populations genetics
News
2021.05.31
Diphtheria is a severe infection caused in humans by toxigenic strains of Corynebacterium diphtheriae bacteria. If left untreated, it leads to death in 5 to 25...
News
2021.06.01
The structure of DNA and chromosomes is a major focus of research, but still holds a number of mysteries. Scientists from the Institut Pasteur and the CNRS...
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2021.05.21
Dominant optic atrophy (DOA) is one of the most common forms of mitochondrial disease. It can be caused by genetic mutations in OPA1 resulting in mitochondrial...
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2020.08.04
Resistance to artemisinin, the main component of current antimalarial treatments recommended by WHO, is widespread in South-East Asia, but has not been...
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2021.02.22
The Lymphopoiesis Unit identified within the first cells that seed the thymus a unique population of lymphoid progenitors. These cells can generate lymphoid...
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2020.10.17
Ludovic Deriano’s Unit studied cells mutated for NHEJ, the canonical repair pathway for DNA double-strand break. The researchers showed that those transformed...
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2020.03.05
Cells in vivo organize into 3D structures that underlie the shape and mechanics of tissues, as well as their biological function. Researchers mapped how...
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2020.07.16
Triplet repeat expansions are responsible for more than two dozen neurological and developmental disorders. Shortening these repeats with endonucleases could...
News
2020.03.27
Replicative DNA polymerases have evolved the ability to copy the genome with high processivity and fidelity. In Eukarya and Archaea, their processivity is...
News
2021.04.30
It remains unclear whether and how neural stem cells (NSCs) are maintained at long-term in the vertebrate brain. Combining intravital imaging, genetic tracing...