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Document de presse | 2020.10.08
AIDS: Furthering Knowledge of Natural HIV Infection Control Mechanisms
A further step has just been taken in understanding the mechanisms that allow some individuals to control HIV infection without treatment.A research team led by Dr. Asier Sáez-Cirión (Institut Pasteur) and Dr. Bruno Vaslin (IDMIT[1], CEA-Inserm-Université Paris Saclay) observed for the first time that the antiviral activity of CD8+ T cells of "controller" macaques infected with the simian...
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Document de presse | 2021.03.07
COVID-19: neutralizing immune response lasts longer in women than in men
As part of the SEROCoV-HUS study, teams from Strasbourg University Hospital and the Institut Pasteur monitored 308 hospital staff who had previously contracted a mild form of SARS-CoV-2. The scientists demonstrated that neutralizing antibodies could be detected in 84% of them up to 6 months after infection, but that the level fell more quickly in men than in women. These results seem to suggest...
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News | 2021.03.09
Whooping cough: light shed on the entry mechanism of a key Bordetella pertussis virulence factor
Bordetella pertussis is the agent responsible for whooping cough, a disease that is currently on the rise. In particular, the bacterium produces the CyaA toxin. A consortium including several teams from the Institut Pasteur, CNRS, and Sorbonne University, working closely with the C2RT Proteins Pole technical cores and several SOLEIL and ESRF synchrotron light lines, has examined the entry...
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Document de presse | 2021.04.21
SARS-CoV-2: infection induces antibodies capable of killing infected cells regardless of disease severity
Drawing on epidemiological field studies and the FrenchCOVID hospital cohort coordinated by Inserm, teams from the Institut Pasteur, the CNRS and the Vaccine Research Institute (VRI, Inserm/University Paris-Est Créteil) studied the antibodies induced in individuals with asymptomatic or symptomatic SARS-CoV-2 infection. The scientists demonstrated that infection induces polyfunctional antibodies....
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News | 2021.07.09
The Institut Pasteur International Network is evolving and becoming the Pasteur Network
A new system of governance is being introduced for the Institut Pasteur International Network and its 33 members, which since 2011 have been part of the Pasteur International Network association, which was chaired by the Institut Pasteur President Stewart Cole. Ten years on, the Network is adopting a more participatory, balanced mode of governance and a more structured business model. The...
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News | 2021.07.15
BCG vaccine: the first tuberculosis vaccination took place a century ago
July 2021 marks the hundredth anniversary of the first vaccination of an infant with the BCG vaccine. Although tuberculosis is still one of the ten leading causes of mortality worldwide, this vaccine, developed at the Institut Pasteur, led to a steep reduction in the number of cases. We take a look back at how the vaccine was discovered.Albert Calmette arrived in Lille in 1897 as director of the...
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News | 2021.12.14
2022: the bicentenary of Louis Pasteur's birth
Louis Pasteur was born on December 27, 1822. He was an international figure in scientific and medical research and the founder of the Institut Pasteur (Paris) in 1887. Louis Pasteur was a precursor of a certain way of conducting research, deeply concerned with its goals, both humanistic and universal, and the need to train and transmit this approach and these values to future generations. Today,...
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Document de presse | 2022.06.07
Institut Pasteur and MSDAVENIR sign a partnership to improve strategies for controlling the spread of vector-borne viral diseases like Zika
The Institut Pasteur and MSDAVENIR, a health research endowment fund by MSD, signed an important partnership to anticipate responses to future vector-borne viral epidemics today. The partnership, worth more than €1.7 million, will support the INTRANZIGEANT project led by Dr. Louis Lambrechts, head of the Virus-Insect Interactions Unit, and Xavier Montagutelli, head of the Mouse Genetics...
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News | 2022.07.11
How ‘death’ molecules squeeze the cells out of our tissues
Most of our tissues are constantly renewed and needs to get rid of dying cells without affecting their organisation. A newly identified mechanism is responsible for the seamless exclusion of dying cells from our tissues. This process is based on the dismantling of microtubules, long fibers well known for their function during cell division and transport in the cells. Tuning microtubules stability...
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Document de presse | 2022.12.20
Identification of a new neural pathway essential for refining odor perception
In the brain, sensory messages are processed by neurons that send the information collected by the sensory organ to the different structures of the brain. At each stage of integration, the activity of these neurons is controlled by interneurons that exert local inhibition in order to direct and modulate the neural messages. This type of circuit forms the classical architecture of the sensory...