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Document de presse | 2012.02.09
Newly characterized dengue virus antibody shows promise
Research teams from the Institut Pasteur, the CNRS, and Inserm have recently characterized the structure and mechanism of action of an antibody that successfully neutralizes all four strains of the dengue virus in mice models. Their groundbreaking work represents major progress for research efforts that hope to develop an effective vaccine to combat this disease. This study was published February...
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Document de presse | 2007.07.12
Leptospirosis: the first virulence gene identified
Although leptospirosis is one of the so-called "neglected" diseases, it still causes some 500,000 severe cases in humans around the world each year and also comprises a veterinary problem. A century after the pathogenic agent that causes the disease was found, researchers at the Institut Pasteur have discovered a gene that is essential to the bacteria's virulence. Their work,...
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Document de presse | 2005.02.24
"The Sword and the Shield" - How bacteria develop their virulence by creating multiple variants
Researchers at Institut Pasteur and the French National Institute of Health and Medical Research (Inserm), in association with the Imperial College of London, recently explained why Shigella flexneri bacteria, which cause fatal dysenteries, have several variants (serotypes), thus optimizing their virulence. This discovery, published in Science, is essential to vaccine research as, in order to be...
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News | 2018.11.14
130 years ago, the Institut Pasteur opened its doors for the first time
The Institut Pasteur, set up following the success of the human rabies vaccination with funds from a public appeal launched by the French Academy of Sciences, was officially opened 130 years ago, on November 14, 1888, at a ceremony attended by the French President Sadi Carnot and several other prestigious guests. We look back on a day that "would go down in the history of medicine".*A huge crowd...
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News | 2018.12.17
WHO high-level meeting on preparedness in public health emergencies
On December 4th, The Institut Pasteur International Network (IPIN) participated in a high-level meeting on preparedness in public health emergencies and the challenges and opportunities in urban areas organized by World Health Organization (WHO) in Lyon.The objective of this conference was to identify gaps and challenges, to foster intersectoral and multidisciplinary collaboration (including a "...
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Article | 2020.06.16
Randomized trial of Covid-19 chemoprophylaxis in healthcare professionals
Objective: To determine whether a two months treatment with hydroxychloroquine (HCQ) or Lopinavir / ritonavir (LPV / r) reduces the incidence of symptomatic or asymptomatic infections with SARS-CoV-2, compared to their placebo, in healthcare professionals exposed to the virus.In the absence of specific antiviral treatment, particular attention must be paid to prevention. Individual protective...
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News | 2023.09.05
HIV-AIDS: broadly neutralizing antibodies, stars of the lab
Highly promising, broadly neutralizing antibodies can react with the vast majority of HIV particles to cause their destruction by the body. However, the latter would have to be able to produce equally effective antibodies...
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Document de presse | 2024.04.26
WHO and France convene high-level meeting to defeat meningitis
Paralympians join effort to tackle deadly diseaseGlobal leaders highlight the need to defeat meningitis – a leading cause of disability – at a high-level meeting co-hosted by the World Health Organization (WHO) and Government of France, under the High Patronage of Emmanuel Macron, President of the French Republic. The event is taking place on 26-27 April 2024 at the Institut Pasteur and is...
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Article | 2024.04.30
Émile Roux, savior of children
In 1878, Louis Pasteur was looking for a physician to help him study contagious diseases. His associate Émile Duclaux introduced him to a former student of his – Émile Roux – who quickly came into the orbit of the famous scientist. The young physician was 25, Pasteur was 56.
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News | 2021.10.18
The replay of the conference "COVID-19, Advances and Remaining Challenges" is available
For three days, worldwide specialists shared their views about the pandemic during a congress hosted by the Institut Pasteur. Their contributions are to be found online.