Novel approaches to diagnosis, vaccination and therapy (12 entities)

This thematic area gathers investigators with a common interest in translational research. It addresses the design, development and evaluation of candidate vaccines, therapeutics, diagnosis tools, and immunotherapies, for conversion of scientific breakthroughs into improved human health.

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Rogerio Amino - Malaria Infection and Immunity

Malaria parasites; Plasmodium Pre-erythrocytic Stage; Skin and Liver Infection; Multi-antigenic; Vaccine; In vivo Imaging

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David Bikard - Synthetic Biology

CRISPR-Cas loci; Bacterial Genome Editing; Genetic Engineering; Antibiotic Resistance; Bacterial Immune System; DNA Repair

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Roland Brosch - Integrated Mycobacterial Pathogenomics

Mycobacterium Tuberculosis; Pathogenicity; Anti-tuberculosis Vaccine Development; New Anti-tuberculosis Drugs Identification

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Pierre Charneau - Molecular Virology and Vaccinology

Lentiviral-vector-based Vaccines; Prophylactic Anti-Zika Vaccines; Veterinary Anti-Rift Valley Virus Vaccine; Multivalent T-cell -based Vaccine Against Zika, Dengue and Yellow Fever; Anti-tuberculosis Vaccine

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Chetan Chitnis - Malaria Parasite Biology and Vaccines

Malaria Parasites; Blood stage; Red Blood Cells Invasion and Egress; Parasite Ligands; Receptor-ligand Interactions; Multi-component Vaccine Candidates

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James Di Santo - Innate Immunity

Infectious Disease Modeling; Innate lymphoïde Cell Biology; Pathogen Co-infection; Hepatitis C; HIV; Tuberculosis; Malaria

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Pierre Lafaye - Antibody Engineering

Nanobodies; Camel Homodimeric Antibodies (VHH); Phage Display; Blood-Brain-Barrier

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Laurence Mulard - Chemistry of Biomolecules

Carbohydrates; Peptides; Enteric Diseases; Conjugate vaccines; Chemical Probes; Chemistry

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Mery Pina  - Biological Resource Center of Institut Pasteur (CRBIP)

Drug Discovery; biobanking; Research infrastruture; Bioeconomy

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Gerald Spaëth - Molecular Parasitology and Signaling

Leishmania; Cellular Responses to Infection; Drug Discovery

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Frédéric Tangy - Viral Genomics and Vaccination

Live-attenuated Vaccine; Measles virus-based vaccine; Dengue and Zika; Chikungunya HIV, malaria; H5N1, Rabies, SARS-coV 

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Simon Wain-Hobson - Molecular Retrovirology

DNA Mutator enzymes; APOBEC proteins; DNA damage;DNA Double-strand Breaks; Cancer Susceptibility Genes; Cell Stress

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