genome map and supplemental information
- Circular genome maps of L. monocytogenes EGDe and L. innocua CLIP11262 showing the position and orientation of genes

- Distribution of the 270 L. monocytogenesEGDe-specific and the 149 L. innocua CLIP11262-specific genes within the different functional categories

- Comparison of the region containing the virulence gene cluster of L. monocytogenes and the homologous regions of the L. innocua and the B. subtilis genomes
Circular genome maps of L. monocytogenes EGDe and L. innocua CLIP11262 showing the position and orientation of genes.
From the outside : circle 1 and 2: L. innocua and L. monocytogenes genes on the + and – strands, respectively; Color code : green, L. innocua genes ; red, L. monocytogenes genes ; black, genes specific for L. monocytogenes or L. innocua, respectively ; orange, rRNA operons; purple, prophages; Numbers on the second circle indicate the position of known virulence genes: 1 virulence locus (prfA-plcA-hly-mpl-actA-plcB); 2 clpC; 3 inlAB; 4 iap, 5 dal, 6 clpE 7 lisRK; 8 dat; 9 inlC, 10 arpJ, 11 clpP, 12 ami, 13 bvrABC; circle 3: G/C bias (G+C/G-C) of L. monocytogenes ; circle 4: represents G+C content of L. monocytogenes with <32.5% G+C in light yellow, between 32.5% and 43.5% in yellow and with >43.5% G+C in dark yellow. The scale in Mb is indicated on the outside of the genomes with the origin of replication being at position 0.

Top
Distribution of the 270 L. monocytogenesEGDe-specific and the 149 L. innocua CLIP11262-specific genes within the different functional categories. Genes were considered as strain specific for L. monocytogenes when they had no ortholog in L. innocua and vice versa.
Top
Comparison of the region containing the virulence gene cluster of L. monocytogenes and the homologous regions of the L. innocua and the B. subtilis genomes. Open blue boxes and arrows, orthologs among the three genomes Solid red boxes and arrows, virulence gene cluster; solid yellow boxes and arrows, genes absent from B. subtilis. A: Scheme generated by GenomeScout software (LION Bioscience). B: Enlargement of the region containing the virulence gene cluster.
Top
Laboratoire GMP, Institut Pasteur, Département de Biologie Moléculaire, 25 rue du Dr Roux, 75724 Paris Cedex 15, France. Fax : 33 1 45 68 87 86