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  • The three-dimensional structure of SUB1, Highly regulated therapeutic target shows promise in the search for new antimalarial treatments, © Jean-Christophe Barale, Institut Pasteur

    Press release | 10.09.2014

    Highly regulated therapeutic target shows promise in the search for new antimalarial treatments

    Artemisinin is currently the most effective malarial treatment available. However, the recent emergence in South-East Asia of artemisinin-resistant parasites strengthens the urgent need to identify a new generation of antimalarial drugs. In this context, scientists have determined the three-dimensional structure of a promising new therapeutic target for malaria: SUB1.

  • A neuron seen under fluorescence microscopy, Autism: SHANK gene may indicate the severity of the disorder, © Institut Pasteur

    Press release | 04.09.2014

    Autism: SHANK gene may indicate the severity of the disorder

    Thanks to a large-scale study conducted on nearly 1,000 autistic patients, scientists succeeded in mapping the clinical incidence and impact of certain genetic mutations linked to the cognitive and intellectual abilities of the patients. Mutations affecting the SHANK3 gene were shown to coincide with the most severe cases of autism and are associated with 1 out of 50 children with autism and intellectual deficits.

  • Neo-neurons in an adult brain, Pierre-Marie Lledo, Mental states control the integration of new neurons in the adult brain, © Institut Pasteur

    Press release | 02.09.2014

    Mental states control the integration of new neurons in the adult brain

    Although it has been known for several years that the adult brain is capable of producing new neurons, how these neurons are integrated into existing, functional nerve circuits has hitherto remained a mystery. Scientists have just shown that new neurons set up a denser network of connections with the rest of the brain in contexts of active (as opposed to passive) motivation and learning.

  • Ebola virus, The Institut Pasteur steps up its action against Ebola, © Institut Pasteur

    Press release | 01.09.2014

    The Institut Pasteur steps up its action against Ebola

    Ever since the Ebola virus was identified in Guinea in March 2014, the designated WHO Collaborating Centers within the Institut Pasteur and Institut Pasteur International Network have been assisting the international aid initiative via diagnostic support and epidemiological surveillance. Now, faced with the seriousness and spread of the epidemic, the Institut Pasteur and Institut Pasteur International Network are strengthening and coordinating their efforts in order to effectively fight the disease.

  • Potential strategies for limiting the hepatitis C epidemic in Egypt

    Press release | 28.08.2014

    Potential strategies for limiting the hepatitis C epidemic in Egypt

    In the fight against hepatitis C, directing preventive and curative interventions towards sufferers of chronic diseases requiring regular medical care would be an effective means of reducing transmission of the hepatitis C virus (HCV) in Egypt, and undoubtedly also in other countries with limited resources. This theory has arisen from a mathematical modeling study carried out as part of the ANRS 1211 study, conducted jointly by scientists at the Institut Pasteur, the CNAM and their fellow scientists in Egypt.

  • A new mechanism of gene regulation in Listeria, Listeria invading an epithelial cell, © Institut Pasteur

    Research | 22.08.2014

    A new mechanism of gene regulation in Listeria

    How do bacteria perceive their environment? How do they find and detect nutrients? How do they eat? In an article published in the journal Science, researchers reveal a new system of gene regulation in Listeria monocytogenes, the bacteria in food and responsible for listeriosis.

  •  Americas Regional Meeting of the Institut Pasteur International Network

    International News | 14.08.2014

    Americas Regional Meeting of the Institut Pasteur International Network

    The Americas Meeting of the Institut Pasteur International Network which includes the Institut Pasteur in Guadeloupe, Guyana, Montevideo, the Institut Armand-Frappier and the Fiocruz, has been organized by the Centre INRS - Institut Armand-Frappier in Laval on the 1st of August, 2014 as part of the International Union of Microbiological Societies' Conference that took place in Montreal from July 30th to August 1st, 2014.
     
    125 people from the Institut Pasteur International Network and the Institut Pasteur in Paris have met in Montreal during the conference. Discussions with researchers from the five institutes in the region were the opportunity to take stock of public health issues specific to this geographical area: chikungunya, dengue fever, tuberculosis, leishmaniasis and leptospirosis. The preparation of research programs and training in connection with other Institutes from the Network were discussed. The researchers also confirmed the definite significance of the establishment of a regional platform in Bioinformatics.

  • Streptococcus agalactiae in white blood cells (polynuclear neutrophils) in the cerebrospinal fluid of a child with meningitis (optical microscopy, Gram stain). © Claire Poyart, CNR-Strep (AP-HP, Inserm)

    Press release | 04.08.2014

    The emergence of neonatal group B streptococcal infections explained

    Scientists from the Institut Pasteur and the CNRS have recently revealed the cause behind the emergence in the 1960s of neonatal infections due to group B streptococcus. These findings prove that the sudden emergence of infections caused by this bacterium resulted from the widespread use of an antibiotic, tetracycline, from the 1950s onwards.

  • International News | 30.07.2014

    Institut Pasteur and Institut Pasteur of Dakar on the front line against the Ebola crisis in West Africa

    Since the beginning of the Ebola outbreak in Guinea, several scientists from the Institut Pasteur, as part of their mandate as a WHO Collaborating Centre on arboviruses and viral hemorrhagic fevers, have been offering their support to international aid plan implemented in collaboration with the Guinean Ministry of Health.

  • Section of Mycobacterium bovis © Institut Pasteur/Antoinette Ryter

    Research | 22.07.2014

    TB transmission: Why tubercle bacilli of animal origin don't spread within human populations

    Researchers examined the mechanisms involved in tuberculosis (TB) transmission to explain why tubercle bacilli of animal origin don't spread within human populations. Their work opens up new possibilities for understanding the functions and mechanisms involved in TB transmission in humans and could eventually lead to therapeutic solutions for preventing the spread of this infectious agent.

     

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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France
 

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