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News | 2016.02.14
Birdy: assessing the impact of resistant bacterial infections in young children
The research program BIRDY is focused on bacterial infections, including resistant, in small children. On the occasion of the publication in The Lancet of a correspondence calling for accelerated efforts in research and public health in the fight against neonatal bacterial infection and antibiotic resistance in low-income countries, Dr. Awa Ndir, epidemiologist at the ...
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News | 2016.03.10
Unmasking an ancestral mechanism of integrons — key players in antibiotic resistance
With the ultimate aim of combating antibiotic resistance acquired by bacteria during evolution, researchers from the Institut Pasteur and CNRS have managed to shed light on one of the mechanisms of DNA recombination in bacteria.Resistance genes are transferred between pathogenic bacteria via different pathways, but always as a single strand of DNA. One of the main players in these transfers is...
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Document de presse | 2016.04.11
Malaria: a new route of access to the heart of the parasite
Scientists have just identified an Achilles heel in the parasite that causes malaria, by showing that its optimum development is dependent on its ability to expropriate RNA molecules in infected cells – a host-pathogen interaction that had never previously been observed. Although the precise function of this deviation remains mysterious, these findings open new perspectives for the targeted...
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Fiche maladie | 2016.06.21
Zika
The Zika virus is a flavivirus transmitted by mosquitoes of the Aedes genus. It is widespread in Asia and Africa and has recently emerged in Central and South America. The disease caused by the virus develops 3 to 12 days after the vector insect bite and symptoms (which resemble those of the dengue virus or chikungunya, also spread by the same mosquito) include fever, headaches, skin rash,...
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News | 2016.06.22
Antibodies that are effective against both dengue and Zika viruses
Scientists have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. The description of the binding site for these antibodies on the viral envelope, identical for both viruses, could lead to the development of a universal vaccine that offers simultaneous protection against dengue and Zika virus disease.
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Document de presse | 2016.06.23
Antibodies that are effective against both dengue and Zika viruses
Scientists from the Institut Pasteur and the CNRS[1], in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. The description of the binding site for these antibodies on the viral envelope, identical for both viruses, could lead to the development of a universal...
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News | 2016.08.03
A mobile laboratory recreated the scenario of an emerging epidemic in the heart of the Institut Pasteur
Men in white bunny suits are working under tents at the back of the Institut Pasteur historical greenhouse. This image, that is not uncommon to see on epidemic ground, is surprising in the heart of Paris.In fact, 12 scientists and technicians from 6 Western Africa countries were participating in an exercise recreating the scenario of a possible emerging epidemic. For this, a mobile laboratory was...
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News | 2016.08.10
Disturbing prevalence of antibiotic-resistant Enterobacteriaceae in Central African children
Nearly 59% of Central African children under 5 years, are asymptomatic carriers of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E); one of the highest prevalence ever described in the world. These bacteria are resistant to every antibiotics currently marketed in Central African Republic.Alain Farra, Thierry Frank and Sébastien Breurec (1), from Bacteriology Laboratory at the...
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News | 2016.08.22
TONIRA : towards better medical care of acute respiratory infections among children in Niger
In Niger, respiratory infections and pneumonia are the second cause of hospital infant mortality (10 to 20% of deaths according to health authorities information). As in most African countries, few data on surveillance and etiology of these infections are available whereas they are essential to guide public health policies. In addition in Niger, antibiotic treatment for acute respiratory diseases...
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News | 2016.09.22
Culex mosquitoes do not transmit Zika virus
Since the first cases of infection were identified in Brazil, in May 2015, the Zika virus has spread to over 46 countries in America. Several hypothesis are discussed to explain the extent of the epidemic and the rapidity with which the virus has invaded the continent. The transmission could be facilitated by the absence of immunity of the American populations as the virus comes from Africa but...