low-quality clinical samples
- A combination of cutting-edge proteomic approaches for improving understanding of SARS-CoV-2 infection mechanisms
- A technique to identify key cellular factors for SARS-CoV-2 infection
- A zebrafish model to study SARS-CoV-2 neuroinvasion
- Accelerating the identification & design of SARS-CoV2 antiviral drugs in combination with the “DrugDesign_SARS2” project
- Air monitoring risk area
- Antibody profiling in recovering patients and development of a serological test for an epidemiological survey in individuals exposed to SARS-CoV-2
- Building a collection of human biological samples in France
- CEPI collaborates with the Institut Pasteur in a consortium to develop Covid-19 vaccine
- COVID-19 - The Bioinformatics and Biostatistics Hub on the front line
- COVID-19: mathematical model indicates that between 3% and 7% of French people have been infected
- Characterization of interaction between SARS-CoV-2 Nsp3 protein and non-canonical nucleic acid structures (G4) present in infected cells
- Characterization of variable systemic and mucosal immunity during SARS-CoV-2 infection and recovery
- Coronavirus (Covid-19) research projects
- Covid-19 risk evaluation among the household contacts of the first cases in Africa
- Deciphering the virus interactions with the entry receptors in human cells, and their potential inhibition
- Defective viral genomes (DVGs), potential antiviral inhibitors of SARS-CoV-2
- Descriptive study: epidemiological, clinical and immunological analysis of SARS-CoV-2 cases in the Metropolitan Region of São Paulo, Brazil
- Developing a rapid diagnostic test to detect SARS-CoV2 virus in various environment
- Development of an animal model and accelerated development of a DNA vaccine candidate
- Development of cell lines for research
- Development of novel nano-based multi-epitope vaccine against coronavirus SARS-CoV-2 - Generation of Humanized NSG transfer mouse model for vaccine testingAim: We hypothesize that it may be possible to generate protective anti-SARS-CoV-2 immuneresponse in
- Development of simple Covid-19 serological tools and targeted serosurvey of at-risk individuals
- Drug Repurposing & Design to inhibit the SARS-CoV2 proteases
- Engineering an ACE2 derived polypeptide for label-free, real-time detection on a smartphone device and therapeutic intervention
- Evaluating the determinants of coronavirus tropism in 3D models of human pulmonary epithelia
- Evaluation of SARS-CoV-2 infection spread in various populations groups in Cameroon
- Evaluation of clinical presentation and evolution of SARS -CoV-2 coronavirus infection in Senegal
- Evolution of SARS-CoV-2 and the antibody immune response in humans during infection
- Find potent antiviral drugs against SARS-CoV2 by targeting well identified proteins essential to the viral cycle
- Generation of animal models sensitive to SARS-CoV-2 to test vaccines or drugs
- Household transmission investigation study for SARS in overseas territories
- Identification and isolation of potent human neutralizing antibodies against SARS-CoV-2
- Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection
- Investigating the role of apico-basal proteins during SARS-Cov2 infection
- Investigation of the first cases of coronavirus (COVID-19) infections and their contacts in Antananarivo, Madagascar
- Isolating and characterizing the human antibodies that neutralize SARS-CoV-2
- LuLISA project, bioluminescence as a tool for human diagnostics, from allergy to Covid19
- Mechanisms of intercellular spreading of SARS-CoV-2: assessing the role of TNTs to escape immune surveillance and expand tropism and pathogenicity
- Modeling human SARS-CoV-2 infection in mice with human lung xenografts
- Monitoring the origins and transmission/spread of SARS-CoV-2 in Laos and Vietnam: searching for SARS-like viruses and detecting antibodies in vertebrates
- Neurological implications of SARS-COV-2 infection – a transversal study
- Neurological implications of SARS-COV-2 infection – a transversal study
- Nicotinic modulation of SARS-CoV-2 infection in the brain
- Origins, natural reservoirs and interspecies transmission of SARS-CoV-2 and other SARS-like coronaviruses
- Production of recombinant antigens from two SARS-CoV-2 proteins and generation of nano-antibodies against these proteins for diagnostic and therapeutic applications
- Profiling SARS-CoV-2 intra-viral and virus-host interactions on the basis of innate immunity signaling
- Protocol for assessment of potential risk factors for 2019-novel coronavirus (2019-nCoV) infection among health care workers in a health care setting
- Randomized trial of Covid-19 chemoprophylaxis in healthcare professionals
- Red Cross health workers and volunteers and continuity of care with COVID-19: an operational approach using mixed methods
- Restriction of SARS-CoV-2 replication by coding and non-coding genes
- SARS-CoV-2 fusion, replication and host responses
- Sequence the complete genome of Covid-19 directly and at low cost from prepared RNA samples from patients
- Serological surveillance of SARS-CoV-2 and seasonal coronaviruses
- Short Amplicon Based Sequencing Of SARS-CoV-2 for low-input samples
- Spike glycoprotein, lentiviral vectors and B/T-cell vaccine
- The use of Artificial Intelligence Methods to Discriminate Covid-19 from other Community Acquired Pneumopathy using Chest X-Ray and CT images
- Urgent Discovery of Drug Candidates That Target Coronavirus SARS-CoV-2
- Working towards controlled detection of SARS-CoV-2 by the innate immune system
- rBCG vaccine secreting SARS-CoV-2 antigens
- Covid-19 disease (novel coronavirus)
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- Dr. Didier Koumavi Ekouevi Wins the 2018 Dedonder-Clayton Award
- Dr. Richard Njouom laureate of the Dedonder-Clayton Prize 2017
- Elisabeth Carniel appointed Director General of the Pasteur Center in Cameroon
- Elliot Rakotomanana, an anthropologist against malnutrition in Madagascar
- Five young researchers from the Institut Pasteur International Network attended the 2017 PhD students' ceremony
- Five young researchers from the Institut Pasteur International Network, at the 2018 doctoral ceremony
- Food contamination in Cambodia contributing to the burden of antibiotic resistance
- Four young researchers from the Institut Pasteur International Network present at the 2019 PhD Student Ceremony
- Halima Maïnassara: from field investigator to director of CERMES in Niger
- Hepatitis B: to better identify patients eligible for treatment in Africa
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- In remembrance of Dr François Rouet
- In remembrance of Dr Vu Thi Que Huong
- Institut Pasteur and Hamad Bin Khalifa University will collaborate on training in the areas of genome research , precision medecine and disease prevention
- Institut Pasteur de Dakar: The 4-years research group Biostatistics, Bioinformatics and Modeling integrates the H3ABioNet pan-African network for bioinformatics
- International workshop in Iran to strengthen surveillance and control of rabies
- Malaria: Plasmodium falciparum protein MSP4 is a potential target for a vaccine
- Mamadou Aliou Barry, a lookout against epidemics in Senegal
- MediLabSecure: 4 years of health security improvement against vector-borne diseases in the Mediterranenan and Black Sea Regions
- Medical entomology for surveilling vector-borne diseases explained in motion design
- Meriem Ben Ali : a better diagnosis for immune deficiencies in Tunisia
- Moritoshi Iwagami Wins the 2018 Robert Deschiens Prize
- Multicentric research has identify Leptospira bacteria circulating in Uruguay
- National Health Laboratory Project launched
- New Pasteur-USP Scientific Platform in Brazil to tackle neurological disorders with a one health approach
- Pasteur International Network Association supported 3 statements at World Health Assembly 2018
- Pertussis : progress but lack of surveillance
- Rabies: a shorter, cheaper vaccination schedule following a suspected rabid dog bite
- Renewal of the status of the Pasteur International Network Association as a "non-State actor in official relationship" with WHO
- Report on the 49th Institut Pasteur International Network Directors' Council in Abidjan
- Researchers at the Institut Pasteur in French Guiana describe the persistence of Zika virus in semen
- Researchers from the Institut Pasteur in Iran and French Guiana Win the 2018 "Pasteur Talent" Award
- Roka village in Cambodia: a history of iatrogenic HIV infection
- Roman Thibeaux’s joust with bacterial armor
- Six institutions members of the Institut Pasteur international network engaged in an international coalition against epidemics in Africa
- Spencer Shorte appointed Chief Scientific Officer to Institut Pasteur Korea
- Strong increase in antibiotic resistance in Cambodia
- Successful second international medical entomology course in Vientiane, Laos
- The 2019 "Prince Albert II of Monaco - Institut Pasteur" Prize is awarded to Joacim Rocklöv
- The 49th Institut Pasteur International Network Directors council will be held in Abidjan
- The Chinese Ambassador to France visits the Institut Pasteur
- The FioCruz-Pasteur-USP tripartite agreement is bearing fruits
- The Institut Pasteur International Network enters the GloPID-R alliance
- The Institut Pasteur International Network pays tribute to Professor Ogobara Doumbo
- The Institut Pasteur de Guinée opens its first laboratory in Conakry
- The Institut Pasteur de Nouvelle-Calédonie describes 12 new species of leptospires and pays tribute to Pasteurians
- The Institut Pasteur in French Guiana confirms a case of yellow fever
- The Institut Pasteur launches a Scientific Platform in the university of São Paulo Research and Innovation Center
- The first "Pasteur International Talent" reward two young scientists of the Institut Pasteur in Guadeloupe and Montevideo
- The medical entomology course at the Institut Pasteur celebrates its 30th anniversary
- Three projects from the Institut Pasteur in Dakar and Madagascar selected for funding by AESA’s Grand Challenge Africa
- Twelve new species of Leptospira discovered in New Caledonian soils
- Vaccines: a life insurance for humankind
- Viral hepatitis: the challenge of communication in Africa
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- From Molecular Biology to Stem Cells
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- Salmonella outbreak: Institut Pasteur raises the alarm
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- The Institut Pasteur in 2018: A legacy of excellence
- The Research Journal : the most read articles in 2017!
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- "N-terminomics" reveals how Listeria bacteria detect and react to stress
- "Pasteur, the experimenter" – the must-see exhibition!
- "Pasteur, the microbe legacy" lecture cycle
- 130 years ago, the Institut Pasteur opened its doors for the first time
- 130 years ago, the Institut Pasteur was under construction
- 2016 yellow fever outbreak in Brazil: tiger mosquitoes are also capable of transmitting the virus
- 2018 Activity Report for the Pasteur Microbes and Health Carnot Institute
- A Task Force for responding to outbreaks such as Zika
- A biological interface for prostheses: the futuristic project of the 2018 Pasteur iGEM team
- A breakthrough in understanding the innate immune response activated by dengue and Zika viruses
- A comprehensive analysis of midbodies, bridges between dividing cells
- A debate on sepsis at the Institut Pasteur
- A fast likelihood method to reconstruct and visualize ancestral scenarios
- A high level international conference on microbes and vectors resistance
- A link between the microbiota and the severity of tuberculosis
- A microbial virus from extreme environments opens doors to new therapeutical strategies
- A modular gene enhancer plays a role in leukemia
- A new 800 MHz nuclear magnetic resonance instrument at the Institut Pasteur
- A new Listeria species from Costa Rica identified
- A new approach for deciphering complex immune responses
- A new biochemical pathway implicated in the proliferation of cancer cells
- A new biotechnology tool to tackle antibiotic resistance
- A new breakthrough in limb development
- A new call for students by the PPU International doctoral program
- A new mathematical approach to measure the reliability of phylogenetic trees in the big data era
- A new mechanism used by group B Streptococcus to evade the host immune system
- A new signaling pathway in the proliferation of cardiac cells
- A new step in understanding the mechanisms that control cilia length
- A research ethics committee at the Institut Pasteur since 2009
- A strategy for attenuating a virus by modifying its evolutionary potential
- A theory to link genes with social awareness
- A tobacco-dependence gene responsible for alcohol dependence
- AIDS: NK cells in the innate immune system control viral replication in the lymph nodes
- Adapt to survive: the intestinal microbiota promotes viral persistence
- Aimee Wessel and Raphaël Tomasi win the i-Lab award for their MultiScreen project
- Airborne Bacterial Volatiles stimulate Fungal Growth
- Alexandre Yersin, the man who discovered the bacterium responsible for the plague
- An innovative tool to study psychiatric or infectious diseases
- An international conference on Emerging Infections & Pandemic Risk
- An update on Ebola in the Democratic Republic of the Congo with Arnaud Fontanet, an expert at the Institut Pasteur
- An update on the Institut Pasteur's work on CRISPR-CAS9
- Artificial intelligence speeds up high-resolution microscopy
- Artificial intelligence: a new platform for the biomedical community
- Artificial intelligence: deep learning is blazing ahead
- At the Institut Pasteur, a new insectarium for arbovirus mosquito vectors
- Autism: a virtual avatar to make precision medicine
- Award for the DIVA platform at the Start-Ulm competition
- Bacterial Achilles' heel discovered providing a new target for antimicrobial treatments
- Biotechnology: DNA polymerases that can replicate DNA without a primer!
- Blood test: a potential new tool for controlling infections
- Book release: “Institut Pasteur: Today's Research, Tomorrow's Medicine”
- COVID-19 - The Bioinformatics and Biostatistics Hub on the front line
- COVID-19, chronicle of an expected pandemic / Exiting lockdown or the sum total of all dangers
- COVID-19: the latest on the epidemic situation and why caution is still needed
- Catherine Rougeot and the discovery of a new painkiller molecule
- Cellular therapy: identification of circulating human Innate Lymphoid Cell Precursors
- Ceremony for the 2019 Pasteur Vallery-Radot Prize (awarded by the BnF)
- Chaos in ageing skeletal muscle stem cells
- Chikungunya spreads in and around homes with women at highest risk
- Chikungunya: the specific interactions between the genotypes of mosquitoes and viruses have influenced Ae. albopictus vector competence for the virus
- Christine Petit and her discoveries concerning early-onset hearing loss
- Christine Petit receives the ARO Award of Merit for her work to elucidate the mechanisms of hearing and deafness
- Contact with monkeys and apes puts populations at risk
- Covid-19: a study in children with hyper-inflammatory syndrome related to Kawasaki disease
- Culex mosquitoes do not transmit Zika virus
- DIVA: Virtual reality for complex image analysis
- DNA viruses infiltrate 3D cellular genome organization and preferentially contact active chromatin
- Daniel Iffla-Osiris, a great 19th-century philanthropist and the Institut Pasteur's most generous donor
- Decades-long trends, rather than flawed vaccine, best explain resurgent whooping cough
- Deep-learning to improve super-resolution microscopy methods
- Demystifying immunity in the bladder
- Depression: the key role of neuroinflammation
- Destroying Helicobacter pylori by disrupting synthesis of its cell wall!
- Discovery of a mechanism responsible for chronic inflammation in patients suffering from multiple sclerosis
- Discovery of a restriction factor for hepatitis B virus
- Discovery of new strains of the HTLV-4 virus in hunters bitten by gorillas in Gabon
- Discovery of the mechanism used to coordinate replication of the two Vibrio cholerae chromosomes
- Distinguishing resistence from resilience to prolong antibiotic potency
- Division – a key moment in establishing cell polarity
- Drastic reduction of exposure to malaria in Senegal
- EDF Group Foundation supports the Institut Pasteur and the DIVA project
- ERC grants: scientific excellence supported by Europe
- Ebola: the answers to your questions in our disease sheet
- Economist Jim O’Neill, and other experts, discuss Antimicrobial Resistance at the Institut Pasteur
- Effect of the seasons on pneumococcal infections
- Efficacy of cancer treatment: two bacteria in the microbiota identified
- Esrrb transcription factor plays a key role in maintaining stem cell identity even after countless divisions
- Establishment of the Hearing Institute, a new Institut Pasteur center: scientific experts within the field of hearing brought together for a high-level international meeting
- Exhibition in honor of Jules Bordet at the Université libre de Bruxelles
- Exhibition: the amazing achievements of "Pasteur, the experimenter"!
- Existing drugs can prevent SARS-CoV-2 from hijacking cells
- Explanation and advice following the case of rabies in France
- First statement from the Pasteur International Network association to the World Health Assembly
- First stone laid for the Institut Pasteur in Guinea
- Following maternal transmission, group B strep mutates to sicken infants
- Fondation IPSEN supports new MOOCs at the Institut Pasteur
- Foreign travel – a tonic for the health?
- Françoise Barré-Sinoussi and her research on the HIV-1 virus
- Françoise Barré-Sinoussi elected as a member of the US National Academy of Medicine
- Frédéric Tangy, expert from the Institut Pasteur, talks about vaccines of today and tomorrow
- Genetic cause of difference in sexual development uncovered
- Genomics study in Africa: demographic history and deleterious mutations
- Gut microbiota: surprising interactions between pathogenic and commensal bacteria
- HIV-1: revealed during the nuclear entry step. Direct visualization in living cells using “HIV-1 ANCHOR” technology
- Health and environment: Institut Pasteur and AFD commit to a new program
- Hepatitis B may infect twice more African babies than HIV
- Hepatitis B: natural controllers shed light on immunity mechanisms
- High-level microscopy unveils bacteria’s adaptation mechanisms
- How Chlamydia trachomatis hijacks energy stores from its host
- How Helicobacter pylori survives gastric acidity
- How Listeria monocytogenes blocks intestinal villus invasion
- How does Legionella pneumophila, the bacterium causing legionellosis, use the host cell machinery to its own advantage?
- How dying cells regulate immunity
- How human pathogens may emerge from the environment
- How investigating the population biology of Listeria is ushering in a new era in listeriosis surveillance
- How the influenza virus achieves efficient viral RNA replication
- Human contact plays big role in spread of some hospital infections, but not others
- Icypro, an advanced bioimage analysis platform for health technology professionals
- Identification of a new bacterial defense system against phages
- IgG antibodies activate blood platelets and contribute to the severity of anaphylaxis
- Immature heart cells persist in the adult heart and react to infarction
- Immune cells fighting blood cancer visualized for the first time
- In France, Aedes albopictus better transmits the African "Zika" than the Asian one
- In the Pasteur library with Hervé Di Rosa
- Inauguration of the Hearing Institute, an Institut Pasteur center
- Infant nutrition: an overly rich diet may increase susceptibility to inflammatory diseases
- Infravec2 new insect vector research tools: no-cost resources for scientists fighting mosquito-transmitted diseases
- Innate immune responses – redefining how innate lymphoid cells develop
- Insect vectors: a mosquito capable of limiting viral infection
- Insecticide resistance genes affect vector competence for West Nile virus
- Institut Pasteur in Guinea: One Health training to strengthen local expertise
- Institut Pasteur scientists during the Great War
- Institut Pasteur team identifies a key protein linked to ageing
- International Women's Day 2019
- Interview with Prof. Jean-François Delfraissy about French National Bioethics Consultation, a forum for the public and the research community
- Just the two of us: Holding hands can ease pain, sync brainwaves
- Key cellular factors for chikungunya virus replication identified
- Lassa fever: vaccine set to be trialed
- Launch of the recruitment process for the Director of the Institut Pasteur
- Leishmaniasis: epigenetic mechanisms implicated in infection
- Listeriosis: food type determines Listeria monocytogenes virulence
- Liver cancer: the Peruvian exception
- Long-awaited determination of the 3D structure of a human transporter
- Low competence of Aedes mosquitoes for Zika virus transmission
- LuLISA project, bioluminescence as a tool for human diagnostics, from allergy to Covid19
- Lyme disease – chipmunks may affect tick infection but the risk of transmission is more complex
- Lyme disease: a study on the speed of transmission by infected ticks
- Mechanism of activation of a major toxin involved in whooping cough
- Meningitis: analysis of the long-term protection of the MenAfriVac vaccine
- Meningococcal infection: bacterial aggregates form a thick honey-like liquid that flows through blood vessels
- Microbiota and solid food introduction: interview with Gérard Eberl
- Modeling to monitor and anticipate the Zika outbreak in Martinique
- Monkeypox: the epidemic potential will continue increasing, with diminishing herd immunity against viruses responsible for smallpox
- MosKeyTool: a free and interactive tool to identify mosquitoes of the Euro-Mediterranean region
- Mosquitoes and viruses by Sarah Merkling
- Multiscale structure of the Escherichia coli genome
- Natural molecules to stimulate human antimicrobial defenses
- Neurobiologist Jean-Pierre Changeux tells us the story of the nicotinic acetylcholine receptor
- Neurodegenerative diseases: recycling mechanisms open up new avenues for therapy
- Neurodevelopmental disorders: a daily practical guide by InovAND to help families deal with the difficulties of lockdown
- Neurological impact of the Zika virus finally exposed
- New Fellowships have been announced to enhance the next generation of global health leaders
- New insight into body's response to killer fungus
- Novel coronavirus (SARS-CoV-2): what we know about the disease
- Novel neurotropic arbovirus identified in France: the Umbre virus
- Olivier Gascuel: Inria – French Académie des sciences Grand Prize
- Omics: Biology in the digital age at the Institut Pasteur
- Parkinson's: new discoveries about nanotubes, transporters of toxic proteins
- Pasteur iGEM 2019: simplified diagnosis of bacterial infections
- Pasteur's Nephew – Or the Adventurous Life of Adrien Loir, Scholar and Globe-Trotter
- Pasteurdon 2019: Graffitti artists meet scientists and create stunning lab coats
- Phage therapy effective in Crohn's disease
- Phagotherapy: a support for the work on bacteriophages of a Franco-American team (Institut Pasteur and Georgia Tech)
- Phylogenetic analysis of SARS-CoV-2: strengths, limitations and over-interpretations
- Plague outbreak: advice for travelers to Madagascar
- Progress in the understanding of the mechanisms of genetic diversification in a major fungal pathogen of humans, Candida albicans
- Proof-of-concept study reveals feasibility of eliminating rabies in Africa
- Quiescent cells also mutate!
- Rabies in Cambodia
- Rabies: new prophylactic and therapeutic avenues
- Regulation of metabolic pathways: lessons from an intracellular bacterium
- Regulation of muscle stem cells in their niche: juggling external and internal cues
- Report on the 2018 Pasteur Vallery-Radot Prize
- Réseau Bactériophages France receives the François Sommer Foundation scientific prize
- S3ODEON 2019 – Institut Pasteur partner to an event linking science and society
- SODA, a new analysis tool for fluorescence imaging
- Severe inflammation: clues towards a therapeutic approach using immune memory
- Sex-based differences influence chronicity in urinary tract infections
- Shedding light on almost indestructible archaeal pili
- Shedding light on the burden of dengue in Bangladesh
- Sign up for the upcoming Institut Pasteur MOOCs
- Sleeping sickness: one step further in improving diagnosis
- Small intestine regulates immune surveillance of colorectal cancer during chemotherapy treatment
- Staphylococcus aureus: a new mechanism involved in virulence and antibiotic resistance
- Study reveals conditions for the onset of severe forms of COVID-19
- Studying synaptic protein assemblies helps us understand the nature of communication between neurons
- Success of the 2019 Z Event in aid of the Institut Pasteur
- Summer University dedicated to the creation of life sciences company
- Support for government policy for the prevention of infectious diseases
- Table salt to diagnose malaria
- Ten years ago, Françoise Barré-Sinoussi and Luc Montagnier won the Nobel Prize in Medicine
- Thank you, Simone Veil!
- The 2016 Pasteur Vallery-Radot Prize
- The 2017 Pasteur iGEM team – a purifying and recycling device
- The 2018 Institut Pasteur Annual Report is available
- The BTP PLUS Foundation is funding a research project to fight asbestos cancer
- The Ebola virus adapted to better infect humans during the 2013-2016 epidemic
- The French Parliamentary Office of Science and Technology pays a visit to the Institut Pasteur
- The ISG15 protein plays a key role in fighting bacterial infections
- The Institut Pasteur in Côte d'Ivoire diagnoses a dengue epidemic in Abidjan
- The Institut Pasteur wishes you a happy new year 2020
- The Institut Pasteur: a leader in the fight against antibiotic resistance
- The Musée Pasteur featured in book of Parisian hidden gems
- The Zika virus modifies the morphology of the cells and makes them implode
- The book “Institut Pasteur: Today's Research, Tomorrow's Medicine” available in US bookstores
- The documentary Unseen Enemy in streaming on ARTE.TV
- The factors that most affect our immune system
- The first "3D" metagenomics experiment on a complex natural microbiome
- The first case of prolonged remission in an HIV-infected child – an interview with Asier Saez-Cirion
- The hidden population of multidrug-resistant Klebsiella bacteria colonizing the human digestive tract
- The issues of epidemiology with Arnaud Fontanet
- The long history of medical entomology
- The molecular crossbow: a vital weapon in the bacterial arsenal
- The shape of the heart as explained by Audrey Desgrange
- The structure and assembly of the Enterohemorrhagic Escherichia coli type 4 pilus deciphered
- The tiger mosquito returns to France: 51 départements on red alert
- The web meets genomics: a DNA search engine for microbes
- Third type of membrane envelope in a hyperthermophilic virus
- This week, France Culture's flagship documentary series explores the life and work of Louis Pasteur
- Tiger mosquito in France: 58 départements on red alert
- Tiger mosquitoes: heightened surveillance in France, from May to November 2018
- Titan Krios (TM): inauguration of the world’s most powerful microscope at the Institut Pasteur
- Tribute to the Institut Pasteur in Genes & Immunity
- Tumor cells eliminating their neighbors using a newly discovered mechanism
- Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes
- Two major types of rabies that evolved in different ways
- Unmasking an ancestral mechanism of integrons — key players in antibiotic resistance
- Unseen Enemy, a film about our vulnerability to global epidemics
- Usher syndrome type III: cochlear gene therapy preserves hair cell synaptic transmission to the auditory neurons
- Using medicinal chemistry to improve diagnostic methods
- Viral sequence integrated in mosquito genome controls infection by related virus
- What is the "tiger mosquito" (Aedes albopictus)?
- When Listeria attacks the intestinal microbiota
- When the structure of Tunneling nanotubes (TNTs) challenges the very concept of cell
- Whooping cough: elucidation of a critical stage in the action of the CyaA toxin
- Why some patients develop resistance to new class of anti-cancer drugs
- Why vaccines are essential
- Yellow fever: using modeling to optimize the use of vaccine stocks
- Yersinia – a novel genomic tool for identifying strains
- Zika: two indigenous cases for the first time in mainland France
- i-Lab 2020 competition: two winners from the Institut Pasteur, one awarded a Grand Prix
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- 3D research according to Albane Imbert, an engineer at the Institut Pasteur
- An Epidemiologist Faces Ebola in The Democratic Republic of the Congo
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- Diego Cordero Cervantes, globe-trotting researcher
- Fabrice Chrétien, from stethoscope to microscope
- Fani Koukouli: A young researcher's odyssey to the inner depths of the brain
- For Asier Sáez-Cirión, research is an incurable passion
- Humans, animals and their environment, an investigation by Victor Narat
- Jean-Philippe Chippaux – bitten by the snake bug
- Lhousseine Touqui, helping some thanks to others
- Lida Katsimpardi – on the hunt for an elixir of youth
- Lluis Quintana-Murci: discovering the world and humankind
- Mélodie Duval : les bactéries ont de l’avenir
- Nicolas Michalski, an engineer tackling auditory neuroscience
- Thomas Gregor - Following a passion through countries and disciplines
- Tracking down biomarkers with Eliette Touati
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- 13th edition of Pasteurdon: combating infectious diseases and cancer
- A blood factor involved in weight loss and aging
- COVID-19: mathematical model indicates that between 3% and 7% of French people have been infected
- International inaugural congress of the Hearing Institute
- Leishmania : a parasite that adapts to its environment by chromosomal amplification
- Revealing how SARS-CoV-2 hijacks human cells; points to drugs with potential to fight COVID-19 and a drug that aids its infectious growth
- The migration history of Bantu-speaking people: genomics reveals the benefits of admixture and sheds new light on slave trade
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- A new approach for improving BCG
- A new bacteria-killing weapon in the fight against antibiotic resistance
- A new breakthrough in developing effective antimalarial drugs
- A novel antibiotic resistance mechanism
- A preclinical study shows that hydroxychloroquine has no antiviral effect on SARS-CoV-2 in vivo
- A protective extracellular matrix underpins HIV infectivity
- AIDS research at the Institut Pasteur
- AIDS – an approach for targeting HIV reservoirs
- Achilles’ heel for reseeding of the viral reservoir after stem cell transplantation in people with HIV
- Allergies: cross-reactivity between cypress pollen and peaches/citrus fruits finally explained
- Allogeneic hematopoietic stem cells: work highlights the major changes in the human metabolome * in the graft against the host
- Anaphylactic shock: IgG antibodies and neutrophils play an unexpected role
- Anne Dejean-Assémat receives the Sjöberg Prize 2018
- Announcement of the 2018 ALBERT EINSTEIN World Award of Science
- Antibiotic resistance: a surprising timeline
- Benefits of early antiretroviral therapy in HIV-infected children
- Bill & Melinda Gates Medical Research Institute and the Institut Pasteur to Develop a Novel Vaccine Against Shigella
- Bruno Hoen appointed as Medical Research Director for the Institut Pasteur
- CEPI collaborates with the Institut Pasteur in a consortium to develop Covid-19 vaccine
- COVID-19 in primary schools: no significant transmission among children or from students to teachers
- COVID-19 – an intranasal lentiviral vaccine in development provides significant protection in animals
- COVID-19: no cross-protective immunity conferred by other coronaviruses in children
- COVID-19: the vast majority of patients with a minor form develop neutralizing antibodies
- Cancer under pressure: visualizing the activity of the immune system on tumor development
- Cervical cancer: New test enhances ability to predict risk
- Cholera outbreak in Yemen elucidated using genomics
- Cholera: understanding the link between the world’s major outbreaks paves the way to a better control strategy
- Christophe d’Enfert appointed as Scientific Director of the Institut Pasteur
- Chronic malnutrition in children: a new gut microbial signature
- Computerised biology, or how to control a population of cells with a computer
- Covid-19: 20 research projects selected to fight the epidemic
- Creation of the Alliance Pasteur Mérieux International
- Cryptococcal meningitis: validation of new therapeutic regimens
- Dengue: investigating antibodies to identify at-risk individuals
- Dengue: understanding the mechanisms that prevent the development of symptoms following infection
- Development and evaluation of four serological assays to detect SARS-CoV-2 antibodies and two assays to detect neutralizing antibodies
- Discovery of a crucial immune reaction when solid food is introduced that prevents inflammatory disorders
- Discovery of a new ribosomopathy in humans that results in a lack of testis-determination or testicular regression
- Dysentery: Shigella, bacteria with adaptation to respiration
- Editorial: Facing challenges with the novel coronavirus SARS-CoV-2 outbreak
- Editorial: How can we reach a level of herd immunity that will protect us from COVID-19 ?
- Emerging diseases: a highly mutant strain of the Elizabethkingia bacterium caused an outbreak in Wisconsin
- Estimating the effect of genetic mutations on neurodevelopmental disorders more accurately
- First Subject Enrolled in Phase I Clinical Trial of its non-opioid analgesic STR-324
- Five Institut Pasteur scientists receive 2017 L'Oréal-UNESCO "For Women in Science" Fellowships
- François Romaneix appointed Senior Executive Vice-President Administration and Finance of the Institut Pasteur
- GENETIC CONTROL OF HUMAN THYMIC FUNCTION : A NEEDLE IN AN HAYSTACK
- Gastric cancer susceptibility marker discovered
- Gastric cancer: a new strategy used by Helicobacter pylori to target mitochondria
- Gene therapy durably reverses congenital deafness in mice
- Gene therapy: first results in children with Sanfilippo B syndrome
- Genes play a role in empathy
- Genetics makes Asians and Europeans susceptible to severe dengue
- Gut microbiota imbalance promotes the onset of colorectal cancer
- Gut microbiota of mosquito larvae has an impact on adult insect’s ability to transmit human pathogens
- HIV: reprogramming cells to control infection
- HKU to Collaborate on Biomedical Innovation with the Institut Pasteur and Hong Kong Science and Technology Parks Corporation
- Hepatitis C: a novel point-of-care assay
- Hereditary hearing loss: the ear and auditory brain are both affected
- High-risk pregnancy: the interferon effect
- How Zika virus induces congenital microcephaly
- How bacteria invade us – Pascale Cossart honoured with 2018 Heinrich Wieland Prize
- How nicotine acts on the brains of schizophrenic patients
- In-Cell-Art, the Institut Pasteur and BioNet-Asia announce the collaborative development of a dengue vaccine candidate
- Infravec2 project launch: A European Commission 10M€ effort to fight mosquito-transmitted diseases
- Institut Pasteur isolates strains of coronavirus 2019-nCoV detected in France
- Institut Pasteur sequences the whole genome of the coronavirus, 2019-nCoV
- Link between a virus and sexual reproduction on Earth
- MV-SARS-CoV-2 vaccine candidate: a new partnership between Institut Pasteur, CEPI, Thémis and MSD
- Malaria: a genetic marker helps identify super-spreading mosquitoes
- Malaria: parasite resistance to artemisinin derivatives now affecting Africa
- Meningococcal meningitis: stomach pain should be seen as a warning sign
- Message from the Chairman of the Institut Pasteur Board of Directors
- New light shed on spread of resistance to carbapenems in Escherichia coli
- New neurons in the adult brain are involved in sensory learning
- New research suggests earlier emergence of malaria in Africa
- Nipah outbreaks in Bangladesh: age and breathing difficulties of infected patients increase the risk of disease spread
- Olivier Schwartz appointed as Scientific Director of the Institut Pasteur
- Phage therapy: synergy between bacteriophages and the immune system is essential
- Pierre-Marie Girard appointed as the Institut Pasteur's Vice-President International Affairs
- Professor Christine Petit receives the 2018 Kavli Prize
- Professor Stewart Cole appointed President of the Institut Pasteur
- Rift Valley fever virus: an infection mechanism identified
- Right/left: the heart of the matter
- Sanofi and the Institut Pasteur reward five researchers for their major contributions in the service of human health
- Smoking cessation: a genetic mutation involved in relapse
- The African Society of Venimology, French National Research Institute for Sustainable Development (IRD-France) and Institut Pasteur welcome WHO’s Decision to add Snakebites to Category A of the List of Neglected Tropical Diseases
- The behaviour of therapeutic antibodies in immunotherapy
- The new Institut Pasteur strategic plan for 2019-2023
- The overall annual cost of infections due to bacterial resistance in French hospitals now estimated up to 290 million Euros
- The sea anemone, an animal that hides its complexity well
- Titan Krios gives the Institut Pasteur a closer look at life
- Type 1 Interferon deficiency: A blood based Signature for Detecting Patients at risk of severe Covid-19 for a therapeutic approach
- VIH : une piste de thérapie cellulaire issue de la recherche sur les patients « contrôleurs »
- When Listeria monocytogenes goes to sleep….
- Why does bronchiolitis only affect infants?
- With its new "Omics" buildings, the Institut Pasteur continues its digital revolution
- Yellow fever: a new method for testing vaccine safety
- Zika: an accurate estimation of the neurological risks in unborn children
- Zika: silent long-term circulation in Thailand
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- All SARS-CoV-2 / COVID-19 from the Institut Pasteur
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- Research Projects
- A SARS-CoV-2 genome sequencing technique to analyze low-quality clinical samples
- A combination of cutting-edge proteomic approaches for improving understanding of SARS-CoV-2 infection mechanisms
- A technique to identify key cellular factors for SARS-CoV-2 infection
- A zebrafish model to study SARS-CoV-2 neuroinvasion
- Accelerating the identification & design of SARS-CoV2 antiviral drugs in combination with the “DrugDesign_SARS2” project
- Air monitoring risk area
- Antibody profiling in recovering patients and development of a serological test for an epidemiological survey in individuals exposed to SARS-CoV-2
- Building a collection of human biological samples in France
- CEPI collaborates with the Institut Pasteur in a consortium to develop Covid-19 vaccine
- COVID-19 - The Bioinformatics and Biostatistics Hub on the front line
- COVID-19: mathematical model indicates that between 3% and 7% of French people have been infected
- Characterization of interaction between SARS-CoV-2 Nsp3 protein and non-canonical nucleic acid structures (G4) present in infected cells
- Characterization of variable systemic and mucosal immunity during SARS-CoV-2 infection and recovery
- Coronavirus (Covid-19) research projects
- Covid-19 risk evaluation among the household contacts of the first cases in Africa
- Deciphering the virus interactions with the entry receptors in human cells, and their potential inhibition
- Defective viral genomes (DVGs), potential antiviral inhibitors of SARS-CoV-2
- Descriptive study: epidemiological, clinical and immunological analysis of SARS-CoV-2 cases in the Metropolitan Region of São Paulo, Brazil
- Developing a rapid diagnostic test to detect SARS-CoV2 virus in various environment
- Development of an animal model and accelerated development of a DNA vaccine candidate
- Development of cell lines for research
- Development of novel nano-based multi-epitope vaccine against coronavirus SARS-CoV-2 - Generation of Humanized NSG transfer mouse model for vaccine testingAim: We hypothesize that it may be possible to generate protective anti-SARS-CoV-2 immuneresponse in
- Development of simple Covid-19 serological tools and targeted serosurvey of at-risk individuals
- Drug Repurposing & Design to inhibit the SARS-CoV2 proteases
- Engineering an ACE2 derived polypeptide for label-free, real-time detection on a smartphone device and therapeutic intervention
- Evaluating the determinants of coronavirus tropism in 3D models of human pulmonary epithelia
- Evaluation of SARS-CoV-2 infection spread in various populations groups in Cameroon
- Evaluation of clinical presentation and evolution of SARS -CoV-2 coronavirus infection in Senegal
- Evolution of SARS-CoV-2 and the antibody immune response in humans during infection
- Find potent antiviral drugs against SARS-CoV2 by targeting well identified proteins essential to the viral cycle
- Generation of animal models sensitive to SARS-CoV-2 to test vaccines or drugs
- Household transmission investigation study for SARS in overseas territories
- Identification and isolation of potent human neutralizing antibodies against SARS-CoV-2
- Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection
- Investigating the role of apico-basal proteins during SARS-Cov2 infection
- Investigation of the first cases of coronavirus (COVID-19) infections and their contacts in Antananarivo, Madagascar
- Isolating and characterizing the human antibodies that neutralize SARS-CoV-2
- LuLISA project, bioluminescence as a tool for human diagnostics, from allergy to Covid19
- Mechanisms of intercellular spreading of SARS-CoV-2: assessing the role of TNTs to escape immune surveillance and expand tropism and pathogenicity
- Modeling human SARS-CoV-2 infection in mice with human lung xenografts
- Monitoring the origins and transmission/spread of SARS-CoV-2 in Laos and Vietnam: searching for SARS-like viruses and detecting antibodies in vertebrates
- Neurological implications of SARS-COV-2 infection – a transversal study
- Neurological implications of SARS-COV-2 infection – a transversal study
- Nicotinic modulation of SARS-CoV-2 infection in the brain
- Origins, natural reservoirs and interspecies transmission of SARS-CoV-2 and other SARS-like coronaviruses
- Production of recombinant antigens from two SARS-CoV-2 proteins and generation of nano-antibodies against these proteins for diagnostic and therapeutic applications
- Profiling SARS-CoV-2 intra-viral and virus-host interactions on the basis of innate immunity signaling
- Protocol for assessment of potential risk factors for 2019-novel coronavirus (2019-nCoV) infection among health care workers in a health care setting
- Randomized trial of Covid-19 chemoprophylaxis in healthcare professionals
- Red Cross health workers and volunteers and continuity of care with COVID-19: an operational approach using mixed methods
- Restriction of SARS-CoV-2 replication by coding and non-coding genes
- SARS-CoV-2 fusion, replication and host responses
- Sequence the complete genome of Covid-19 directly and at low cost from prepared RNA samples from patients
- Serological surveillance of SARS-CoV-2 and seasonal coronaviruses
- Short Amplicon Based Sequencing Of SARS-CoV-2 for low-input samples
- Spike glycoprotein, lentiviral vectors and B/T-cell vaccine
- The use of Artificial Intelligence Methods to Discriminate Covid-19 from other Community Acquired Pneumopathy using Chest X-Ray and CT images
- Urgent Discovery of Drug Candidates That Target Coronavirus SARS-CoV-2
- Working towards controlled detection of SARS-CoV-2 by the innate immune system
- rBCG vaccine secreting SARS-CoV-2 antigens
- Covid-19 disease (novel coronavirus)
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yersinia
News
2019.10.15
The Yersinia genus covers a vast range of bacteria that are distinguished by criteria such as whether or not they are able to cause disease (their...
News
2019.05.13
On the occasion of the high-level meeting showcasing 130 years of Science at the Institut Pasteur, the Genes & Immunity Journal published a special issue...
News
2018.12.18
Entomology, the study of insects, is a long-standing tradition at the Institut Pasteur. Institut Pasteur scientist Alphonse Laveran was the first to describe...
News
2018.04.12
Listeria costaricensis is the official name given to the new bacterial species described by investigators from the Costa Rican Institute of Technology (TEC)...
Document de presse
2017.11.30
Scientists from the Institut Pasteur have retrospectively identified early cases of Salmonella resistance to ampicillin, a broad-spectrum antibiotic that is...
News
2017.11.22
An outbreak of pneumonic plague has been ongoing in Madagascar for several weeks. As indicated on the World Health Organization (WHO) website, "based on the...
News
2017.10.09
Swiss-born Alexandre Yersin joined the Institut Pasteur in 1885 aged just 22 and worked under Émile Roux. He discovered the plague bacillus in Hong Kong. A...
News
2017.02.02
On the African continent, diarrheal diseases are very frequent but their etiology is often unknown which does not allow an optimal care of the patients....