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  • Illustration © Jérome Bon

    Press release | 21.10.2016

    Africans and Europeans have genetically different immune systems... and Neanderthals had something to do with it

    In a large-scale study, scientists from the Institut Pasteur and the CNRS unraveled the immune responses of 200 African and European individuals. They show that there is indeed a difference in the way these populations respond to infection, that this response is largely controlled by genetics, and that natural selection has played an important role in shaping such immune profiles.

  • Press release | 12.10.2016

    Press release following publication of an article in The Korea Times on October 5, 2016

    In an article published online in The Korea Times on October 5, 2016, serious accusations were made against the Institut Pasteur in Korea and the Institut Pasteur in Paris and its President.

  • Trypanosomes (Trypanosoma brucei brucei, fluorescent green) in the dermis of a mouse with no parasites in the bloodstream, 29 days after infection. Sleeping sickness: parasites found hiding in the skin. © Institut Pasteur

    Press release | 22.09.2016

    Sleeping sickness: parasites found hiding in the skin

    Scientists have demonstrated the presence of a large quantity of trypanosomes – the parasites responsible for sleeping sickness – in the skin of individuals with no symptoms. This discovery should refocus the screening strategy for this disease, which was previously based on the detection of parasites in the bloodstream, and raises the possibility of eliminating the disease in West Africa.

  • Localization of bacteria in the ileum of mice given a normal diet (left-hand image) and a high-fat diet (right-hand image). Too much fat rapidly disrupts the balance of the gut microbiota. © Institut Pasteur

    Press release | 19.09.2016

    Too much fat rapidly disrupts the balance of the gut microbiota

    A destabilizing factor such as a change in diet can disrupt the entire gut microbiota, with possible health consequences. An international study has recently demonstrated in mice that a high-fat diet has a direct influence on the gut microbiota and its environment. Bacterial communities react to this new diet with a massive reorganization, and the small intestine itself undergoes changes in its defense capacity – from the very first month.

  • Representation of space in the nicotinic receptor. Alzheimer's: nicotinic receptors as a new therapeutic target.  © Institut Pasteur

    Press release | 29.08.2016

    Alzheimer's: nicotinic receptors as a new therapeutic target

    Several scientific studies have indicated that nicotine may be beneficial for memory function. Scientists from the Institut Pasteur and the CNRS set out to shed further light on the properties attributed to nicotine – which is known to have an adverse effect on health – by determining the precise structure of the nicotinic receptors in the hippocampus region of the brain. Using mouse models for Alzheimer's disease, they identified the β2 subunit of the nicotinic receptor as a target that, if blocked, prevents the memory loss associated with Alzheimer's.

  • The Mycobacterium tuberculosis bacterium, causative agent of tuberculosis. Tuberculosis: a promising vaccine candidate. © Institut Pasteur

    Press release | 02.08.2016

    Tuberculosis: a promising vaccine candidate

    Scientists have published the results of their research into the action mechanisms of a promising experimental tuberculosis (TB) vaccine. BCG, the only currently approved TB vaccine, has been around for almost a century, but it is only partially effective and the protection it offers fades over time. Given the current emergence of adult TB cases in conjunction with the HIV epidemic and the rise in multidrug-resistant TB strains, the development of a new, more effective vaccine is a global health priority.

  • Anopheles stephensi infected by Plasmodium berghei

    Press release | 18.07.2016

    Malaria: a genetically attenuated parasite induces an effective, long-lasting immune response

    With nearly 3.2 billion people currently at risk of contracting malaria, scientists from the Institut Pasteur, the CNRS and Inserm have experimentally developed a live, genetically attenuated vaccine for Plasmodium, the parasite responsible for the disease. By identifying and deleting one of the parasite's genes, the scientists enabled it to induce an effective, long-lasting immune response in a mouse model. These findings were published in the Journal of Experimental Medicine on July 18, 2016.

  • Bacteriophages on the Escherichia coli bacterium. Phage therapy: fundamental action mechanisms revealed. © Institut Pasteur

    Press release | 07.07.2016

    Phage therapy: fundamental action mechanisms revealed

    Scientists identify for the first time the genetic and metabolic mechanisms underpinning the therapeutic action of a bacteriophage known for its therapeutic potential. Given the worrying rise in bacterial resistance to antibiotics and the difficulties in developing effective new molecules, there has been renewed interest within the scientific community in recent years in phage therapy, which makes use of these bacterial viruses.

  • A new adult-born neuron. The relentless dynamism of the adult brain. © Institut Pasteur/PM Lledo

    Press release | 30.06.2016

    The relentless dynamism of the adult brain

    Scientists were able to make real-time observations over a period of several months that reveal how new adult-born neurons are formed and evolve in the olfactory bulb of mice. They made the surprising discovery that there is constant structural plasticity in the connections established by these new neurons with the circuits into which they are recruited.

  • Anopheles gambiae mousquito. © Institut Pasteur/Paul Brey

    Press release | 23.06.2016

    Malaria - First global mapping of artemisinin resistance confirms definitively that resistance is confined to Southeast Asia and has not spread to sub-Saharan Africa

    The first global mapping of artemisinin resistance (the KARMA study) has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub–Saharan Africa.



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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France

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