Replication, Repair and Recombination ( 3R ) and genome stability

Description

This intensive module (one week of lectures, one week of experimental work) is devoted to presenting current concepts and new experimental techniques in the 3 Rs (DNA replication, repair and recombination) and genome stability.

The lectures cover the full range of topics relating to the 3Rs and genomic stability in various living organisms.

The various fundamental molecular mechanisms that ensure the stable transmission of genomic information, as well as their dysregulation, will be examined in detail using different organisms as examples. The consequences of such dysregulation will be analysed, taking into account their societal implications.

The experimental component will take place as part of an immersion programme at the UMR Stabilité Génétique...

The evaluation will be divided between the theoretical and experimental parts.

Theoretical part : Each student will be asked to produce a written summary of the lectures. Students' oral participation will also be taken into account.

Practical training : An oral presentation on the work carried out during the week will be made. The integration in the team and the work carried out by the students will be considered.

Participants (non-exhaustive list) : :

Pr Neil Osheroff, Vanderbilt University, Nashville, USA

Pr Marc Drolet, Université de Montréal, Canada

Dr Ludovic Deriano, Institut Pasteur, Paris, France

Dr ???, Institut Imagine, Université Paris Cité, France

Dr Pascale Lesage, Institut de recherche Saint-Louis, Paris, France

Dr Ludovic Sauguet, Institut Pasteur, Paris, France

Dr Karine Dubrana, CEA, Fontenay-aux Roses, France

Dr Emmanuelle Martini, CEA, Fontenay-aux Roses, France

Dr Eric Coïc, CEA, Fontenay-aux Roses, France

Dr Eric Meyer, CEA, IBENS, Paris, France

PRACTICAL INFORMATION

Location of courses

Courses: Université Paris Cité, Campus des Grands Moulins, Paris 13°

Experimental work: CEA Fontenay-aux roses.

Dates

Lectures: 7-11 October 2026

Experimental work: 14 to 18 December 2026

Language: English

ACCREDITATIONS

Université Paris Cité, Master 2 teaching unit

Application for Qualifying Training in progress.

Université Paris Cité Master 2 students MUST submit their applications to register for the course DIRECTLY to the people in charge of their university course. These students have free access to the course.

All other students -> contact us:

jean-charles.cadoret@ijm.fr ; marc.nadal@u-paris.fr

Web page :

https://eur-gene.u-paris.fr/wp-content/uploads/sites/7/2025/06/Fiche-web-SGE2-MEG-v2.pdf