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Alzheimer's: what if it all began before memory loss?

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Memory loss is not the first warning sign. At the Institut Pasteur, scientists have identified what goes wrong in the brain long before the first symptoms of Alzheimer's disease appear.
  • #Alzheimer
  • #Pasteurdon
  • #Découverte
Alzheimer : les grandes découvertes

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(video in french, english subtitles available translated by AI)
 

Alzheimer's disease does not begin with memory problems.
Long before they appear, communication between neurons begins to deteriorate.

Scientists at the Institut Pasteur have identified a key player in this phenomenon: a relay that allows neurons to exchange information with one another.

Their research shows that when a protein associated with the disease accumulates in the brain, it disrupts this communication system.

This discovery provides a better understanding of what happens in the very early stages of the disease and opens up new avenues for developing treatments capable of slowing the onset of symptoms.

 

Episode 1/5 of our series “5 Discoveries that advance research.” To ensure that research continues to advance, the Institut Pasteur needs everyone’s support: make a donation at Pasteurdon.fr