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Document de presse | 2019.05.09
Nipah outbreaks in Bangladesh: age and breathing difficulties of infected patients increase the risk of disease spread
Nipah virus, a bat-borne paramyxovirus found throughout South and South East Asia, has been identified by WHO as an emerging infectious disease that may cause severe epidemics in the near future. Infections in humans result in severe respiratory and neurological disease with a high case fatality. With no available treatment or vaccine, the control of Nipah virus outbreaks must rely on a detailed...
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News | 2020.02.06
Rabies: new prophylactic and therapeutic avenues
Rabies is still responsible for approximately 60,000 human deaths per year mostly in Asia and Africa and affects especially underserved people. Yet, since the first vaccine developed by Louis Pasteur more than 130 years ago, prophylactic measures have significantly improved. They are now composed of the vaccine allied to purified human or equine rabies immunoglobulins. However, these...
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News | 2020.12.02
Diphtheria: identification of a penicillin resistance gene
Before the vaccine era, diphtheria was the most deadly respiratory infection in young children. There are still outbreaks of diphtheria in some world regions and cases can occur among unvaccinated individuals, with severe consequences. Antibiotics are vital in treating diphtheria, and the emergence of antibiotic resistance is a major public health concern. A team of Institut Pasteur scientists...
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Document de presse | 2021.04.21
SARS-CoV-2: infection induces antibodies capable of killing infected cells regardless of disease severity
Drawing on epidemiological field studies and the FrenchCOVID hospital cohort coordinated by Inserm, teams from the Institut Pasteur, the CNRS and the Vaccine Research Institute (VRI, Inserm/University Paris-Est Créteil) studied the antibodies induced in individuals with asymptomatic or symptomatic SARS-CoV-2 infection. The scientists demonstrated that infection induces polyfunctional antibodies....
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Document de presse | 2022.06.20
How to improve the care of childhood encephalitis in South-East Asia
Encephalitis is an acute inflammation of the brain tissue that affects children and adults, especially in South-East Asia. Researchers and physicians involved in the "South-East Asia encephalitis" (SEAe) project, coordinated by the Institut Pasteur in collaboration with the Pasteur Network, have demonstrated the importance of prevention as well as rapid and appropriate diagnosis and treatment of...
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Portrait | 2024.06.28
Mathieu Picardeau: tackling the trio of water, rats and leptospirosis
Mathieu Picardeau is Head of the Biology of Spirochetes Unit and the National Reference Center for Leptospirosis at the Institut Pasteur. Mathieu is warm, friendly and well-read, with a passion for contemporary art in his free time – but what really gets him excited is a very specific family of bacteria, some of which are fatal for humans. Despite his many responsibilities, he spends time in the...
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News | 2024.09.18
Whooping cough: how do we explain its resurgence in 2024 in France?
In a study coordinated by the Institut Pasteur, scientists describe the dynamics of the whooping cough epidemic in 2024 in France, the worst in 25 years. The scientists also sequenced the genome of almost 70 bacterial isolates collected during the outbreak from January to mid-2024. These analyses allowed them to put forward several theories explaining the current resurgence in circulation of the...
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Fiche maladie | 2015.10.06
Typhoid and paratyphoid fever
Typhoid and paratyphoid fever are infectious diseases that can be fatal if left untreated. They generally occur in regions with low standards of hygiene and particularly affect low- and middle-income countries. In France, 100 to 250 cases are reported every year among travelers or people from endemic areas (Africa, Asia and Latin America).
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Article | 2019.06.20
New diagnostic approaches and innovative therapies
Developing innovative therapeutic approaches to improve treatment of patients and provide a rapid and permanent cure.
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Document de presse | 2025.03.06
How AI will make it easier to anticipate future pandemics
In a Nature perspective paper, scientists across Africa, America, Asia, Australia, and Europe outline for the first time how Artificial Intelligence (AI) can transform the landscape of infectious disease research and improve pandemic preparedness. In the next five years, integrating AI into country response systems could save more lives by anticipating the location and trajectory of disease...