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News | 2022.12.07
SpikImm receives a major funding to accelerate the clinical and industrial development of its monoclonal antibodies against SARS-CoV-2
SpikImm, a biotech company founded in 2021 by Truffle Capital in collaboration with the Institut Pasteur, has been awarded a €15 million non-dilutive financing from the French governmentFrance 2030 program for its "PROPHYMAB" project, which is supported as part of the "Emerging Infectious Diseases and CBRN Threats" Acceleration Strategy. SPK001, the first treatment candidate (...
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Fiche maladie | 2022.01.11
Chlamydia
Chlamydia is a sexually transmitted infection (STI) caused by the bacterium Chlamydia trachomatis. It is the most widespread bacterial STI, affecting both men and women, and is particularly common among young people. In many cases, infection is asymptomatic and is therefore not diagnosed or treated, which contributes to its spread. Chlamydia can be contracted several times, since acquired...
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News | 2023.05.04
Chikungunya: how the tiger mosquito helps the virus cross borders
The tiger mosquito, which is native to Southeast Asia, is set to continue to spread to temperate regions and pose a major public health problem. Researchers at the Institut Pasteur have shown that this mosquito has acquired the ability to transmit the chikungunya virus as effectively at 20°C as at 28°C.
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Portrait | 2023.02.10
Caroline Demangel – an ambitious and enterprising scientist
Finding her path, making meaningful choices and daring to take the initiative – these are the principles that have guided Caroline Demangel through her career. In the demanding and competitive field of science, she has trusted her aspirations and risen to new challenges. In 2021, the scientist and her team revealed a new therapeutic target for bone marrow cancer.
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Article | 2019.06.25
Pathogen genomics and microbiota (8 entities)
Research in this thematic area explores the genomes of infectious agents in relation with their evolution. It also investigates the regulation of the microbiota composition and the mechanisms by which microbiota dysbiosis influences antimicrobial immunity.
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Article | 2019.06.18
Transversal
Teams from the Department of Structural Biology and Chemistry and from Computational Biology develop new molecules, technologies and approaches to detect and fight AMR.
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Document de presse | 2017.10.12
Five Institut Pasteur scientists receive 2017 L'Oréal-UNESCO "For Women in Science" Fellowships
On October 11, 2017, five young scientists at the Institut Pasteur received 2017 L'Oréal-UNESCO "For Women in Science" Fellowships. Through their research, the three postdoctoral fellows and two PhD students are helping to advance scientific knowledge in the fields of child malnutrition, the immune system, vaccination, emerging diseases and psychotic disorders. These fellowships, awarded to...
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Document de presse | 2014.04.09
Chikungunya raises concern in the Americas
Despite the presence of potentially susceptible mosquitoes, the first autochthonous cases of chikungunya on the American continent were not reported until December 2013 when a severe epidemic struck the West Indies. In order to assess the risks of the virus being transmitted and spreading throughout the territory, scientists from the Institut Pasteur and Fiocruz (Brazil) undertook the most...
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Document de presse | 2014.10.13
Human papillomavirus linked to auto-immune disease
Erosive oral lichen planus (OLP) is an auto-immune disease affecting skin and mucous membranes which results in an abnormal immune response against mucocutaneous cells. Today, scientists at the Institut Pasteur, Inserm, Paul Sabatier University (Toulouse) and the CNRS have proven that the immune cells involved in OLP are the same as those activated during an immune response to human...
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Document de presse | 2010.12.01
Identification of the 3D structure of chikungunya virus surface proteins
Researchers at the Institut Pasteur and CNRS, in collaboration with the Synchrotron SOLEIL, have solved the three-dimensional atomic structure of the glycoproteins that envelop the chikungunya virus. This discovery helps to understand how this protein complex is activated in order for the virus to invade target cells. Activation is a key stage in the viral life cycle and understanding its...