Statistical and Mathematical Modeling in Biological Applications

The seminar series Statistical and Mathematical Modeling in Biological Applications (SaMMBA) features monthly lectures and discussions with leading modelers in biological sciences. Presentations are in English or French and target an interdisciplinary audience. Seminars are held on the campus of Institut Pasteur. Access is free. However, to enter the campus, one needs a badge that is obtained at the main gate in exchange of a piece of ID (passport, citizen card or driver licence).

 

For additional information about the series, contact the organizers: Pierre-Yves BöelleRomulus BrebanVittoria ColizzaJudith LegrandLulla OpatowskiVirginie SupervieLaura Temime and Elisabeta Vergu. To arrange to meet with an invited speaker, contact the host of that speaker. 

 

 

Next Lecture

 

Samuel ALIZON

 

Why does HIV harm its host? Clinical and epidemiological applications of virus phylogenies

 

Abstract: Infections by human pathogens such as HIV often vary in their course. For instance, in absence of treatment, some individuals infected by HIV-1 progress to AIDS rapidly, whereas others remain asymptomatic for more than a decade. Most of the research effort has focused on identifying host factors controlling the virulence of HIV infections and it has led to great successes. However, these only explain part of the variance we observe. Recent results show that a fraction of the virulence of the infection could be explained by virus factors. This largely rests on the fact that the set-point viral load seems to be "heritable" from one infection to the next. I will present these results along with three hypotheses that could explain the somehow surprising "heritability" of HIV virulence. If time permits it, I will also present another use of virus phylogenies, namely how they can help us infer epidemiological parameters in the case of the ongoing Ebola virus epidemics in Sierra Leone.

 

Contact: Romulus BREBAN

Tue, Apr 14th, 2015 

  12 noon -1 pm 

Room BIME 28-01-01A

 

 

 

 

 


Full Schedule 2014-2015

 

Yamir MORENO

Dynamics of Interacting Diseases

Abstract 

Tue, Sep 9th, 2014
  12 noon -1 pm 

Chiara POLLETO

Modelling disease spatial spread and real time assessment of emerging pathogen events

Abstract

Wed, Oct 8th, 2014

  12 noon -1 pm 

Room BIME 28-01-01A

Gilles WAINRIB

Integrative network inference of gene expression data and applications to inflammatory bowel disease

Abstract

Tue, Nov 4th, 2014

  12 noon -1 pm 

Room Jean-Paul Aubert

Christian ROBERT

ABC methods for Bayesian model choice

Abstract

Tue, Dec 2nd, 2014

12 noon -1 pm 

Guillaume ACHAZ

The strange case of the Standard Neutral Model of molecular evolution: when, what and why

Abstract

Tue, Jan 13th, 2015 

  12 noon -1 pm

Room DUCLAUX RDC HAUT

Nicolas BACAER

Epidemic models and seasonality

Abstract

Tue, Feb 10th, 2015 

  12 noon -1 pm 

Room BIME 28-01-01A

Benoit PERTHAME

Kinetic models of chemotaxis and traveling pulses

Abstract

Tue, Mar 10th, 2015 

  12 noon -1 pm 

Room DUCLAUX RDC HAUT

Samuel ALIZON

Why does HIV harm its host? Clinical and epidemiological applications of virus phylogenies

Abstract

Tue, Apr 14th, 2015 

  12 noon -1 pm 

Room BIME 28-01-01A

Alan PERELSON

Mathematical modeling and the potential cure of HIV

Abstract

Tue, May 20th, 2015 

  12 noon -1 pm 

Room Retrovirus

Ron BROOKMEYER

Tracking the AIDS Epidemic: Estimating HIV Incidence

Abstract

Tue, June 2nd, 2015 

  12 noon -1 pm 

Room Jean-Paul Aubert

  

 


Full Schedule 2013-2014

 

Alun LLOYD

Modeling novel strategies for controlling mosquito-borne diseases

Abstract 

Tue, Sep 24th, 2013 
  12 noon -1 pm 

Joseph DUREAU

 The Public Library of Models: an open source project towards social modeling

Abstract

Tue, Oct 8th, 2013 
  12 noon -1 pm 

Room Jules Bordet 

Julia GOG

Capturing the spread and evolution of influenza A

Abstract

Tue, Nov 5th, 2013 
  12 noon -1 pm 

Véronique THOMAS-VASLIN

Modélisation de la dynamique lymphocytaire T 

Abstract

Tue, Dec 10th, 2013 
  12 noon -1 pm 

Room Jean-Paul Aubert

Bernard
 CAZELLES

Wavelet analysis as a tool for considering non-stationarity in Epidemiology

Abstract

Tue, Jan 7th, 2014 
  12 noon -1 pm 

Room Jean-Paul Aubert

Jeremie GUEDJ

Modeling hepatitis C viral kinetic in the era of direct acting antiviral agents: review and perspectives

Abstract

Tue, Feb 11th, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert

Peter WHITE

Tackling TB in the Age of Austerity: ensuring we use novel tools and approaches cost-effectively

Abstract

Tue, Mar 4th, 2014
  12:30 noon -1:30 pm

Room Jean-Paul Aubert  

Aurélien LATOUCHE

Regression modeling of the cumulative incidence function with missing causes of failure

Abstract

Tue, Apr 1st, 2014
  12 noon -1 pm

Room Jean-Paul Aubert 

Aaron KING

How to tell if the honeymoon is over: testing hypotheses about pertussis and its resurgence

Abstract

Tue, May 6th, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert 

Carlo Giovanni CAMARDA

Modelling Social Contact Data: a smoothing constrained approach

Abstract

Tue, Jun 10th, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert 
Updated on 12/03/2015

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