-
Fiche maladie | 2015.10.06
West Nile
West Nile virus is transmitted to humans by mosquitoes. It causes sudden fever, sometimes associated with neurological complications that can be severe in many animal species. Since it was first identified in East Africa, the virus has been observed on every continent. It is currently endemic in the Mediterranean Basin, Central Europe and North America, where it is responsible for fatal human...
-
News | 2021.10.15
The Institut Pasteur de Guinée: a young institute in the midst of the COVID-19 crisis
The decision to set up an Institut Pasteur in Guinea was made in 2014 in response to the Ebola crisis. It reflects the joint determination of France and Guinea to tackle emerging outbreaks on a long-term basis for the welfare of the population. When the COVID-19 pandemic struck, how was this young institute able to fulfill its remit as a front-line laboratory?When the first case of COVID-19 was...
-
Document de presse | 2022.02.02
New anti-HIV antibody function discovered: tethering of viral particles at the surface of cells
Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1[1] antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures. The scientists found that certain antibodies already known for effectively targeting HIV-1 envelope (Env) protein can prevent infected cells from releasing viral particles...
-
Document de presse | 2022.03.29
SARS-CoV-2: neutralization of BA.1 and BA.2 by therapeutic monoclonal antibodies
The SARS-CoV-2 Omicron BA.1 sublineage has been supplanted in many countries by the BA.2 sublineage. Although Omicron is responsible for less severe forms in the general population, immunocompromised people are still at higher risk of developing severe forms of COVID-19. Several monoclonal antibodies are currently available in clinical practice as a preventive treatment for these patients....
-
Document de presse | 2022.04.12
HIV: The Antibodies of "Post-treatment Controllers"
A very small percentage of people with HIV-1, known as "post-treatment controllers" (PTCs), are able to control their infection after interrupting all antiretroviral therapy.Understanding the fundamental mechanisms that govern their immune response is essential in order to develop HIV-1 vaccines, novel therapeutic strategies to achieve remission, or both.A recent study investigated the humoral...
-
News | 2022.06.08
The role of social sciences in the response to an epidemic: the example of the COVID-19 pandemic
A lesser known but equally crucial dimension in managing and responding to an epidemic is social sciences in health, which can shed light on populations' understanding, perception and acceptance of the risks associated with diseases. The COVID-19 pandemic is no exception. As the disease spread across the planet, clear differences in perception by populations were observed in different countries,...
-
News | 2022.06.14
A New Drug Target against Malaria
Malaria is a disease that continues to cause tremendous suffering and mortality in the tropics. This disease is caused by Plasmodium parasites. The species Plasmodium falciparum causes the severest and most deadly form of malaria. Scientists from Institut Pasteur studied the blood stage of the parasites and found a mechanism which could lead to new and efficient drugs against Malaria.Despite...
-
Article | 2024.04.30
Edmond Nocard, discoverer of the Nocardia bacterium
Veterinarian and biologist, this disciple of Louis Pasteur pioneered the study of microbial animal diseases and is considered the founder of veterinary microbiology.
-
News | 2022.07.09
Conversation: capacity building to prepare for the future
Institut Pasteur Senior Executive Scientific Vice-President Christophe d'Enfert provides a brief, cross-disciplinary overview of 2021 covering capacity building, enhanced partnerships and future technologies.
-
Article | 2023.12.18
Interdisciplinary Training in Genomic Epidemiology and Public Health Bioinformatics
This interdisciplinary programme, funded by ECDC, combines lectures and practical sessions delivered by multiple host institutions in order to enhance surveillance, preparedness, and readiness to respond to outbreaks.