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Document de presse | 2020.10.15
Innate immunity and fusion of cells infected with SARS-CoV-2
Innate immunity is the fastest-acting component of the immune system, but so far little is known about its role during infection with SARS-CoV-2. A few hours after an infection, the body emits an alarm signal, interferon, enabling cells that have not yet been infected to produce antiviral proteins. This phenomenon occurs well before the production of neutralizing antibodies. Scientists from the...
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Document de presse | 2021.07.21
SARS-CoV-2 damages ciliated cells and inhibits mucociliary clearance in the airways
COVID-19 is a viral disease with respiratory symptoms that can induce fatal pneumonia. Understanding how SARS-CoV-2 spreads in the respiratory tract can help scientists identify the parameters controlling the severity of infection. Scientists from the Institut Pasteur, the CNRS and Inserm found that SARS-CoV-2 multiplies efficiently in the respiratory tract, and that it primarily targets ciliated...
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Document de presse | 2021.09.27
SARS-CoV-2: different immune responses observed in nasal mucosa and blood
The clinical manifestations of SARS-CoV-2 infection vary from one individual to the next, and much remains unknown about the mechanisms underpinning this variability. Since the nasal mucosa is one of the first entry points of the virus, scientists from the Institut Pasteur and Inserm, in collaboration with Cochin AP-HP Hospital, analyzed in parallel the immune responses in the nasal mucosa and in...
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News | 2020.05.20
Blood test: a potential new tool for controlling infections
A new technique could provide vital information about a community’s immunity to infectious diseases including malaria and Covid-19.The diagnostic test analyses a blood sample to reveal immune markers that indicate whether – and when – a person was exposed to an infection. It was developed to track malaria infections in communities, to assist in the elimination of deadly ‘relapsing’ malaria, but...
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Document de presse | 2023.08.09
SARS-CoV-2: how the history of human populations influences their immune response
During the COVID-19 pandemic, the clinical spectrum observed among people infected with SARS-CoV-2 ranged from asymptomatic carriage to death. Researchers at the Institut Pasteur, the CNRS and the Collège de France, in collaboration with researchers around the world1 , have investigated the extent and drivers of differences in immune responses to SARS-CoV-2 across populations from Central Africa...
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Document de presse | 2021.07.16
ComCor study: analysis of the effectiveness of messenger RNA vaccines against the SARS-CoV-2 Alpha and Beta variants in France
Over the past six months, the World Health Organization has categorized four SARS-CoV-2 variants as being "of concern" because they are more transmissible or may escape the immune response. They have been termed the Alpha, Beta, Gamma and Delta variants. Scientists from the Institut Pasteur, in collaboration with the French National Health Insurance Fund (CNAM), Ipsos and Santé publique France,...
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Document de presse | 2024.03.28
Inauguration in Brazil of the Institut Pasteur de São Paulo, member of the Pasteur Network
On March 27, 2024, the Institut Pasteur de São Paulo was inaugurated by French President, Emmanuel Macron. As a member of the Pasteur Network, this institute, founded by the Institut Pasteur and the University of São Paulo, conducts international-level research in the field of health biology to further understanding of diseases and their impact on human health, especially in the context of...
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News | 2020.02.27
Foreign travel – a tonic for the health?
All travelers can come into contact with health risks that are completely different from those they generally encounter on a daily basis. So it is vital to prepare thoroughly for any trip – and that involves consulting a specialist travel clinic such as the Institut Pasteur Medical Center (CMIP).Travel is a formative experience for young people – and young people often take a casual attitude to...
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Document de presse | 2021.04.21
SARS-CoV-2: infection induces antibodies capable of killing infected cells regardless of disease severity
Drawing on epidemiological field studies and the FrenchCOVID hospital cohort coordinated by Inserm, teams from the Institut Pasteur, the CNRS and the Vaccine Research Institute (VRI, Inserm/University Paris-Est Créteil) studied the antibodies induced in individuals with asymptomatic or symptomatic SARS-CoV-2 infection. The scientists demonstrated that infection induces polyfunctional antibodies....
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Document de presse | 2021.12.01
Virus related to SARS-CoV-2 found in bats in Cambodia
What are the origins of SARS-CoV-2? This is the world’s most pressing scientific puzzle. Its pieces scattered throughout the world are currently being sought out by scientists. Their goal: to track down the culprit for the largest health crisis to hit the globe in the past century. Scientists at the Institut Pasteur in Paris and the Institut Pasteur du Cambodge have identified a coronavirus in...
