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Article | 2020.07.07
Modeling human SARS-CoV-2 infection in mice with human lung xenografts
To date there is no specific therapeutic treatment or vaccine for COVID-19 caused by the SARS-CoV-2 virus and relevant animal models that mimic human COVID-19 pathologies are lacking. We will generate two novel humanized mouse models: HuLung mice (human lung) and HIS-HuLung mice (and human immune system and human lung). Infection of HuLung and HIS-HuLung mice with SARS-CoV-2 will provide an in...
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Document de presse | 2023.06.06
Monkeypox: characterization of post-infectious immune response
In 2022-2023, an outbreak of monkeypox, now known as mpox (caused by the monkeypox virus or MPXV) led to 87,000 human cases in 170 countries[1]. Most cases were reported outside the usual areas in which the virus circulates. Since the outbreak began, surveillance of the virus has been stepped up in Europe, with nearly 5,000 cases being reported in France[2]. Scientists and clinicians from the...
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Report | 2024.03.12
COVID-19: which monoclonal antibodies should be used for vulnerable individuals?
Vaccination does not offer sufficient protection against severe forms of COVID-19 for people with a weakened immune system. For these individuals, monoclonal antibodies have long been the preferred therapeutic solution. But depending on the SARS-CoV-2 variant, the effectiveness of these treatments has fluctuated. Scientists have had to develop novel antibodies that are more effective while also...
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Article | 2018.01.30
A program concerning the Hand-Foot-And-Mouth disease in South East Asia
The infection called "hand, foot and mouth" (HFMD) is a viral disease that mainly affects children under 5 years. It is transmitted by direct contact between infected children and is characterized by fever, mouth sores and blisters on the hands, feet and buttocks. To date, there is no specific treatment for this disease. A global approach is being developed in Southeast Asia to define...
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Article | 2020.10.05
DEVELOPMENT OF INNOVATION
Development Of InnovationMichel Perez,Head of OfficeThe Development of Innovation Office works with researchers to develop their inventions throughout the acceleration and maturation phases by bringing industrial development skills and helping in attracting specific external funding.This office is composed of scientists with strong background in industrial research and development.The...
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Article | 2024.04.30
Hélène Sparrow: microbe hunter
A Polish-born French physician and biologist, Hélène Sparrow lived through wars and revolution, moving between soldiers’ bedsides and her research laboratory.
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Article | 2016.11.10
The final years 1877-1887
Between the age of 55 and 65 Louis Pasteur developed microbiology, applying it to medicine and surgery. Having established that diseases were caused by microorganisms, he then sought to identify and find a means of fighting them. His finest accomplishment was rabies.
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Document de presse | 2021.05.27
COVID-19, one year on: persistence of protective antibodies and significantly reduced risk of reinfection
A study conducted by the University Hospital of Strasbourg (HUS) in collaboration with the Institut Pasteur, published as a preprint on medRxiv, has led to a significant advance in knowledge about COVID-19.In connection with the SeroCoV-HUS study led by Professor Samira Fafi-Kremer (University Hospital of Strasbourg (HUS) – University of Strasbourg – INSERM UMR1109), the team at Strasbourg...
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News | 2023.10.06
Diphtheria: a novel bacterial species identified
A team from the Institut Pasteur has described a novel bacterial species in the Corynebacteriaceae family, capable of causing diphtheria. The identification of this distinct species will pave the way for improved surveillance and disease prevention.
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News | 2020.07.20
i-Lab 2020 competition: two winners from the Institut Pasteur, one awarded a Grand Prix
On July 16, the i-Lab 2020 innovation competition unveiled the names of 73 winners, which this year included the D4Zin (Grand Prix) and AVATAR MEDICAL projects, both based on research carried out at the Institut Pasteur and supported by the Pasteur Microbes and Health Carnot Institute.Sponsored by the French Ministry of Higher Education, Research and Innovation and organized in partnership with...