One major line of research on the process of carcinogenesis lies in understanding the mechanisms underpinning the establishment of polarity. The Membrane Traffic and Cell Division Laboratory, directed at the Institut Pasteur by Arnaud Echard (Institut Pasteur/CNRS UMR 3691), is looking into apical-basal polarity acquisition mechanisms during cell division when organs are being formed. As part of this research, the team has recently discovered the crucial role of a GTPase-type enzyme known as Rab35.
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