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Document de presse | 2021.07.16
ComCor study: analysis of the effectiveness of messenger RNA vaccines against the SARS-CoV-2 Alpha and Beta variants in France
Over the past six months, the World Health Organization has categorized four SARS-CoV-2 variants as being "of concern" because they are more transmissible or may escape the immune response. They have been termed the Alpha, Beta, Gamma and Delta variants. Scientists from the Institut Pasteur, in collaboration with the French National Health Insurance Fund (CNAM), Ipsos and Santé publique France,...
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Document de presse | 2021.09.21
Covid-19: study on the effectiveness of immune memory after mRNA vaccination to recognize variants of SARS-CoV-2
The teams from Henri-Mondor AP-HP hospital and Paris-Est Créteil University, Inserm, CNRS, University of Paris, within the Necker-Enfants Malades Institute, and the Institut Pasteur analyzed the capacity of the immune memory generated after mRNA vaccination to recognize and neutralize SARS-CoV-2 variants.This work, coordinated by Prof. Matthieu Mahévas, Dr Claude-Agnès Reynaud, Prof. Jean-Claude...
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Document de presse | 2020.04.16
Bill & Melinda Gates Medical Research Institute and the Institut Pasteur to Develop a Novel Vaccine Against Shigella
The Bill & Melinda Gates Medical Research Institute (Gates MRI) and the Institut Pasteur have entered into an exclusive collaboration and license agreement to jointly develop a quadrivalent synthetic carbohydrate-based conjugate vaccine against Shigella flexneri serotypes 2a, 3a, and 6 and Shigella sonnei. Gates MRI will have an exclusive license for manufacture and commercialization of...
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Document de presse | 2021.10.26
The intranasal lentiviral vaccine candidate (Lenti-S) protects brain and lung in a pre-clinical animal model
The SARS-CoV-2 virus, responsible for the COVID-19 pandemic, primarily targets the respiratory tract, but its ability to infect cells of the nervous system has also been largely reported. Indeed, the expression of the receptor of this virus, the Angiotensin Converting Enzyme 2 (ACE2), by neuronal and glial cells makes the brain susceptible to SARS-CoV-2. Moreover, neurological manifestations are...
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Document de presse | 2021.11.26
ComCor study: new results on places of infection with SARS-CoV-2 and analysis of the efficacy of messenger RNA vaccines against the Delta variant
From May 23 to August 13, 2021, the Institut Pasteur, in partnership with the French National Health Insurance Fund (CNAM), Santé publique France and the Ipsos institute, conducted the fourth part of the ComCor epidemiological study on circumstances and places of infection with the SARS-CoV-2 virus in France. The aim of the study was to identify the socio-demographic factors, places visited and...
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Document de presse | 2022.12.19
Modelling has evaluated the role of antiviral treatment and vaccination in exiting the Zero-COVID strategy in Wallis and Futuna
By June 2022, the Wallis and Futuna Islands, a French overseas territory, had successfully implemented a Zero-COVID strategy that significantly reduced the number of SARS-CoV-2 infections. From mid-June 2022, a gradual reopening of the borders was planned. However, the relatively low immunity in the population (due to limited vaccination coverage and the number of previous infections) and the...
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Fiche maladie | 2020.01.21
COVID-19 (SARS-CoV-2 virus)
The SARS-CoV-2 coronavirus, discovered in December 2019 in the province of Wuhan in China, is responsible for COVID-19. This highly contagious emerging infectious disease spreads by airborne transmission and surface contamination. Although COVID-19 can be asymptomatic, it can also cause a variety of symptoms, including severe respiratory distress that may prove fatal. Vaccination and basic health...
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Fiche maladie | 2019.10.02
Influenza
Influenza is a contagious respiratory infection caused by influenza viruses, which are unique due to their vast genetic variability. It is a public health issue because of the seasonal outbreaks that affect 2 to 6 million people in France every winter, with influenza-associated excess mortality estimated at approximately 10,000 deaths, mainly in vulnerable individuals. The pandemic risk...
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News | 2024.12.16
Microbiota tailored skin humoral immunity and its potential for the development of novel vaccinal approaches
Scientists have just made two major discoveries about a harmless bacterium, Staphylococcus epidermidis, present on our skin. A first study identifies the skin as a compartment able to develop highly protective antibody responses to skin colonizing microbe in the absence of inflammation or lymph node contribution. A second study concerns the development of a topical vaccine that can be applied...
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Fiche maladie | 2023.09.15
Legionellosis
Legionellosis is a collective term for diseases caused by Legionella bacteria, including the potentially fatal Legionnaires' disease. The most common species, Legionella pneumophila, causes a severe lung infection. The recent emergence of the disease can be explained by the affinity of Legionella bacteria for modern water supply systems. Although there is no vaccine for Legionnaires' disease, it...