Video 1 min read

“Hacking” Antibiotic-Resistant Bacteria

Published the Updated By Sacha Tembe and Jeanne Fenouil

What if a single sugar molecule could overcome antibiotic resistance? Didier Mazel, a researcher at the Institut Pasteur, presents a novel strategy to reopen the doors to resistant bacteria and restore the full effectiveness of existing treatments.
  • #Antibiotic resistance
  • #Bacteria
Hacker les bactéries

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© Script: Jeanne Fenouil and Sacha Tembe - Filmmaking: Jeanne Fenouil (video in french, english subtitles available translated by AI)

 

What if we could hack resistant bacteria?

In this video, Didier Mazel, a researcher at the Institut Pasteur, explains how his team is exploring an innovative method to restore the power of antibiotics.

Their idea? Combine a sugar molecule, uridine, with antibiotics from the aminoglycoside family.

The result: even resistant bacteria reopen their doors, and treatments become effective again. It's a simple and promising strategy that offers new hope in the fight against antibiotic resistance.

This video is part of World Antimicrobial Resistance Awareness Week, held from November 18 to 24, 2025.

This is a key moment to highlight the importance of research and innovation in the fight against resistant infections.