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Defense mechanism against HIV-1 revealed

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  • #Recherche fondamentale
  • #Recherche
  • #Recherche

Scientists have discovered how some of these restriction factors inhibit HIV replication in lymphocytes. These proteins belong to the IFITM (interferon-induced transmembrane proteins) family; they are broad-spectrum antiviral proteins that act on a wide range of viruses including influenza, dengue, etc. Little was previously known about their effect on HIV-1.