LANGUAGE: ENGLISH, SUBTITLED FRENCH AND ENGLISH
In 2016, the "review on antimicrobial resistance", chaired by Jim O'Neill, estimated that without action, in 2050, 10 million people a year could die from drug-resistant infections. While this figure is hypothetical, the current situation led WHO to classify the emergence and spread of antibacterial agents as an "increasingly serious threat to global public health that requires action across all government sectors and society."
The MOOC "Resistance to antibacterial agents" addresses the major public health problem of the emergence of multidrug-resistant bacteria isolates, which are responsible for an increase in the morbidity and mortality of a wide range of infections caused by bacteria.
In this course, we provide basic knowledge regarding resistance to antibacterial agents and address key questions in the field. This MOOC first presents different antibacterial agents and their use for animals and humans. It describes the current epidemiological landscape of antibiotic resistance across the globe and explain how the resistance is detected in the medical laboratories. The MOOC then presents the origins of antibiotic resistance and its mechanisms of dissemination, before proposing different approaches to control its spread. Finally, this MOOC highlights the alternatives to antibiotics, the most current molecules in use, and ongoing novel molecule development.
This MOOC is aimed at undergraduate, graduate and PhD biology students, medical doctors, teachers, researchers and all those who want to learn how antibacterial agents work and how resistant strains have emerged and disseminated. A good scientific background is recommended to follow this MOOC.
This MOOC is organized in 6 weeks. Each week is composed of 3 to 6 lectures. Each lecture includes a 10 minute video and 2 multiple choice questions to help participants test their understanding. The videos are in English, subtitled in French and in English. All the tests are in English. This MOOC also proposes a weekly evaluation, using about 10 multiple choice questions (MCQs) and, at the end of the course, a final evaluation, with 30 MCQs.