Advanced immunology

This five-week intensive laboratory and lecture course presents advanced studies on the main themes in cellular and molecular immunology.

 

The main course comprises :

 

- Three weeks of  state of the art laboratory practical course are meant to introduce students to a research subject investigated by a variety of experimental approaches. It focuses on the characterization of two functions of the AID protein (Activation Induced Cytidine Deaminase) in B cells: isotypic switch and somatic hypermutation.

These roles of AID will be studied in B cells from wild type or AID-KO mice by FACS, ELISA analyses, reporter gene transfection assays, siRNA silencing, sequencing genes undergoing somatic hypermutation and real-time PCR. Some experiments are carried out in the BSL2+ facility of the Institut Pasteur Center for Human Immunology (CIH).

 

- Two weeks of lectures dealing with advanced studies on major topics in cellular and molecular immunology, such as: development of the immune system, lymphocyte differentiation, molecular basis of antigen recognition by B and T lymphocytes, repertoire selection, lymphocyte homeostasis, tolerance, cellular communication, immune responses, innate immunity and various aspects of immunopathology

 

- Three days of thematic bibliography analysis seminars, given early January by groups of students and supervised by two senior scientists. These seminars are mandatory for students enrolled in Master programs and optional for other participants.

 

The program of the course organized the previous year can be downloaded to get detailed information on the general frame of the course; some topics and practical works may change each year, without altering the general aims and means of the course.

 

Program of the course Advanced immunology 2013-2014 (PDF - 400 Ko)

 

Important Information

1) Since Type-2 Biosafety laboratory facilities will be used during the course, students’ updated tetanos and hepatitis B vaccination certificates are required.

 

2) The course requires the students’ personal work during evenings and weekends. Students are asked not to take any engagements in that period of time. For instance, MDs or Pharmacists are asked to get no hospital duties during the period of the course, including during the bibliography seminars week.

 

3) Candidates must have a good knowledge in biochemistry, molecular biology and genetics, as well as a performing first year master level in immunology (or equivalent).

 

4) Students should have good knowledge of English language to be able to understand full lectures, ask questions and deliver the bibliography analysis seminar in English. Understanding of French language is useful, but not mandatory, for daily interactions.

 

5) Students not enrolled in Paris Universities’ Master Programs will have the final exam and finish the course on Saturday after the last lecture. These students may make the thematic bibliography analysis presentations during the workshop type lectures.

 

The committee of the course will evaluate applications.

 

Members of the Teaching Committee :

 

A. Alcover (Institut Pasteur),

P. A. Cazenave (Institut Pasteur/Université P. et M. Curie),

E. Coeffier (Institut Pasteur),

A. Freitas (Institut Pasteur),

C. Fridman* (Université Paris-Descartes),

F. Huetz (Institut Pasteur),

C. Parsot (Institut Pasteur),

A. Six* (Université P. et M. Curie),

M. Viguier* (Université Paris-Diderot),

A. Zider (Université Paris-Diderot).

 

* University Representatives

 

Practical information

 

Title of the course

Advanced immunology

Directors

Andres Alcover

Lymphocyte cell biology unit -Institut Pasteur

 

Antonio Freitas

Lymphocyte population biology unit - Institut Pasteur

Head of studies

François Huetz

Lymphocyte population biology unit - Institut Pasteur

Language

English

Participants

24

Duration

5 +1 weeks

Dates

November 17, 2014 to January 09, 2015

Closing date for application

June 15, 2014

Diplomas

Institut Pasteur Diploma

 

Diplôme d'Université (DU) from University Paris Diderot for people registering at this university (registration fees ≈ 250 €).

 

Credits for a master degree for students registered at Parisian partner universities.

 

Attending conferences can be validated as "module d'école doctorale" for students registered at partner universities.

Contact

enseignement@pasteur.fr

Application

On line registration

 

Registration fees

 

Mis à jour le 21/03/2014

Chiffres clés

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