Restriction of SARS-CoV-2 replication by coding and non-coding genes

ROSA project

Aim: Knowledge concerning the interaction of SARS-CoV-2 with human cells is sparse. RNA-sequencing analysis, loss-of-function approaches and mechanistic studies will be used to identify and characterize coding and non-coding genes that restrict viral replication. Taking advantage of some of these naturally occurring viral inhibitors may be an effective strategy in the development of novel drugs to treat the disease.

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