The Institut Pasteur, a Carnot institute since 2007, and ABL Diagnostics, a Euronext-listed leader in molecular diagnostics, recently signed a licensing agreement for the integration of the innovative HPV RNA sequencing technology into ABL Diagnostics solutions, which will produce and market the test.
HPV RNA-Seq is a cutting-edge diagnostic method that enhances the detection and typing of high-risk human papillomavirus (HPV) infections. This technology not only identifies the presence of HPV but also determines the specific viral strains and assesses the risk of progression to cervical cancer. HPV RNA-Seq demonstrated superior sensitivity compared to traditional DNA-based tests, detecting additional HPV-positive cases and multiple infections that were previously unrecognized (https://doi.org/10.1016/j.jmoldx.2019.04.010).
Furthermore, HPV RNA-Seq technology is already capable of competing with cytology tests, providing a highly sensitive and precise alternative for HPV monitoring. Its advanced capabilities make it a true game changer, as it has the potential to ultimately replace HPV screening tests altogether. By offering a more reliable method for early detection and risk assessment, this technology revolutionizes current strategies for monitoring HPV patients and significantly enhances patient care.
“We worked for several years to develop the HPV RNA seq technology at the Institut Pasteur, together with Prof. Marc Eloit, inventor of the technology. Support from the Institut Pasteur Innovation Accelerator and guidance from the Technology Transfer and Industrial Partnership Department (DARRI) were decisive in achieving a sufficient TRL and envisaging an industrial transfer. The signature of the license with ABL Diagnostics marks an important milestone in the project. We are convinced that this collaboration will enable us to put this innovation at the service of clinicians and patients, thus contributing to the prevention of cervical cancer”, added Philippe Pérot, co-inventor of the HPV RNA- Seq technology and Expert Research Engineer at the Institut Pasteur.
