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Article | 2020.06.16
Development of simple Covid-19 serological tools and targeted serosurvey of at-risk individuals
Aim: to develop simple serological tools that can be used to establish three tests: an enzyme-linked immunosorbent assay (ELISA), an immunofluorescence assay (IFA) and multiplex microsphere-based immunoassays (MIAs – capable of detecting several targets). This research will pave the way for the serological investigation of at-risk individuals such as those working at animal markets, farmers...
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Article | 2020.06.16
Red Cross health workers and volunteers and continuity of care with COVID-19: an operational approach using mixed methods
Aim: to study social and cultural challenges encountered by French Red Cross health workers and volunteers (who work with healthcare facilities/hospitals, nursing homes, etc. as well as those working in the field to assist migrants, homeless people, and frail and elderly people) and monitor communication in mainstream and social media to adapt the response to the pandemic in each region. By...
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Report | 2021.02.22
SARS-CoV-2, COVID-19 epidemic: the Institut Pasteur's response, scientific research and discoveries in 2020
The Institut Pasteur is one of the world's leading centers for research on infectious diseases. This area is therefore one of the priority research areas of its 2019-2023 strategic plan. On January 27, 2020, a 'coronavirus task force' was set up to respond to the urgency of this health crisis, by studying the virus and the disease it causes - the task force was created at a time when the 11...
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Document de presse | 2021.03.26
COVID-19: analysis of the sensitivity of the UK (B.1.1.7) and South African (B.1.351) variants to SARS-CoV-2 neutralizing antibodies
The B.1.1.7 and B.1.351 variants of SARS-CoV-2 were first detected in the UK and South Africa respectively, and have since spread to many other countries. Scientists from the Institut Pasteur joined forces with Orléans Regional Hospital, Tours University Hospital, Créteil Intercommunal Hospital, Strasbourg University Hospital and Georges Pompidou European Hospital to study the sensitivity of...
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News | 2024.06.11
Strengthening Multisectoral and Regional Cooperation to Mitigate Vector-Borne Diseases in the Mediterranean
The interconnectedness of our world has brought about significant challenges in public health, particularly with the rise of infectious epidemics. Globalization, climate change, and rapid urbanization have created fertile ground for the emergence and spread of diseases, as starkly illustrated by the COVID-19 pandemic. Among these threats, vector-borne diseases transmitted by mosquitoes and ticks...
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Document de presse | 2023.11.14
Significant "post-COVID" resurgence in invasive meningococcal disease
A team of scientists from the Institut Pasteur has used the database of the National Reference Center for Meningococci to trace the evolution of invasive meningococcal disease cases in France between 2015 and 2022, revealing an unprecedented resurgence in the disease after the easing of control measures imposed during the COVID-19 epidemic. Recently reported cases have mainly been caused by...
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News | 2022.05.12
SARS-CoV 2: A booster with a "Lenti-COVID" vaccine candidate induces protective immunity in the respiratory mucosa in a preclinical model
Scientist at the Institut Pasteur- TheraVectys Joint Laboratory have demonstrated the efficacy of their lentiviral candidate vaccine “Lenti-COVID”, administered as an intranasal booster dose six months after primary vaccination with a messenger RNA vaccine, in a pre-clinical model. This intranasal booster induces protective immunity in the respiratory mucosa. These results pave the way for...
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Article | 2020.06.22
Nicotinic modulation of SARS-CoV-2 infection in the brain
Aim: This project aims at experimentally testing the hypothesis that the nicotinic acetylcholine receptor (nAChR) plays a key role in the pathophysiology of Covid-19 infection and might represent a target for the prevention and control of Covid-19 infection.
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Document de presse | 2022.12.19
Modelling has evaluated the role of antiviral treatment and vaccination in exiting the Zero-COVID strategy in Wallis and Futuna
By June 2022, the Wallis and Futuna Islands, a French overseas territory, had successfully implemented a Zero-COVID strategy that significantly reduced the number of SARS-CoV-2 infections. From mid-June 2022, a gradual reopening of the borders was planned. However, the relatively low immunity in the population (due to limited vaccination coverage and the number of previous infections) and the...
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Article | 2020.06.22
Evaluation of clinical presentation and evolution of SARS -CoV-2 coronavirus infection in Senegal
Aim: The overall objective of this study is to understand the main clinical, biological, virologic and immunological characteristics of Covid-19 cases detected in Senegal in order to inform the development and updating of health guidelines for cases management and reduce the potential impact of infection. A retrospective and prospective cohort study of Covid-19 confirmed cases will be...
