Clinical Investigation and Access to BioResources (ICAReB)



The ICAReB platform was set up in 2008 on the Institut Pasteur (IP) campus, to give access to high-quality bio-human resources for the research units. This is part of the IP themes of interest: infectious diseases, immunology and, in recent years, neuroscience. The platform has developed two activities in parallel, hence its name ("ICAReB" for Clinical Investigation and Access to Biological Resources), certified according to ISO 9001 and NFS 96-900 respectively. More than 134,000 samples and their associated bioclinical data (including vaccination status, ethno-geographic background, medical history including chronic inflammatory disease or allergy) and environmental factors (lifestyle, international travel), microbial environment, dietary, exposure to stress or pollutants ...) are collected routinely.

The Diagmicoll cohort collects bio-resources from healthy volunteers, mainly to enable National Reference Centers to optimize and develop new diagnostic methods.

The CoSImmGEn cohort was set up to meet more complex needs such as the longitudinal monitoring of the immune system, as well as other integrative systems (eg metabolism / endocrine system, neurocognitive system...), by integrating the genetic and environmental data.

In addition to these two cohorts open to the scientific community, other "closed" collections have been developed to support projects focused on a given pathology: the WHO biobank on African Human Trypanosomiasis ("sleeping sickness"), the cohort on Verneuil disease (or hidradenitis suppurativa) followed at the IP Medical Center, a Cameroonian cohort for studying mother-to-child transmission of HIV, the DyPAVIR cohort studying vaginal and oral papillomavirus infections in France, the National Listeria and Listeriosis Surveillance Survey (MONALISA), the Tick-borne Disease Study Cohort (OHTICKS), the Environmental Pediatric Enteropathy in Africa Study (AFRIBIOTA) and the discovery of new pathogens in infectiology (Pathodisc / PATHO-HTS) or oncology (INECOC). Another project (Opiodyn) aimed to characterize opiorphine, a new anti-nociceptive molecule.


The mission of the ICAReB platform is to support cohorts of volunteers and biobanking activities and is governed by a Charter.
In practice, it provides 2 main activities:

• Support cohorts of healthy volunteers and patients: if you are willing to join one of these cohorts, you can download our flyer

• Establishment or reception, conservation and distribution of collections of biological resources (samples & associated data) of human origin for scientific research purposes.


The ICAReB platform is an internship site for FIEC and in the management of biobanks at ESTBB.




The ICAReB platform is part of:

• National network 3CR
• National infrastructure BIOBANQUES (reference as BB-0033-00062)
• Pan-European BBMRI infrastructure (reference as AO 203)
• Society ESBB for biopréservation and biobanking (reference as Bio 056)
• From PIBNet (Pasteur International Bioresources Network)
WHO's collaborateurs



Statistics (Indicators)

Extract of the ICAReB Scientific Committee (CoSciB) Annual Report 2018.


Icareb statistics
Icareb statistics
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