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  • Photomontage showing the mold Aspergillus fumigatus growing alone (left panel) and stimulated by the presence of the bacterium Pseudomonas aeruginosa (right panel). Airborne Bacterial Volatiles stimulate Fungal Growth. © Institut Pasteur

    Research | 06.04.2016

    Airborne Bacterial Volatiles stimulate Fungal Growth

    Scientists from the team led by Jean-Paul Latgé, Director of the Aspergillus Unit at the Institut Pasteur, have discovered a new communication pathway between two pathogens that colonize the same ecological niche and are both involved in acute pulmonary pathologies, particularly in patients with cystic fibrosis (the most common genetic disease in Europe).

  • Spheroid of renal cells cultivated in vitro. Division – a key moment in establishing cell polarity. Institut Pasteur

    Research | 04.04.2016

    Division – a key moment in establishing cell polarity

    One major line of research on the process of carcinogenesis lies in understanding the mechanisms underpinning the establishment of polarity. The Membrane Traffic and Cell Division Laboratory, directed at the Institut Pasteur by Arnaud Echard (Institut Pasteur/CNRS UMR 3691), is looking into apical-basal polarity acquisition mechanisms during cell division when organs are being formed. As part of this research, the team has recently discovered the crucial role of a GTPase-type enzyme known as Rab35.

  • Human cells infected with Chlamydia trachomatis. How Chlamydia trachomatis hijacks energy stores from its host. Institut Pasteur

    Research | 25.03.2016

    How Chlamydia trachomatis hijacks energy stores from its host

    A publication in eLife from researchers of the Institut Pasteur, CNRS, University of Lille and Indiana University (USA) explains the mechanisms by which the bacterium Chlamydia trachomatis hijacks nutrients of its host to its own benefit.

  • Lluis Quintana-Murci, Scientific Director of the Institut Pasteur. © Giovanni Cittadini Cesi

    Press release | 23.03.2016

    Lluis Quintana-Murci appointed as Scientific Director of the Institut Pasteur

    On March 23, the Institut Pasteur announced that Lluis Quintana-Murci had been appointed as Scientific Director. This new position has been created in connection with the implementation of the general strategic plan adopted by the Institut Pasteur management. Lluis Quintana-Murci, a member of the Executive Board, will serve as the person of reference and coordinator for the Institut Pasteur's scientific teams. The aim is to facilitate the formalization and day-to-day implementation of the Institut Pasteur's scientific policies and to coordinate scientific evaluation activities and related action plans.

  • Colored image of Shigella, the agent of bacillary dysentery. A genomic study of epidemic dysentery: how Europe exported a scourge worldwide. © Institut Pasteur

    Press release | 21.03.2016

    A genomic study of epidemic dysentery: how Europe exported a scourge worldwide

    Scientists at the Institut Pasteur and its International Network, the Wellcome Trust Sanger Institute (Cambridge, United Kingdom) and several international institutions have just published an exceptionally wide-ranging study tracing the history of the bacillus responsible for epidemic dysentery – one of the worst scourges to afflict humans throughout the 18th and 19th centuries. This vast scientific investigation has uncovered hitherto unknown links between the various outbreaks that have occurred through history.

  • Zika and microcephaly: first trimester of pregnancy most critical. Institut Pasteur

    Press release | 16.03.2016

    Zika and microcephaly: first trimester of pregnancy most critical

    A new analysis of data from the 2013-2014 Zika epidemic in French Polynesia by scientists from the Institut Pasteur, Paris, and their French Polynesian colleagues has confirmed the incidence of grouped cases of microcephaly and quantified the risk of microcephaly associated with the virus. Using innovative mathematical modeling techniques, their research shows that the risk of microcephaly is around 1% for a fetus or newborn whose mother has been infected by the Zika virus during the first trimester of pregnancy.

  • Vibrio cholerae. Unmasking an ancestral mechanism of integrons — key players in antibiotic resistance. © Institut Pasteur

    Research | 10.03.2016

    Unmasking an ancestral mechanism of integrons — key players in antibiotic resistance

    With the ultimate aim of combating antibiotic resistance acquired by bacteria during evolution, researchers from the Institut Pasteur and CNRS have managed to shed light on one of the mechanisms of DNA recombination in bacteria.

  • DNA sequencing. © Institut Pasteur

    Press release | 07.03.2016

    Obesity: an epigenetic track to fight against weight gain and hypercholesterolemia

    The number of obesity cases has doubled since 1980: in 2014, over 600 million adults were affected across the world. The causes of this epidemic include unbalanced diet, as well as environmental and genetic factors. French researchers reveal that an epigenetic factor, the BAHD1 protein, participates in the regulatory mechanisms of cholesterol levels and weight gain. These results open new ways for finding therapies against obesity, diabetes and cardiovascular diseases.

  • Launch of the AFRIBIOTA research program: a new approach in the fight against child malnutrition. © Thomas Kesteman - Institut Pasteur Madagascar

    Press release | 07.03.2016

    Launch of the AFRIBIOTA research program: a new approach in the fight against child malnutrition

    More than 30 Madagascan and international scientists and clinicians met from March 7 to 9, 2016 at the Institut Pasteur in Madagascar for the official launch of the AFRIBIOTA project, an ambitious multidisciplinary research program to improve our understanding of chronic child malnutrition. The long-term aim of this innovative program, which combines fundamental and clinical research – especially research into the intestinal microbiota in children in conjunction with social science and neuroscience research – is to develop new diagnostic approaches that can be easily used in the field.

  •  On the left: Aedes aegypti mousquito, on the right: Aedes albopictus mousquito. © Institut Pasteur

    Press release | 04.03.2016

    Low competence of Aedes mosquitoes for Zika virus transmission

    The Institut Pasteur's Arboviruses and Insect Vectors Unit, led by Anna-Bella Failloux, has carried out a study on the vector competence of seven populations of Aedes aegypti and Aedes albopictus collected in Guadeloupe, French Guiana, Martinique, Brazil and the United States. The results, published in PLoS Neglected Tropical Diseases, show that, while Aedes aegypti and Aedes albopictus are both capable of becoming infected and replicating the virus in their body, they are not very competent when it comes to transmitting the Zika virus through a bite.

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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France
 

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