1995

LIII-HOFNUNG, M. 1995. An intelligent channel (and more). Science, 267, 473-474.

145-NEWTON, S.M.C., KLEBBA, P.E., HOFNUNG, M. & CHARBIT, A. 1995. Studies of
the anaerobically induced promoter pnirB and the improved expression of bacterial antigens. Res.
Microbiol., 146 n¡3, 193-202.

146-SHARFF, A.J., RODSETH, L.E., SZMELCMAN, S., HOFNUNG, M. & QUIOCHO,
F.A. 1995. Refined structures of two insertion/deletion mutants probes function of the
maltodextrin binding protein. J. Mol. Biol., 246, 8-13.

LIV-LECLERC, C., LO-MAN, R., FAYOLLE, C., CHARBIT, A., CLEMENT, J.M.,
MARTINEAU, P., O'CALLAGHAN, D. & HOFNUNG, M. 1995. Immunogenicity of foreign
B- or T-cell epitopes expressed by bacterial hybrid proteins. pp. 217-226. In : "Genes for
development, cell growth and infectious diseases. A decade of Pasteur Riken collaboration. G.
Gachelin, Y. Ikawa, S. Ishii, P. Kourilsky & M. Yaniv (Ed.) John Libbey Eurotext, Paris.


LV-CLEMENT, J.-M., LECLERC, C., LO-MAN, MARTINEAU, P., CHARBIT, A.,
SZMELCMAN, S. & HOFNUNG, M. 1995. Recombinant DNA vaccines : use of Escherichia
coli envelope proteins as tools for cellular and molecular targeting of foreign polypeptides in
bacteria and protein purification. In : Trends and future perspectives in peptide and protein
drug delivery. Lee V.H.L., Hashida M., Mizushima Y. (Eds) Harwood Academic Publishers gmbh.
Proceedings of the international symposium ÒDelivery of protein drugs - the next 10 yearsÓ.
September 2-4, 1993 Kyoto (Japan), 253-271.

147-KUAN, G., DASSA, E., SAURIN, W., HOFNUNG, M. & SAIER, M.H. 1995.
Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-
dependent ABC-type nutrient uptake permeases. Res. Microbiol., 146 n¡ 4, 271-278.

LVI-LECLERC, C., LO-MAN, R., FAYOLLE, C., CHARBIT, A., MARTINEAU, P.,
CLEMENT,  J.-M. & HOFNUNG, M. 1995. Propriétés immunologiques d'pitopes trangers
insérés génétiquement dans des sites permissifs de protéines. Colloques Internationaux de l'Année
Pasteur "Les vaccins, un sicle aprs Louis Pasteur" (24-28 Septembre 1995, Paris, France).
p.Ê83-86.

 

1996        

148-TOUATI E., LAURENT-WINTER C., QUILLARDET P. & HOFNUNG M. 1996. Global
response of Escherichia coli cells to a treatment with 7-methoxy-2-nitronaphtho[2,1-b] furan
(R7000), an extremely potent mutagen. Mutation Research, 349, 193-200.

149-BACHELLIER S. & HOFNUNG M. 1996. The members of the so called BEE95 family of
dispersed enterobacterial intergenic elements are already known under the name RSA sequences.
Mol. Microbiol., 19, n¡6, 1385.

150-STAROPOLI I., CLEMENT J.-M., FRENKIEL M.P., HOFNUNG M. & DEUBEL V.
1996. Dengue virus envelope glycoprotein can be secreted from insect cells as a fusion with the
maltose-binding protein. Journal of Virological Methods, 56, 179-189.

151-BETTON J.-M. & HOFNUNG M. 1996. Folding of a mutant maltose binding protein of
E.coli which forms inclusion bodies. Journal of Biological Chemistry, 271, 8046-8052.

152-NEWTON S. M. C., KLEBBA P. E., MICHEL V., HOFNUNG M. & CHARBIT A. 1996.
Topology of the membrane protein LamB by epitope tagging and a comparison with the Xray
model. J. Bacteriol., 178, n¡12, 3447-3456.

153-BETTON J.-M., BOSCUS D., MISSIAKAS D., RAINA S. & HOFNUNG M. 1996.
Probing the structural role of an ab loop of maltose-binding protein by mutagenesis : Heat-shock
induction by loop variants of the maltose-binding protein that form periplasmic inclusion bodies. J. Mol. Biol., 262 n¡2, 140-150.

154-LO-MAN R., MARTINEAU P., MANOURY-SCHWARTZ B., HOFNUNG M. &
LECLERC C. 1996. Overcoming the crypticity of a viral T cell determinant by insertion into a
chimeric bacterial protein. International Immunology, 8 n¡8, 1245-1255.

LVII-BACHELLIER S., GILSON E., HOFNUNG M. & HILL C.W. 1996. Repeated
sequences. In Escherichia coli and Salmonella : Cellular and Molecular Biology". 2nd ed. R.
Curtiss, III, C.A. Gross, J.L. Ingraham, E.C.C. Lin, K. Brook Low, Jr, B. Magasanik, W.
Reznikoff, M. Riley, M. Schaechter, H. E. Umbarger (Eds). F. C. Neidhardt, American Society
of Microbiology, Washington. Vol. 2, pp. 2012-2040.

155-LO-MAN R., MARTINEAU P., HOFNUNG M. & LECLERC C. 1996. Homogeneous
processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC
genetic background. Cellular Immunology, 172, 180-191.

156-CLMENT J.-M., JEHANNO M., POPESCU O., SAURIN W. & HOFNUNG M.
1996. Expression and biological activity of genetic fusions between MalE, the maltose binding
protein from E. coli and portions of CD4, the T-cell receptor of the AIDS virus.
Protein Expression and Purification, 8, 319-331.

157-LO-MAN R., MARTINEAU P., DRIAUD E., NEWTON S. M., JEHANNO M.,
CLMENT J.-M.,  FAYOLLE C., HOFNUNG M. & LECLERC C. 1996. Control by H-2 genes
of the Th1 response induced against a foreign antigen expressed by attenuated S.
typhimurium.Infection and Immunity, 64 n¡11, 4424-4432.

158-TOUATI E., KRIN E., QUILLARDET P. & HOFNUNG M. 1996. 7-methoxy-2-
nitronaphtho[2,1-b]furan (R7000)-induced mutation spectrum in the lacI gene of E. coli : influence
of SOS mutagenesis. Carcinogenesis, 17 n¡12, 2543-2550.

159-QUILLARDET P., TOUATI E. & HOFNUNG M. 1996. Influence of the uvr-dependent
nucleotide excision repair on DNA adducts formation and mutagenic spectrum of a potent
genotoxic agent : 7-methoxy-2-nitronaphtho[2,1-b]furan (R7000).
Mutation Research, 358 n¡1, 113-122.

160-MARTINEAU P., LECLERC C. & HOFNUNG M. 1996. Modulating the immunological
properties of a linear B-cell epitope by insertion into permissive sites of the MalE protein.
Molecular Immunology, 33 n¡17-18, 1345-1358.

 

1997

LVIII-CHARBIT A., NEWTON S. M., KLEBBA P.E., CLMENT J.-M.,  FAYOLLE C., LO-
MAN R., LECLERC C. & HOFNUNG M. 1997. Expression and immune response to foreign
epitopes in bacteria. Perspectives for live vaccine development. 2nd International Meeting on New
approaches to bacterial vaccine development. 28-30 May 1996, Munich, Germany. Behring
Institute Mitteilungen. 98, 135-142.

161-LECROISEY A., MARTINEAU P., HOFNUNG M. & DELEPIERRE M. 1997. NMR
Studies on the flexibility of the poliovirus C3 linear epitope inserted into different sites of the
maltose-binding protein. J. Biol. Chem., 272 n¡ 1, 362-368.

162-SZMELCMAN S., SASSOON N., HOFNUNG M. 1997. Residues in the a helix 7 of the
bacterial maltose binding protein which are important in interactions with the Mal FGK2 complex.
Protein Science, 6, 628-636.

163-MEYER J.E.W., HOFNUNG M. & SCHULZ G.E. 1997. Structure of maltoporin from
Salmonella typhimurium  ligated with a nitrophenyl-maltotrioside. J. Mol. Biol., 266, 761-775.

164-LECLERC C., MARTINEAU P., CHARLOT B., DELPEYROUX F., VAN DER WERF S.
& HOFNUNG M. 1997. Control by Ig genes of the responsiveness to a neutralization viral B cell
epitope. J. Immunol., 158, 3252-3258.

165-VULLIEZ-LE NORMAND B., SAUL F. A., MARTINEAU P., LEMA F., HOFNUNG M.
& BENTLEY G. A. 1997. Maltodextrin-binding protein hybrids carrying epitopes from the preS2
region of the hepatitis B virus : expression, antibody-binding and preliminary crystallographic
studies. Protein Engineering, 10 n¡2, 175-180.

166-MOUREZ M., HOFNUNG M. & DASSA E. 1997. Subunits interactions in ABC
transporters. A conserved sequence in hydrophobic membrane proteins of periplasmic permeases
defines an important sites of interaction with the ATPase subunits. The EMBO J., 16 n¡11, 3066-
3077.

167-BACHELLIER S., CLMENT J.-M., HOFNUNG M. & GILSON E. 1997. Bacterial
Interspersed Mosaic Elements (BIMEs) are a major source of sequence polymorphism in E. coli
intergenic regions including specific associations with a new insertion sequence. Genetics, 145,
551-562.

168-KLEBBA P.E., NEWTON S.M.C., CHARBIT A., MICHEL V., PERRIN D. &
HOFNUNG M. 1997. Further genetic analysis of the C-terminal external loop region in
Escherichia coli maltoporin. Res. Microbiol., 148 n¡5, 375-387.

169-BETTON J.-M., JACOB J.P., HOFNUNG M. & BROOME-SMITH J.K. 1997. Creating a
bifunctional protein by insertion of §-lactamase into the maltodextrin-binding protein.
Nature/Biotechnology, 15, 1276-1279.

170-WANG J., BETTON J.-M., MICHEL V., HOFNUNG M., CHARBIT A. 1997.
Identification of a cryptic porin gene in the Escherichia coli genome. Expression and insertion of a
monomeric form of the protein into the outer membrane. Molecular Microbiology, 26, 1141-1143.

 

1998

171-BETTON J.-M., SASSOON N., HOFNUNG M., LAURENT M. 1998. Degradation versus
aggregation of misfolded maltose-binding protein in the periplasm of Escherichia coli. J. Biol.
Chem., 273, n¡ 15, 8897-8902.

172-LO-MAN R., LANGEVELD J. P. M., MARTINEAU P., HOFNUNG M., MELOEN R. H.
& LECLERC C. 1998. Immunodominance does not result from peptide competition for MHC
class II presentation. J. Immunol., 160, 1759-1766.

173-WANG J., MICHEL V., HOFNUNG M. & CHARBIT A. 1998. Cloning of the J gene of
bacteriophage Lambda, expression and solubilization of the J protein : first in vitro studies on the
interactions between J and LamB, its cell surface receptor. Res. Mic., 149 n¡ 9, 611-624.

174-RAFFY S., SASSOON N., HOFNUNG M. and BETTON J. M. 1998. Tertiary structure-
dependance of misfolding substitutions in loops of the maltose-binding protein. Protein Science,
7, n¡ 10, 2136-2142.

175-QUILLARDET P., BOSCUS D., TOUATI E. and HOFNUNG M. 1998. DNA damage
induced in vivo by 7-methoxy-2-nitronaphtho[2,1-b]- furan (R7000) in the lacI gene of
Escherichia coli Mutation Research, 422 n¡2, 237-245.

176-CHARBIT A., WANG J., MICHEL V. and HOFNUNG M. 1998 A cluster of charged and
aromatic residues in the C-terminal portion of maltoporin participates in sugar binding and uptake.
Molecular & General Genetics, 260, 185-192.

 

1999 

177-WANG J., MICHEL V., LECLERC C., HOFNUNG M. & CHARBIT A. 1999.
Immunogenicity of viral B-cell epitopes inserted into two surface loops of the Escherichia coli K12
LamB protein and expressed in an attenuated aroA strain of Salmonella typhimurium.
Vaccine, 17, 1-12.

178-SAURIN W., HOFNUNG M. & DASSA E. 1999. Getting in or out. Early segregation
between importers and exporters in the evolution of ATP-Binding cassette (ABC) transporters.
Journal of Molecular Evolution, 48 n¡1, 22-41.

179-TAPIA, M.I., MOUREZ, M., HOFNUNG, M. & DASSA, E. 1999. Structure-function
study of MalF protein by random mutagenesis. J. Bacteriol., 181 n¡7, 2267-2272.

180-ANDERSEN C., BACHMEYER C., TAUBER H., BENZ R., WANG J., MICHEL V.,
NEWTON S.M.C., HOFNUNG M. & CHARBIT A. 1999. In vivo and in vitro studies of major
surface loop deletion mutants of the Escherichia coli K12 maltoporinÊ: contribution to maltose and
maltooligosaccharide transport and binding. Mol. Microbiol., 32 n¡4, 851-867.

181-DASSA E., HOFNUNG M., PAULSEN I.P., SAIER Jr M.H. 1999. The Escherichia coli
ABC transporters : an update (letter). Mol. Microbiol. 32 n¡4, 887-889.

182-CLEMENT J.-M., WILDE C., BACHELLIER S., LAMBERT P. & HOFNUNG M. 1999
IS1397 is active for transposition into the chromosome of Escherichia coli K-12 and inserts
specifically into palindromic units of bacterial interspersed mosaic elements.
Journal of Bacteriology, 181 n¡22, 6929-6936.

183-BACHELLIER S., CLEMENT J.-M. & HOFNUNG M. 1999. Short palindromic repetitive
DNA elements in enterobacteria : a survey. Research in Microbiology, 150 n¡9-10, 627-639.

LIX-HOFNUNG M. & SHAPIRO J. 1999. Introduction.
Research in Microbiology, 150 n¡9-10, 577-578.

LX-QUILLARDET P. & HOFNUNG M. 1999. The detection of the primary cellular responses to
genotoxic agents by the SOS Chromotest. In Trends in environmental mutagenesis. Chapt. 4. R.
C. Sobti, G. Obe, P. Quillardet (Eds), Tausco Book, New-Delhi, India, pp. 53-59.

LXI-QUILLARDET P. & HOFNUNG M. 1999. Use of the SOS Chromotest for the diagnosis of
genotoxic agents. In Trends in environmental mutagenesis. Chapt. 5. R. C. Sobti, G. Obe, P.
Quillardet (Eds), Tausco Book, New-Delhi, India, pp. 61-66.

  

2000

184-CHARBIT A., ANDERSEN C., WANG J., SCHIFFLER B., MICHEL V., BENZ R. &
HOFNUNG M. 2000. In vivo and in vitro studies of transmembrane §-strands deletion, insertion
or substitution mutants of the Escherichia coli K 12 maltoporin.
Molecular Microbiology, 35 n¡4, 777-790.

185-WANG J., HOFNUNG M. & CHARBIT A. 2000. C-terminal portion of the tail fibre
protein of bacteriophage lambda is responsible for the binding to LamB, its receptor at the surface
of Escherichia coli K12. Journal of Bacteriology, 182 n¡2, 508-512.

186-MOUREZ M., JEHANNO M., HOFNUNG M. & DASSA E. 2000. Rle, fonctionnement et
structure des transporteurs ATP Binding Cassette (ABC). Mdecine/Sciences, 16 n¡3, 386-394.

187-HIMMELRICH H., LO-MAN R., WINTER N., GUERMONPREZ P., SEDLIK C.,
ROJAS M., MONNAIE D., GHEORGHIU M., LAGRANDERIE M., HOFNUNG M.,
GICQUEL B., CLEMENT J.-M. & LECLERC C. 2000. Immune responses induced by
recombinant BCG strains according to level of production of a foreign antigen : MalE. Vaccine, 18
2636-2647.

188-LO-MAN R., LANGEVELD J. P. M., DERIAUD E., JEHANNO M., ROJAS M.,
CLEMENT J.-M., MELOEN R.H., HOFNUNG M. & LECLERC C. 2000. Extending the CD4+
T cell epitope specificity of the Th1 immune response to an antigen using a salmonella enterica
serovar typhimurium delivery vehicle. Infection and Immunity, 68 n¡6, 3079-3089.

189-QUILLARDET P., MICHEL V., ARRAULT X., HOFNUNG M., TOUATI E. 2000.
Mutagenic properties of a nitrofuran, 7-methoxy-2-nitronaphtho[2,1-b]-furan (R7000) in lacI
transgenic mice. Mutation Research, 470 n¡2, 177-188.

190-TOUATI E., HOFNUNG M., THIBERGE J.-M., MICHEL V., LABIGNE A. & JENKS
P. 2000. Short-term infection with Helicobacter pylori and 1 week exposure to metronidazole does
not enhance gastric mutation frequency in transgenic mice. Journal of Antimicrobial
Chemotherapy, 46,987-992.

191-COEFFIER E., CLEMENT J.-M., CUSSAC V., KHODAEI-BOORANE N., JEHANNO
M., ROJAS M., DRIDI A., LATOUR M., EL HABIB R., BARRE-SINOUSSI F., HOFNUNG
M. & LECLERC C. 2000. Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA
inserted into permissive sites of the MalE protein. Vaccine, 19 n¡7-8, 684-693.

WANG J., HUANG P., CAO Y., HOFNUNG M. & CHARBIT A. 2000. Study and application
of the specific transportation system for maltose and maltodextrin in E. coli and its porin protein,
LamB (article en chinois). Microbiology (revue chinoise), (Accept Juin 2000).