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Article | 2019.05.21
Emerging infectious diseases
Ever since its very early days, the Institut Pasteur has been committed to tackling emerging infections, and its work has left an extraordinary legacy. Many emerging infectious diseases are zoonoses, in which an animal pathogen has crossed the species barrier to cause disease in humans.
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Document de presse | 2021.05.28
COVID-19: analysis of the sensitivity of the Delta variant to monoclonal antibodies and sera from convalescent and vaccinated individuals
The Delta variant was detected for the first time in India in October 2020 and has since spread throughout the world. It is now dominant in many countries and regions (India, the UK, Portugal, Russia, etc.) and is predicted to be the most prevalent variant in Europe within weeks or months. Epidemiological studies have shown that the Delta variant is more transmissible than other variants....
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Article | 2020.03.27
Coronavirus (Covid-19) research projects
VACCINE CANDIDATES1. Development of an animal model and accelerated development of a DNA vaccine candidate(SCARD SARS-CoV-2 project)Aims:To develop a mouse model of SARS-CoV-2 infection.This will not only enable us to evaluate the efficacy of the vaccine; it will also facilitate in vivo research on SARS-CoV-2. To evaluate the immunogenicity (ability to induce a specific immune reaction) and...
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Fiche maladie | 2015.10.06
Viral hepatitis
Hepatitis is an inflammation of the liver caused by toxic substances or – in the majority of cases – by viruses. To date, five viruses have been identified that target the liver and cause inflammatory infection. These viruses are referred to by the letters A, B, C, D and E, and vary according to their transmission mode (fecal-oral for A and E, parenteral for B and C) and their aggressive profile.
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Fiche maladie | 2017.04.24
Antibiotic resistance
Antibiotics are drugs used to treat infections caused by bacteria. Antibiotic resistance occurs when bacteria become resistant and no longer respond to these drugs.
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Fiche maladie | 2015.10.06
Avian influenza
The term avian influenza actually refers to several entities. First, it indicates infection with an influenza type A virus in birds. This infection can take various forms. Certain viruses are responsible for outbreaks in domestic poultry, with a very high fatality rate. These episodes, previously identified as "fowl plague," are now known as avian influenza (or "bird flu"). Human infection with a...
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Document de presse | 2016.06.23
Antibodies that are effective against both dengue and Zika viruses
Scientists from the Institut Pasteur and the CNRS[1], in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. The description of the binding site for these antibodies on the viral envelope, identical for both viruses, could lead to the development of a universal...
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Document de presse | 2015.06.24
Three Ebola virus variants identified in Guinea
Sequencing the genome of Ebola virus strains circulating in Guinea has allowed scientists at the Institut Pasteur in Dakar and in Paris, the CNRS and the University of Sydney to retrace the spread of the virus and monitor its evolution in the country where the outbreak started. This research reveals the co-circulation in Guinea, particularly in the urban regions of the capital and neighboring...
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Document de presse | 2015.11.10
Dengue: asymptomatic people transmit the virus to mosquitoes
Scientists at the Institut Pasteur in Cambodia, the Institut Pasteur in Paris and the CNRS provided proof that people infected by dengue virus but showing no clinical symptoms can actually infect mosquitoes that bite them. It appears that these asymptomatic people – who, together with mildly symptomatic patients, represent three-quarters of all dengue infections – could be involved in...
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Document de presse | 2014.06.11
Predicting mutations that lead to epidemics
Using the 2005-2006 chikungunya virus epidemic that occurred in the Indian Ocean islands as a study model, researchers at the Pasteur Institute have succeeded in developing an approach that can predict the virus mutations most likely to emerge in the short-term, with strong epidemic potential. This work has strong implications for improving surveillance of ongoing epidemics and the potential to...