First gene therapy trial in France to treat childhood deafness
The Audiogene trial aims to correct the deficiency in a gene responsible for congenital deafness to restore hearing, using pioneering research conducted at the Institut Pasteur.
A malaria vaccine that blocks infection
Malaria remains a major public health threat in tropical countries. A vaccine against the parasite Plasmodium vivax proves effective in limiting blood-stage infection.
Immunotherapy: new mechanism of action of anti-PD1 antibodies
These antibodies, injected into the bloodstream, do not just act on the tumor; they also act on the lymph nodes, where many immune responses begin, raising hopes for more effective cancer treatments.
Monoclonal antibody effective in preventing severe bronchiolitis cases
A study by the Institut Pasteur and Santé publique France demonstrates the efficacy of nirsevimab as a preventive measure against bronchiolitis in infants.
Knowing Indian Ocean surface temperature can help anticipate dengue outbreaks
This approach could be used to improve predictions about the magnitude of dengue outbreaks several months in advance. The indicator, based on temperature fluctuations at the surface of the Indian Ocean, can also be used for any other world region.
Institut Pasteur actively involved in Paris 2024 Olympic and Paralympic Games
After demonstrating prior to the event that the tiger mosquito is capable of transmitting several diseases in the Greater Paris region, the Institut Pasteur plays a key role in safeguarding public health and safety at the 2024 Olympic and Paralympic Games. Several staff members are also involved in the Games as participants, volunteers or torch bearers!
Technological breakthrough in microbiome gene editing
The startup Eligo Bioscience – co-founded by Institut Pasteur laboratory head David Bikard, who is also the company’s scientific advisor – successfully edits the DNA of microbiome bacteria directly in the gut of a mouse model.
Institut Pasteur explains the resurgence of whooping cough in France in 2024
Genomic analysis of 70 bacterial isolates gives scientists a better understanding of the largest whooping cough outbreak in France for at least 25 years.
First long-term remission from HIV infection observed after a bone marrow transplant
Romuald, the “Geneva patient”, is the only patient to experience HIV remission after receiving a bone marrow transplant without the CCR5-delta 32 mutation, known to make CD4 cells resistant to the virus.
Key gene drives early embryonic development
The Institut Pasteur discovers the crucial role of the gene NR5A2 in the first stages of embryonic development in mammals. In the absence of this gene, the embryo stops developing a few days after fertilization. This research sheds new light on a biological process that is not yet fully understood.
Artificial intelligence used to select phages, a targeted alternative to antibiotics
Scientists develop an AI model capable of making a tailored selection of phages by analyzing the genome of targeted bacteria.
