Pathogen biology (12 entities)

In addition to causing many infectious diseases, pathogens provide insightful information on fundamental biological processes. Research in this thematic area investigates the mechanisms underpinning the virulence of pathogens of global public health and/or veterinary concern.

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Pedro Alzari - Structural Microbiology

Mycobacterium Tuberculosis; Protein Structure; Bacterial Enzymes; Anti-microbial Resistance

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Frédéric Barras - Stress Adaptation and Metabolism in Enterobacteria

Iron/Sulfur Proteins; Fatty Acids; Bioenergetics; Gram-negative Bacteria; Antibiotics; Stress Responses

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Philippe Bastin - Trypanosome Cell Biology

Trypanosomes; Sleeping Sickness; Flagellum; Ciliopathies; Cell Imaging

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Ivo Gomperts Boneca - Biology and Genetics of Bacterial Cell Wall

Bacterial Cell Wall; Peptidoglycan; Antibiotic Resistance; Helicobacter Pylori - Induced Gastric Cancer;  Crohn’s Disease; Chronic Inflammation

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Hilde de Reuse - Helicobacter Pathogenesis

Helicobacter Pylori ; Virulence Factors; Peptic Ulcers; Gastric Cancer; Antibiotic Resistance; Metallobiology

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Bruno Dupuy - Pathogenesis of Bacterial Anaerobes

Anaerobic Bacteria; Clostridium difficile; Nosocomial Infection; Antibiotic-associated-diarrhoea; Microbiota; Metabolism and Stress

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Jean-Marc Ghigo - Genetics of Biofilms

Bacterial Biofilm; Antibiotic Resistance; Stress Resistance; Bacterial Interference; Genetics

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Lucy Glover - Trypanosome Molecular Biology

Human African Trypanosomiasis (HAT); Trypanosoma brucei; Antigenic Variation; DNA Repair; Variant Surface Glycoprotein (VSG)

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Guilhem Janbon - RNA Biology of Fungal Pathogens

Human Fungal Pathogens; Cryptococcus neoformans; Intron Dependent Gene Regulation; Long Non-coding RNAs; Genetics; Extracellular vesicles

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Giulia Manina - Microbial Individuality and Infection

Tuberculosis; Mycobacterium Tuberculosis; Bacterial Cell-to-cell Heterogeneity; Bacterial Quiescence; Bacterial Persistence

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Patrick Trieu-Cuot - Biology of Gram-Positive Pathogens

Gram-positive Bacteria; Streptococcus agalactiae; Staphylococcus aureus; Streptoccus gallolyticus; Metabolism Virulence

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Sven van Teeffelen - Microbial Morphogenesis and Growth

Bacterial Shape; Bacterial Growth; Bacterial Size; Cell-wall Expansion; Single-cell Physiology

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