Segmented filamentous bacteria, partners in intestinal immunity, finally cultured in vitro

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Despite the vital role of segmented filamentous bacteria in establishing gut immune homeostasis in vivo in mice, scientists, for the past 50 years, have been unable to reproduce this symbiosis in vitro to shed light on the cellular and molecular interactions involved. Now, scientists have successfully cultured and reproduced the complex life-cycle of these bacteria outside their host for the first time.

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