NMR of Biomolecules

Unit Head : Muriel Delepierre


Our research is mainly dedicated to understanding the function of bio-macromolecules such as proteins, nucleic acids and oligosaccharides through the study of their structure, interactions and dynamics. To this end, we use NMR, biophysical and biochemical techniques and work in collaboration with various groups from the Institut Pasteur and with laboratories in France and abroad.




The main projects currently being undertaken in our laboratory are:

(i) Structural and functional studies of proteins involved in the active transport of nutrients in bacteria;

(ii) The control of neuronal death and survival by the rabies virus glycoprotein;

(iii) PDZ mediated viral perturbation of infected cells signaling pathways;

(iv) Function of whirlin in the mecanoelectric transduction in the internal ear;

(v) Structure and biosynthesis of the fungal cell wall and structural and functional analysis of hydrophobins from the fungal pathogen Aspergillus fumigatus.







NMR of Biomolecules
Muriel Delepierre


Institut Pasteur
28, Rue du Docteur Roux
75724 Paris Cedex 15 FRANCE

Head of the lab : Tel + 33 (0)1 45 68 88 71
Secretary : Tel + 33 (0)1 40 61 37 02
Fax + 33 (0)1 45 68 89 29