Genome analysis

Mechanisms of Living Organisms

This seven-week intensive laboratory and lecture course presents all concepts, technics and tools necessary for studying genomes, from experimental setups to data analysis. The different facets of genomics and its applications will be presented, and illustrated by examples from the most recently published research developments and results.

Practical information

Institut Pasteur
November 4-December 20, 2019
June 22, 2019
In French


Credits for a Master 2 degree Université de Paris
Credits for a Master 2 degree Sorbonne Université
Credits for a Master 2 degree Paris Sud
Doctoral School Module
Institut Pasteur Diploma
University diploma Paris Diderot

The Genomes Analysis course associate two complementary sides of genomes studies: a “wet-lab” experimental approach and the analysis of its results through bioinformatics tools.

The lectures given by expert scientists present cutting edge genomic and post-genomic technologies, as well as provide state of the art knowledge in domains such as genome structure and expression, evolution, epigenomics, gene expression regulatory networks, in both model and pathogenic organisms, metagenomics and natural or artificial population analysis.

The genomic and bioinformatics practical trainings allow applying the different concepts presented in the lectures.  The wet-lab part will be divided in two projects. The first will focus on the metagenomics analysis of microbial communities using HiC technologies. The second will be dedicated to the study of a set of non-coding RNAs (piRNA) and of their regulatory role on the Drosophila melanogaster transposable elements.

A good knowledge of genetics, molecular biology and biochemistry is mandatory; i.e. end of master 1 level. In terms of bioinformatics there is no prerequisite. Bioinformatics methodologies and training will be taught along the course process. Computer access will be provided for all students in order to practice and apply the learned methodologies on their data sets. Applications will be evaluated by the Genome Analysis course committee.


More informations


Didier Mazel

Unité Plasticité du Génome Bactérien

Institut Pasteur


Stéphane Le Crom

Institut de Biologie Paris-Seine

UPMC - Sorbonne Université

Head(s) of laboratory practicals

Lionel Frangeul

Unité Virus et interférence ARN

Institut Pasteur

7 weeks
Members of the Course committee

M. Badoual* (Université Paris-Saclay),

S. Bloyer* (Université Paris-Saclay),

L. Frangeul (Institut Pasteur),

J. Heuvingh (ESPCI),

S. Le Crom* (Sorbonne Université),

D. Mazel (Institut Pasteur),

V. Ponticelli (Institut Pasteur),

M. Sala (Institut Pasteur),

R.A. Veitia* (Université de Paris),

H. Waxin (Institut Pasteur).

* Représentants des Universités

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