Engineering an ACE2 derived polypeptide for label-free, real-time detection on a smartphone device and therapeutic intervention

isCoVDe – in silico Coronaviruses Decoy project

Aim: The current pandemic of CoV urges for therapeutic options and fast, and cheap diagnosis in alternative to the PCR based technology. We propose characterizing a newly designed polypeptide based on ACE2, which could be the base of detection devices adapted to smartphones and harbors the potential for therapeutic intervention. Focusing on ACE2 overcomes viral mutations, extending the applicability to this and other Coronaviruses.

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