-
Document de presse | 2023.03.28
COVID-19: How is it spreading in households?
More than three years after the start of the COVID-19 epidemic, mathematical modeling is still providing us with valuable insights, as shown in a recent study on household transmission of SARS-CoV-2 by the Hong Kong University School of Public Health and the Institut Pasteur/Université Paris Cité. Scientists believe that there is a subset of individuals with SARS-CoV-2 who are three times more...
-
News | 2019.09.26
A tobacco-dependence gene responsible for alcohol dependence
A series of human genome-wide studies have revealed a strong correlation between a chromosomal locus and the risk of developing tobacco dependence. One mutation has been identified in particular (rs16969968, or SNPα5). Studies have investigated whether this mutation is also associated with alcoholism, given the known high comorbidity between tobacco and alcohol addiction. A team from the Institut...
-
Document de presse | 2019.11.12
Gut microbiota imbalance promotes the onset of colorectal cancer
The gastroenterology team at Henri-Mondor AP-HP Hospital and University Paris-Est Créteil, led by Professor Iradj Sobhani, together with teams from Inserm and the Institut Pasteur Molecular Microbial Pathogenesis Unit (U1202), led by Professor Philippe Sansonetti – holder of the Microbiology and Infectious Diseases Chair at the Collège de France –, have demonstrated that an imbalance in the gut...
-
Fiche maladie | 2019.10.02
Influenza
Influenza is a contagious respiratory infection caused by influenza viruses, which are unique due to their vast genetic variability. It is a public health issue because of the seasonal outbreaks that affect 2 to 6 million people in France every winter, with influenza-associated excess mortality estimated at approximately 10,000 deaths, mainly in vulnerable individuals. The pandemic risk...
-
Document de presse | 2021.03.07
COVID-19: neutralizing immune response lasts longer in women than in men
As part of the SEROCoV-HUS study, teams from Strasbourg University Hospital and the Institut Pasteur monitored 308 hospital staff who had previously contracted a mild form of SARS-CoV-2. The scientists demonstrated that neutralizing antibodies could be detected in 84% of them up to 6 months after infection, but that the level fell more quickly in men than in women. These results seem to suggest...
-
Document de presse | 2021.12.10
COVID-19 patients in ICUs: Study reveals an increased risk of invasive fungal secondary infections
What if certain fungi exacerbate respiratory distress in individuals with covid-19? The mycovid study published in the lancet respiratory medicine yields its initial results. Teams at Rennes University Hospital – University of Rennes 1, Necker-Enfants Malades Hospital (part of the Paris Public Hospital Network or AP-HP), Georges-Pompidou European Hospital (AP-HP) – Université de Paris, Avicenne...
-
News | 2023.01.30
Hepatitis B: towards better treatment for infected individuals in Africa
With 82 million people currently infected in Africa, the hepatitis B virus represents a major health threat. Early treatment can considerably reduce the risk of complications associated with the disease. In a recent analysis, scientists challenged the suitability of the diagnostic tests used in sub-Saharan Africa and called for more optimized treatment for local populations.
-
Document de presse | 2023.03.15
Emergence of extensively drug-resistant Shigella sonnei strain in France
Shigellosis, a highly contagious diarrheal disease, is caused by Shigella bacteria circulating in industrializing countries but also in industrialized countries. Scientists from the French National Reference Center for Escherichia coli, Shigella and Salmonella at the Institut Pasteur who have been monitoring Shigella in France for several years have detected the emergence of extensively drug-...
-
Document de presse | 2023.10.19
Genes fuelling antibiotic resistance in Yemen cholera outbreak uncovered
An international collaborative research effort involving scientists from the Wellcome Sanger Institute, the University of Toronto, the Institut Pasteur and Sana'a University has revealed the source of antibiotic resistance that emerged in bacteria driving the cholera outbreak that is currently affecting Yemen. The results of their research, published on September 28, 2023 in the journal Nature...
-
Article | 2020.03.27
Coronavirus (Covid-19) research projects
VACCINE CANDIDATES1. Development of an animal model and accelerated development of a DNA vaccine candidate(SCARD SARS-CoV-2 project)Aims:To develop a mouse model of SARS-CoV-2 infection.This will not only enable us to evaluate the efficacy of the vaccine; it will also facilitate in vivo research on SARS-CoV-2. To evaluate the immunogenicity (ability to induce a specific immune reaction) and...