> Pathogénie microbienne moléculaire - INSERM U389
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1. Sansonetti, P. J., David, M., Toucas, M. 1980
Corrélation entre la perte d'ADN plasmidique et le passage de la phase I virulente à la phase II avirulente chez Shigella sonnei.
C. R. Acad. Sci. Paris, T. 290 (D), 879-882
2. Sansonetti PJ, Kopecko DJ, Formal SB.
Shigella sonnei plasmids: evidence that a large plasmid is necessary for virulence.
Infect Immun. 1981 Oct;34(1):75-83.
3. Sansonetti PJ, Kopecko DJ, Formal SB.
Involvement of a plasmid in the invasive ability of Shigella flexneri.
Infect Immun. 1982 Mar;35(3):852-60.
4. Sansonetti PJ, d'Hauteville H, Formal SB, Toucas M.
Plasmid-mediated invasiveness of "Shigella-like" Escherichia coli.
Ann Microbiol (Paris). 1982 May-Jun;133(3):351-5.
5. Sansonetti PJ, Hale TL, Dammin GJ, Kapfer C, Collins HH Jr, Formal SB.
Alterations in the pathogenicity of Escherichia coli K-12 after transfer of plasmid and chromosomal genes from Shigella flexneri.
Infect Immun. 1983 Mar;39(3):1392-402.
6. Hale TL, Sansonetti PJ, Schad PA, Austin S, Formal SB.
Characterization of virulence plasmids and plasmid-associated outer membrane proteins in Shigella flexneri, Shigella sonnei, and Escherichia coli.
Infect Immun. 1983 Apr;40(1):340-50.
7. Sansonetti PJ, d'Hauteville H, Ecobichon C, Pourcel C.
Molecular comparison of virulence plasmids in Shigella and enteroinvasive Escherichia coli.
Ann Microbiol (Paris). 1983 May-Jun;134A(3):295-318.
8. Formal SB, Hale TL, Sansonetti PJ.
Invasive enteric pathogens.
Rev Infect Dis. 1983 Sep-Oct;5 Suppl 4:S702-7.
9. Boileau CR, d'Hauteville HM, Sansonetti PJ.
DNA hybridization technique to detect Shigella species and enteroinvasive escherichia coli.
J Clin Microbiol. 1984 Nov;20(5):959-61.
10. SANSONETTI, P. J., HALE, T. L., OAKS, E. V. 1985
Genetics of virulence in Enteroinvasive E. coli.
Microbiology. New concepts in the pathogenesis of Escherichia coli diarrhea.

American Society for Microbiology. Ed. , pp. 74-77
11. Maurelli AT, Baudry B, d'Hauteville H, Hale TL, Sansonetti PJ.
Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella flexneri.
Infect Immun. 1985 Jul;49(1):164-71.
12. Sansonetti PJ, Ryter A, Clerc P, Maurelli AT, Mounier J.
Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis.
Infect Immun. 1986 Feb;51(2):461-9.
13. Gaillard JL, Berche P, Sansonetti P.
Transposon mutagenesis as a tool to study the role of hemolysin in the virulence of Listeria monocytogenes.
Infect Immun. 1986 Apr;52(1):50-5.
14. Clerc P, Baudry B, Sansonetti PJ.
Plasmid-mediated contact haemolytic activity in Shigella species: correlation with penetration into HeLa cells.
Ann Inst Pasteur Microbiol. 1986 May-Jun;137A(3):267-78.
15. Clerc P, Ryter A, Mounier J, Sansonetti PJ.
Plasmid-mediated intracellular multiplication of Shigella flexneri.
Ann Inst Pasteur Microbiol. 1986 May-Jun;137A(3):315-20.
16. Nassif X, Sansonetti PJ.
Correlation of the virulence of Klebsiella pneumoniae K1 and K2 with the presence of a plasmid encoding aerobactin.
Infect Immun. 1986 Dec;54(3):603-8.
17. SANSONETTI, P.J., FORMAL, S.B., HALE, T.L. 1986
Expression of virulence-associated plasmids in Shigella flexneri minicells.
Advanced in Research on cholera and Related Diarrheas, 3:67-74
18. Lafont JP, Dho M, D'Hauteville HM, Bree A, Sansonetti PJ.
Presence and expression of aerobactin genes in virulent avian strains of Escherichia coli.
Infect Immun. 1987 Jan;55(1):193-7.
19. Clerc PL, Ryter A, Mounier J, Sansonetti PJ.
Plasmid-mediated early killing of eucaryotic cells by Shigella flexneri as studied by infection of J774 macrophages.
Infect Immun. 1987 Mar;55(3):521-7.
20. Berche P, Gaillard JL, Sansonetti PJ.
Intracellular growth of Listeria monocytogenes as a prerequisite for in vivo induction of T cell-mediated immunity.
J Immunol. 1987 Apr 1;138(7):2266-71.
21. Sansonetti PJ, Mounier J.
Metabolic events mediating early killing of host cells infected by Shigella flexneri.
Microb Pathog. 1987 Jul;3(1):53-61.
22. Nassif X, Mazert MC, Mounier J, Sansonetti PJ.
Evaluation with an iuc::Tn10 mutant of the role of aerobactin production in the virulence of Shigella flexneri.
Infect Immun. 1987 Sep;55(9):1963-9.
23. Clerc P, Sansonetti PJ.
Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation.
Infect Immun. 1987 Nov;55(11):2681-8.
24. Gaillard JL, Berche P, Mounier J, Richard S, Sansonetti P.
In vitro model of penetration and intracellular growth of Listeria monocytogenes in the human enterocyte-like cell line Caco-2.
Infect Immun. 1987 Nov;55(11):2822-9.
25. Baudry B, Maurelli AT, Clerc P, Sadoff JC, Sansonetti PJ.
Localization of plasmid loci necessary for the entry of Shigella flexneri into HeLa cells, and characterization of one locus encoding four immunogenic polypeptides.
J Gen Microbiol. 1987 Dec;133 ( Pt 12):3403-13.
26. Clerc P, Baudry B, Sansonetti PJ.
Molecular mechanisms of entry, intracellular multiplication and killing of host cells by shigellae.
Curr Top Microbiol Immunol. 1988;138:3-13
27. Gaillard, J.L., Berche, P., Mounier, J., Richard, S., Sansonetti, P.J. 1987
Penetration of Listeria monocytogenes into the host : a crucial step of the infectious process.
3rd Forum in Microbiology, Ann. Inst. Pasteur/Microbiol., 138:259-264
28. Maurelli AT, Sansonetti PJ.
Genetic determinants of Shigella pathogenicity.
Annu Rev Microbiol. 1988;42:127-50.
29. Sansonetti PJ.
Molecular basis of invasion of eucaryotic cells by Shigella.
Antonie Van Leeuwenhoek. 1988;54(5):389-93.
30. Maurelli AT, Sansonetti PJ.
Identification of a chromosomal gene controlling temperature-regulated expression of Shigella virulence.
Proc Natl Acad Sci U S A. 1988 Apr;85(8):2820-4.
31. Baudry B, Kaczorek M, Sansonetti PJ.
Nucleotide sequence of the invasion plasmid antigen B and C genes (ipaB and ipaC) of Shigella flexneri.
Microb Pathog. 1988 May;4(5):345-57.
32. Fontaine A, Arondel J, Sansonetti PJ.
Role of Shiga toxin in the pathogenesis of bacillary dysentery, studied by using a Tox- mutant of Shigella dysenteriae 1.
Infect Immun. 1988 Dec;56(12):3099-109.
33. Clerc, P., Baudry, B., Sansonetti, P. J. 1988
Molecular mechanisms of entry, intracellular multiplication and killing of host cells by Shigellae.
In Current Topics in Microbiology and Immunology, Intracellular Bacteria, W. Goebel Ed. Springer Verlag, pp. 3-13
34. Nassif X, Fournier JM, Arondel J, Sansonetti PJ.
Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor.
Infect Immun. 1989 Feb;57(2):546-52.
35. Bernardini ML, Mounier J, d'Hauteville H, Coquis-Rondon M, Sansonetti PJ.
Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin.
Proc Natl Acad Sci U S A. 1989 May;86(10):3867-71.
36. Clerc PL, Berthon B, Claret M, Sansonetti PJ.
Internalization of Shigella flexneri into HeLa cells occurs without an increase in cytosolic Ca2+ concentration.
Infect Immun. 1989 Sep;57(9):2919-22.
37. Sansonetti PJ, Arondel J.
Construction and evaluation of a double mutant of Shigella flexneri as a candidate for oral vaccination against shigellosis.
Vaccine. 1989 Oct;7(5):443-50.
38. Nassif X, Honore N, Vasselon T, Cole ST, Sansonetti PJ.
Positive control of colanic acid synthesis in Escherichia coli by rmpA and rmpB, two virulence-plasmid genes of Klebsiella pneumoniae.
Mol Microbiol. 1989 Oct;3(10):1349-59.
39. Clerc PL, Sansonetti PJ.
Evidence for clathrin mobilization during directed phagocytosis of Shigella flexneri by HEp2 cells.
Microb Pathog. 1989 Nov;7(5):329-36.
40. Dacosta B, Ryter A, Mounier J, Sansonetti P.
Immunodetection of lipopolysaccharide in macrophages during the processing of non invasive Shigella dysenteriae.
Biol Cell. 1990;69(3):171-8.
41. Franzon VL, Arondel J, Sansonetti PJ.
Contribution of superoxide dismutase and catalase activities to Shigella flexneri pathogenesis.
Infect Immun. 1990 Feb;58(2):529-35.
42. Mounier J, Ryter A, Coquis-Rondon M, Sansonetti PJ.
Intracellular and cell-to-cell spread of Listeria monocytogenes involves interaction with F-actin in the enterocytelike cell line Caco-2.
Infect Immun. 1990 Apr;58(4):1048-58.
43. Dacosta B, Sansonetti P, Ryter A.
Immunolabelling of Shiga toxin in macrophages infected with Shigella dysenteriae 1.
Res Microbiol. 1990 Jun;141(5):543-9.
44. Fontaine A, Arondel J, Sansonetti PJ.
Construction and evaluation of live attenuated vaccine strains of Shigella flexneri and Shigella dysenteriae 1.
Res Microbiol. 1990 Sep-Oct;141(7-8):907-12.
45. Bernardini ML, Fontaine A, Sansonetti PJ.
The two-component regulatory system ompR-envZ controls the virulence of Shigella flexneri.
J Bacteriol. 1990 Nov;172(11):6274-81.
46. Kuhn M, Prevost MC, Mounier J, Sansonetti PJ.
A nonvirulent mutant of Listeria monocytogenes does not move intracellularly but still induces polymerization of actin.
Infect Immun. 1990 Nov;58(11):3477-86.
47. Vasselon T, Sansonetti PJ, Nassif X.
Nucleotide sequence of rmpB, a Klebsiella pneumoniae gene that positively controls, colanic biosynthesis in Escherichia coli.
Res Microbiol. 1991 Jan;142(1):47-54.
48. Sansonetti PJ.
Genetic and molecular basis of epithelial cell invasion by Shigella species.
Rev Infect Dis. 1991 Mar-Apr;13 Suppl 4:S285-92.
49. Vasselon T, Mounier J, Prevost MC, Hellio R, Sansonetti PJ.
Stress fiber-based movement of Shigella flexneri within cells.
Infect Immun. 1991 May;59(5):1723-32.
50. Sansonetti PJ, Arondel J, Fontaine A, d'Hauteville H, Bernardini ML.
OmpB (osmo-regulation) and icsA (cell-to-cell spread) mutants of Shigella flexneri: vaccine candidates and probes to study the pathogenesis of shigellosis.
Vaccine. 1991 Jun;9(6):416-22.
51. Arhets P, Rahim Z, Raymond-Denise A, Sansonetti P, Guillen N.
Identification of a myosin heavy chain gene from Entamoeba histolytica.
Arch Med Res. 1992;23(2):41-3.
52. Verdon R, Mirelman D, Sansonetti PJ.
A model of interaction between Entamoeba histolytica and Shigella flexneri.
Res Microbiol. 1992 Jan;143(1):67-74.
53. Sansonetti PJ.
Molecular and cellular biology of Shigella flexneri invasiveness: from cell assay systems to shigellosis.
Curr Top Microbiol Immunol. 1992;180:1-19.
54. Mounier J, Vasselon T, Hellio R, Lesourd M, Sansonetti PJ.
Shigella flexneri enters human colonic Caco-2 epithelial cells through the basolateral pole.
Infect Immun. 1992 Jan;60(1):237-48.
55. Vasselon T, Mounier J, Hellio R, Sansonetti PJ.
Movement along actin filaments of the perijunctional area and de novo polymerization of cellular actin are required for Shigella flexneri colonization of epithelial Caco-2 cell monolayers.
Infect Immun. 1992 Mar;60(3):1031-40.
56. d'Hauteville H, Sansonetti PJ.
Phosphorylation of IcsA by cAMP-dependent protein kinase and its effect on intracellular spread of Shigella flexneri.
Mol Microbiol. 1992 Apr;6(7):833-41.
57. Phalipon A, Arondel J, Nato F, Rouyre S, Mazie JC, Sansonetti PJ.
Identification and characterization of B-cell epitopes of IpaC, an invasion-associated protein of Shigella flexneri.
Infect Immun. 1992 May;60(5):1919-26.
58. High N, Mounier J, Prevost MC, Sansonetti PJ.
IpaB of Shigella flexneri causes entry into epithelial cells and escape from the phagocytic vacuole.
EMBO J. 1992 May;11(5):1991-9.
59. Allaoui A, Mounier J, Prevost MC, Sansonetti PJ, Parsot C.
icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread.
Mol Microbiol. 1992 Jun;6(12):1605-16.
60. Zychlinsky A, Prevost MC, Sansonetti PJ.
Shigella flexneri induces apoptosis in infected macrophages.
Nature. 1992 Jul 9;358(6382):167-9.
61. Prevost MC, Lesourd M, Arpin M, Vernel F, Mounier J, Hellio R, Sansonetti PJ.
Unipolar reorganization of F-actin layer at bacterial division and bundling of actin filaments by plastin correlate with movement of Shigella flexneri within HeLa cells.
Infect Immun. 1992 Oct;60(10):4088-99.
62. Allaoui A, Sansonetti PJ, Parsot C
MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasins, is homologous to YscJ, a secretion factor of the Yersinia Yop proteins.
J Bacteriol. 1992 Dec;174(23):7661-9.
63. Allaoui A, Sansonetti PJ, Parsot C.
MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasins.
Mol Microbiol. 1993 Jan;7(1):59-68.
64. Rahim Z, Raymond-Denise A, Sansonetti P, Guillen N.
Localization of myosin heavy chain A in the human pathogen Entamoeba histolytica.
Infect Immun. 1993 Mar;61(3):1048-54.
65. Goldberg MB, Barzu O, Parsot C, Sansonetti PJ.
Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement.
J Bacteriol. 1993 Apr;175(8):2189-96.
66. Gbarah A, Mirelman D, Sansonetti PJ, Verdon R, Bernhard W, Sharon N.
Shigella flexneri transformants expressing type 1 (mannose-specific) fimbriae bind to, activate, and are killed by phagocytic cells.
Infect Immun. 1993 May;61(5):1687-93.
67. Allaoui A, Menard R, Sansonetti PJ, Parsot C.
Characterization of the Shigella flexneri ipgD and ipgF genes, which are located in the proximal part of the mxi locus.
Infect Immun. 1993 May;61(5):1707-14.

68. Raymond-Denise A, Sansonetti P, Guillen N.
Identification and characterization of a myosin heavy chain gene (mhcA) from the human parasitic pathogen Entamoeba histolytica.
Mol Biochem Parasitol. 1993 May;59(1):123-31.

69. Sansonetti PJ.
Molecular mechanisms of cell and tissue invasion by Shigella flexneri.
Infect Agents Dis. 1993 Aug;2(4):201-6.
70. Goldberg MB, Barzu O, Parsot C, Sansonetti PJ.
Unipolar localization and ATPase activity of IcsA, a Shigella flexneri protein involved in intracellular movement.
Infect Agents Dis. 1993 Aug;2(4):210-1.
71. Zychlinsky A, Kenny B, Prevost MC, Holland IB, Sansonetti PJ.
The ipaB gene of Shigella flexneri and macrophage-programmed cell death.
Infect Agents Dis. 1993 Aug;2(4):212-4.
72. Barzu S, Nato F, Rouyre S, Mazie JC, Sansonetti P, Phalipon A.
Characterization of B-cell epitopes on IpaB, an invasion-associated antigen of Shigella flexneri: identification of an immunodominant domain recognized during natural infection.
Infect Immun. 1993 Sep;61(9):3825-31.
73. Bernardini ML, Sanna MG, Fontaine A, Sansonetti PJ.
OmpC is involved in invasion of epithelial cells by Shigella flexneri.
Infect Immun. 1993 Sep;61(9):3625-35.
74. Menard R, Sansonetti PJ, Parsot C.
Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells.
J Bacteriol. 1993 Sep;175(18):5899-906.
75. Sansonetti PJ.
Bacterial pathogens, from adherence to invasion: comparative strategies.
Med Microbiol Immunol (Berl). 1993 Nov;182(5):223-32
76. Goldberg MB, Sansonetti PJ.
Shigella subversion of the cellular cytoskeleton: a strategy for epithelial colonization.
Infect Immun. 1993 Dec;61(12):4941-6
77. Parsot C.
Shigella flexneri: genetics of entry and intercellular dissemination in epithelial cells.
Curr Top Microbiol Immunol. 1994;192:217-41.
78. Menard R, Sansonetti PJ.
Shigella flexneri: isolation of noninvasive mutants of gram-negative pathogens.
Methods Enzymol. 1994;236:493-509.
79. Perdomo JJ, Gounon P, Sansonetti PJ.
Polymorphonuclear leukocyte transmigration promotes invasion of colonic epithelial monolayer by Shigella flexneri.
J Clin Invest. 1994 Feb;93(2):633-43.
80. Zychlinsky A, Kenny B, Menard R, Prevost MC, Holland IB, Sansonetti PJ.
IpaB mediates macrophage apoptosis induced by Shigella flexneri.
Mol Microbiol. 1994 Feb;11(4):619-27.
81. Sansonetti PJ, Mounier J, Prevost MC, Mege RM.
Cadherin expression is required for the spread of Shigella flexneri between epithelial cells.
Cell. 1994 Mar 11;76(5):829-39.
82. Sansonetti PJ.
Shigella flexneri: from in vitro invasion of epithelial cells to infection of the intestinal barrier.
Biochem Soc Trans. 1994 May;22(2):295-8.
83. Zychlinsky A, Perdomo JJ, Sansonetti PJ.
Molecular and cellular mechanisms of tissue invasion by Shigella flexneri.
Ann N Y Acad Sci. 1994 Aug 15;730:197-208.
84. Phalipon A, Michetti P, Kaufmann M, Cavaillon JM, Huerre M, Kraehenbuhl JP, Sansonetti PJ.
Protection against invasion of the mouse pulmonary epithelium by a monoclonal IgA directed against Shigella flexneri lipopolysaccharide.
Ann N Y Acad Sci. 1994 Aug 15;730:356-8.
85. Zychlinsky A, Fitting C, Cavaillon JM, Sansonetti PJ.
Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri.
J Clin Invest. 1994 Sep;94(3):1328-32.
86. Perdomo OJ, Cavaillon JM, Huerre M, Ohayon H, Gounon P, Sansonetti PJ.
Acute inflammation causes epithelial invasion and mucosal destruction in experimental shigellosis.
J Exp Med. 1994 Oct 1;180(4):1307-19.
87. Menard R, Sansonetti P, Parsot C, Vasselon T.
Extracellular association and cytoplasmic partitioning of the IpaB and IpaC invasins of S. flexneri.
Cell. 1994 Nov 4;79(3):515-25.
88. Menard R, Sansonetti P, Parsot C.
The secretion of the Shigella flexneri Ipa invasins is activated by epithelial cells and controlled by IpaB and IpaD.
EMBO J. 1994 Nov 15;13(22):5293-302.
89. Goldberg MB, Theriot JA, Sansonetti PJ.
Regulation of surface presentation of IcsA, a Shigella protein essential to intracellular movement and spread, is growth phase dependent.
Infect Immun. 1994 Dec;62(12):5664-8.
90. Kraehenbuhl JP, Kerneis S, Berdoz J, Corthesy B, Rindisbacher L, Corthesy-Theulaz I, Phalipon A, Neutra MR, Pringault E.
Molecular events in production and transport of secretory IgA: a basis for design of reagents for passive immune protection.
Vet Res. 1995;26(3):231-2.
91. Bianchi E, Folgori A, Wallace A, Nicotra M, Acali S, Phalipon A, Barbato G, Bazzo R, Cortese R, Felici F, et al.
A conformationally homogeneous combinatorial peptide library.
J Mol Biol. 1995 Mar 24;247(2):154-60.
92. Parsot C, Menard R, Gounon P, Sansonetti PJ.
Enhanced secretion through the Shigella flexneri Mxi-Spa translocon leads to assembly of extracellular proteins into macromolecular structures.
Mol Microbiol. 1995 Apr;16(2):291-300.
93. Adam T, Arpin M, Prevost MC, Gounon P, Sansonetti PJ.
Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells.
J Cell Biol. 1995 Apr;129(2):367-81.
94. Dehio C, Prevost MC, Sansonetti PJ.
Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway.
EMBO J. 1995 Jun 1;14(11):2471-82.
95. Phalipon A, Sansonetti P.
Live attenuated Shigella flexneri mutants as vaccine candidates against shigellosis and vectors for antigen delivery.
Biologicals. 1995 Jun;23(2):125-34.
96. Benjelloun-Touimi Z, Sansonetti PJ, Parsot C.
SepA, the major extracellular protein of Shigella flexneri: autonomous secretion and involvement in tissue invasion.
Mol Microbiol. 1995 Jul;17(1):123-35.
97. Sansonetti PJ, Arondel J, Cavaillon JM, Huerre M.
Role of interleukin-1 in the pathogenesis of experimental shigellosis.
J Clin Invest. 1995 Aug;96(2):884-92.
98. Allaoui A, Sansonetti PJ, Menard R, Barzu S, Mounier J, Phalipon A, Parsot C.
MxiG, a membrane protein required for secretion of Shigella spp. Ipa invasins: involvement in entry into epithelial cells and in intercellular dissemination.
Mol Microbiol. 1995 Aug;17(3):461-70.
99. Hermant D, Menard R, Arricau N, Parsot C, Popoff MY.
Functional conservation of the Salmonella and Shigella effectors of entry into epithelial cells.
Mol Microbiol. 1995 Aug;17(4):781-9.
100. Phalipon A, Kaufmann M, Michetti P, Cavaillon JM, Huerre M, Sansonetti P, Kraehenbuhl JP.
Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis.
J Exp Med. 1995 Sep 1;182(3):769-78.
101. Arhets P, Gounon P, Sansonetti P, Guillen N.
Myosin II is involved in capping and uroid formation in the human pathogen Entamoeba histolytica.
Infect Immun. 1995 Nov;63(11):4358-67.
102. Kocks C, Marchand JB, Gouin E, d'Hauteville H, Sansonetti PJ, Carlier MF, Cossart P.
The unrelated surface proteins ActA of Listeria monocytogenes and IcsA of Shigella flexneri are sufficient to confer actin-based motility on Listeria innocua and Escherichia coli respectively.
Mol Microbiol. 1995 Nov;18(3):413-23.
103. Parsot C, Sansonetti PJ.
Invasion and the pathogenesis of Shigella infections.
Curr Top Microbiol Immunol. 1996;209:25-42.
104. d'Hauteville H, Dufourcq Lagelouse R, Nato F, Sansonetti PJ.
Lack of cleavage of IcsA in Shigella flexneri causes aberrant movement and allows demonstration of a cross-reactive eukaryotic protein.
Infect Immun. 1996 Feb;64(2):511-7.
105. Menard R, Prevost MC, Gounon P, Sansonetti P, Dehio C
The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells.
Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1254-8.
106. Renesto P, Mounier J, Sansonetti PJ.
Induction of adherence and degranulation of polymorphonuclear leukocytes: a new expression of the invasive phenotype of Shigella flexneri.
Infect Immun. 1996 Mar;64(3):719-23.
107. Barzu S, Fontaine A, Sansonetti P, Phalipon A.
Induction of a local anti-IpaC antibody response in mice by use of a Shigella flexneri 2a vaccine candidate: implications for use of IpaC as a protein carrier.
Infect Immun. 1996 Apr;64(4):1190-6.
108. Menard R, Dehio C, Sansonetti PJ.
Bacterial entry into epithelial cells: the paradigm of Shigella.
Trends Microbiol. 1996 Jun;4(6):220-6.
109. Adam T, Giry M, Boquet P, Sansonetti P.
Rho-dependent membrane folding causes Shigella entry into epithelial cells.
EMBO J. 1996 Jul 1;15(13):3315-21.
110. Mantis N, Prevost MC, Sansonetti P.
Analysis of epithelial cell stress response during infection by Shigella flexneri.
Infect Immun. 1996 Jul;64(7):2474-82.
111. Sansonetti PJ, Arondel J, Cantey JR, Prevost MC, Huerre M.
Infection of rabbit Peyer's patches by Shigella flexneri: effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium.
Infect Immun. 1996 Jul;64(7):2752-64.
112. Sansonetti P, Phalipon A.
Shigellosis: from molecular pathogenesis of infection to protective immunity and vaccine development.
Res Immunol. 1996 Oct-Dec;147(8-9):595-602.
113. Mantis NJ, Sansonetti PJ.
The nadB gene of Salmonella typhimurium complements the nicotinic acid auxotrophy of Shigella flexneri.
Mol Gen Genet. 1996 Oct 16;252(5):626-9.
114. Zychlinsky A, Thirumalai K, Arondel J, Cantey JR, Aliprantis AO, Sansonetti PJ.
In vivo apoptosis in Shigella flexneri infections.
Infect Immun. 1996 Dec;64(12):5357-65.
115. Vargas M, Sansonetti P, Guillen N
Identification and cellular localization of the actin-binding protein ABP-120 from Entamoeba histolytica.
Mol Microbiol. 1996 Dec;22(5):849-57.
116. Corthesy B, Kaufmann M, Phalipon A, Peitsch M, Neutra MR, Kraehenbuhl JP.
A pathogen-specific epitope inserted into recombinant secretory immunoglobulin A is immunogenic by the oral route.
J Biol Chem. 1996 Dec 27;271(52):33670-7.
117. Guillen N, Sansonetti P.
Rac G, a small GTPase, regulates capping of surface receptors in Entamoeba histolytica.
Arch Med Res. 1997;28 Spec No:129-31.
118. Vargas MA, Voigt H, Sansonetti P, Guillen N.
The tail domain of Entamoeba histolytica myosin IB bind F-actin.
Arch Med Res. 1997;28 Spec No:137-8.
119. De Geyter C, Vogt B, Benjelloun-Touimi Z, Sansonetti PJ, Ruysschaert JM, Parsot C, Cabiaux V.
Purification of IpaC, a protein involved in entry of Shigella flexneri into epithelial cells and characterization of its interaction with lipid membranes.
FEBS Lett. 1997 Jan 3;400(2):149-54.
120. Mounier J, Bahrani FK, Sansonetti PJ.
Secretion of Shigella flexneri Ipa invasins on contact with epithelial cells and subsequent entry of the bacterium into cells are growth stage dependent.
Infect Immun. 1997 Feb;65(2):774-82.
121. Egile C, d'Hauteville H, Parsot C, Sansonetti PJ.
SopA, the outer membrane protease responsible for polar localization of IcsA in Shigella flexneri.
Mol Microbiol. 1997 Mar;23(5):1063-73.
122. Barzu S, Benjelloun-Touimi Z, Phalipon A, Sansonetti P, Parsot C.
Functional analysis of the Shigella flexneri IpaC invasin by insertional mutagenesis.
Infect Immun. 1997 May;65(5):1599-605.
123. Zychlinsky A, Sansonetti PJ.
Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death?
Trends Microbiol. 1997 May;5(5):201-4.
124. Vargas M, Voigt H, Sansonetti P, Guillen N.
Molecular characterization of myosin IB from the lower eukaryote Entamoeba histolytica, a human parasite.
Mol Biochem Parasitol. 1997 May;86(1):61-73.
125. Tran Van Nhieu G, Ben-Ze'ev A, Sansonetti PJ.
Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin.
EMBO J. 1997 May 15;16(10):2717-29.
126. Zychlinsky A, Sansonetti P.
Perspectives series: host/pathogen interactions. Apoptosis in bacterial pathogenesis.
J Clin Invest. 1997 Aug 1;100(3):493-5. Review. No abstract available.
127. Bahrani FK, Sansonetti PJ, Parsot C.
Secretion of Ipa proteins by Shigella flexneri: inducer molecules and kinetics of activation.
Infect Immun. 1997 Oct;65(10):4005-10.
128. Renesto P, Sansonetti PJ, Guillen N.
Interaction between Entamoeba histolytica and intestinal epithelial cells involves a CD44 cross-reactive protein expressed on the parasite surface.
Infect Immun. 1997 Oct;65(10):4330-3.
129. Phalipon A, Folgori A, Arondel J, Sgaramella G, Fortugno P, Cortese R, Sansonetti PJ, Felici F.
Induction of anti-carbohydrate antibodies by phage library-selected peptide mimics.
Eur J Immunol. 1997 Oct;27(10):2620-5.
130. Beatty WL, Sansonetti PJ.
Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes.
Infect Immun. 1997 Nov;65(11):4395-404.
131. Hilbi H, Zychlinsky A, Sansonetti PJ.
Macrophage apoptosis in microbial infections.
Parasitology. 1997;115 Suppl:S79-87.
132. Sansonetti PJ.
Slaying the Hydra all at once or head by head?
Nat Med. 1998 May;4(5 Suppl):499-500.
133. Barzu S, Arondel J, Guillot S, Sansonetti PJ, Phalipon A
Immunogenicity of IpaC-hybrid proteins expressed in the Shigella flexneri 2a vaccine candidate SC602.
Infect Immun. 1998 Jan;66(1):77-82.
134. Demers B, Sansonetti PJ, Parsot C.
Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins.
EMBO J. 1998 May 15;17(10):2894-903.
135. Guillen N, Boquet P, Sansonetti P.
The small GTP-binding protein RacG regulates uroid formation in the protozoan parasite Entamoeba histolytica.
J Cell Sci. 1998 Jun;111 ( Pt 12):1729-39.
136. Arhets P, Olivo JC, Gounon P, Sansonetti P, Guillen N
Virulence and functions of myosin II are inhibited by overexpression of light meromyosin in Entamoeba histolytica.
Mol Biol Cell. 1998 Jun;9(6):1537-47.
137. Benjelloun-Touimi Z, Tahar MS, Montecucco C, Sansonetti PJ, Parsot C.
SepA, the 110 kDa protein secreted by Shigella flexneri: two-domain structure and proteolytic activity.
Microbiology. 1998 Jul;144 ( Pt 7):1815-22.
138. Boisgerault F, Mounier J, Tieng V, Stolzenberg MC, Khalil-Daher I, Schmid M, Sansonetti P, Charron D, Toubert A.
Alteration of HLA-B27 peptide presentation after infection of transfected murine L cells by Shigella flexneri.
Infect Immun. 1998 Sep;66(9):4484-90.
139. Dumenil G, Olivo JC, Pellegrini S, Fellous M, Sansonetti PJ, Nhieu GT.
Interferon alpha inhibits a Src-mediated pathway necessary for Shigella-induced cytoskeletal rearrangements in epithelial cells.
J Cell Biol. 1998 Nov 16;143(4):1003-12.
140. Hilbi H, Moss JE, Hersh D, Chen Y, Arondel J, Banerjee S, Flavell RA, Yuan J, Sansonetti PJ, Zychlinsky A.
Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB.
J Biol Chem. 1998 Dec 4;273(49):32895-900.
141. Sansonetti PJ.
Pathogenesis of shigellosis: from molecular and cellular biology of epithelial cell invasion to tissue inflammation and vaccine development.
Jpn J Med Sci Biol. 1998;51 Suppl:S69-80. Review. No abstract available.
142. Phalipon A, Sansonetti PJ.
Microbial-host interactions at mucosal sites. Host response to pathogenic bacteria at mucosal sites.
Curr Top Microbiol Immunol. 1999;236:163-89.
143. Nhieu GT, Sansonetti PJ.
Mechanism of Shigella entry into epithelial cells.
Curr Opin Microbiol. 1999 Feb;2(1):51-5.
144. Sansonetti PJ, Tran Van Nhieu G, Egile C.
Rupture of the intestinal epithelial barrier and mucosal invasion by Shigella flexneri.
Clin Infect Dis. 1999 Mar;28(3):466-75.
145. Sansonetti PJ, Arondel J, Huerre M, Harada A, Matsushima K.
Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis.
Infect Immun. 1999 Mar;67(3):1471-80.
146. Voigt H, Olivo JC, Sansonetti P, Guillen N.
Myosin IB from Entamoeba histolytica is involved in phagocytosis of human erythrocytes.
J Cell Sci. 1999 Apr;112 ( Pt 8):1191-201.
147. Beatty WL, Meresse S, Gounon P, Davoust J, Mounier J, Sansonetti PJ, Gorvel JP.
Trafficking of Shigella lipopolysaccharide in polarized intestinal epithelial cells.
J Cell Biol. 1999 May 17;145(4):689-98.
148. Gouin E, Gantelet H, Egile C, Lasa I, Ohayon H, Villiers V, Gounon P, Sansonetti PJ, Cossart P.
A comparative study of the actin-based motilities of the pathogenic bacteria Listeria monocytogenes, Shigella flexneri and Rickettsia conorii.
J Cell Sci. 1999 Jun;112 ( Pt 11):1697-708.
149. Tran Van Nhieu G, Caron E, Hall A, Sansonetti PJ.
IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells.
EMBO J. 1999 Jun 15;18(12):3249-62.
150. Sansonetti PJ, Phalipon A.
M cells as ports of entry for enteroinvasive pathogens: mechanisms of interaction, consequences for the disease process.
Semin Immunol. 1999 Jun;11(3):193-203.
151. Skoudy A, Nhieu GT, Mantis N, Arpin M, Mounier J, Gounon P, Sansonetti P.
A functional role for ezrin during Shigella flexneri entry into epithelial cells.
J Cell Sci. 1999 Jul;112 ( Pt 13):2059-68.
152. Mounier J, Laurent V, Hall A, Fort P, Carlier MF, Sansonetti PJ, Egile C.
Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular motility.
J Cell Sci. 1999 Jul;112 ( Pt 13):2069-80.
153. Coster TS, Hoge CW, VanDeVerg LL, Hartman AB, Oaks EV, Venkatesan MM, Cohen D, Robin G, Fontaine-Thompson A, Sansonetti PJ, Hale TL.
Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602.
Infect Immun. 1999 Jul;67(7):3437-43.
154. Stephens RS, Sansonetti P, Sibley D
Cellular microbiology - a research agenda and an emerging discipline.
Cell Microbiol. 1999 Jul;1(1):1-2.
155. Forestier C, Moreno E, Meresse S, Phalipon A, Olive D, Sansonetti P, Gorvel JP.
Interaction of Brucella abortus lipopolysaccharide with major histocompatibility complex class II molecules in B lymphocytes.
Infect Immun. 1999 Aug;67(8):4048-54.
156. Egile C, Loisel TP, Laurent V, Li R, Pantaloni D, Sansonetti PJ, Carlier MF.
Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility.
J Cell Biol. 1999 Sep 20;146(6):1319-32.
157. Page AL, Ohayon H, Sansonetti PJ, Parsot C
The secreted IpaB and IpaC invasins and their cytoplasmic chaperone IpgC are required for intercellular dissemination of Shigella flexneri.
Cell Microbiol. 1999 Sep;1(2):183-93.
158. Kotloff KL, Winickoff JP, Ivanoff B, Clemens JD, Swerdlow DL, Sansonetti PJ, Adak GK, Levine MM.
Global burden of Shigella infections: implications for vaccine development and implementation of control strategies.
Bull World Health Organ. 1999;77(8):651-66.
159. Arondel J, Singer M, Matsukawa A, Zychlinsky A, Sansonetti PJ.
Increased interleukin-1 (IL-1) and imbalance between IL-1 and IL-1 receptor antagonist during acute inflammation in experimental Shigellosis.
Infect Immun. 1999 Nov;67(11):6056-66.
160. Bourdet-Sicard R, Rudiger M, Jockusch BM, Gounon P, Sansonetti PJ, Nhieu GT.
Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization.
EMBO J. 1999 Nov 1;18(21):5853-62.
161. Blocker A, Gounon P, Larquet E, Niebuhr K, Cabiaux V, Parsot C, Sansonetti P.
The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranes.
J Cell Biol. 1999 Nov 1;147(3):683-93.
162. Memet S, Laouini D, Epinat JC, Whiteside ST, Goudeau B, Philpott D, Kayal S, Sansonetti PJ, Berche P, Kanellopoulos J, Israel A.
IkappaBepsilon-deficient mice: reduction of one T cell precursor subspecies and enhanced Ig isotype switching and cytokine synthesis.
J Immunol. 1999 Dec 1;163(11):5994-6005.
163. Boquet P, Sansonetti PJ, Tran Van Nhieu G.
Rho GTP-binding proteins as targets for microbial pathogens.
Prog Mol Subcell Biol. 1999;22:183-99.
164. Dumenil G, Sansonetti P, Tran Van Nhieu G.
Src tyrosine kinase activity down-regulates Rho-dependent responses during Shigella entry into epithelial cells and stress fibre formation.
J Cell Sci. 2000 Jan;113 ( Pt 1):71-80.
165. Samandari T, Kotloff KL, Losonsky GA, Picking WD, Sansonetti PJ, Levine MM, Sztein MB.
Production of IFN-gamma and IL-10 to Shigella invasins by mononuclear cells from volunteers orally inoculated with a Shiga toxin-deleted Shigella dysenteriae type 1 strain.
J Immunol. 2000 Feb 15;164(4):2221-32.
166. Skoudy A, Mounier J, Aruffo A, Ohayon H, Gounon P, Sansonetti P, Tran Van Nhieu G
CD44 binds to the Shigella IpaB protein and participates in bacterial invasion of epithelial cells.
Cell Microbiol. 2000 Feb;2(1):19-33.
167. Francois M, Le Cabec V, Dupont MA, Sansonetti PJ, Maridonneau-Parini I.
Induction of necrosis in human neutrophils by Shigella flexneri requires type III secretion, IpaB and IpaC invasins, and actin polymerization.
Infect Immun. 2000 Mar;68(3):1289-96.
168. Wenneras C, Ave P, Huerre M, Arondel J, Ulevitch RJ, Mathison JC, Sansonetti P
Blockade of CD14 increases Shigella-mediated invasion and tissue destruction.
J Immunol. 2000 Mar 15;164(6):3214-21.
169. Rathman M, Jouirhi N, Allaoui A, Sansonetti P, Parsot C, Tran Van Nhieu G.
The development of a FACS-based strategy for the isolation of Shigella flexneri mutants that are deficient in intercellular spread.
Mol Microbiol. 2000 Mar;35(5):974-90.
170. Sansonetti PJ
Microbial pathogenesis: new paths into a new millennium.
Trends Microbiol. 2000 May;8(5):196-7.
171. Sansonetti PJ, Phalipon A, Arondel J, Thirumalai K, Banerjee S, Akira S, Takeda K, Zychlinsky A
Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation.
Immunity. 2000 May;12(5):581-90.
172. Tavares P, Sansonetti P, Guillen N
Cell polarization and adhesion in a motile pathogenic protozoan: role and fate of the Entamoeba histolytica Gal/GalNAc lectin.
Microbes Infect. 2000 May;2(6):643-9.
173. Bourdet-Sicard R, Egile C, Sansonetti PJ, Tran Van Nhieu G
Diversion of cytoskeletal processes by Shigella during invasion of epithelial cells.
Microbes Infect. 2000 Jun;2(7):813-9.
174. Tran Van Nhieu G, Bourdet-Sicard R, Dumenil G, Blocker A, Sansonetti PJ
Bacterial signals and cell responses during Shigella entry into epithelial cells.
Cell Microbiol. 2000 Jun;2(3):187-93.
175. Carlier MF, Nioche P, Broutin-L'Hermite I, Boujemaa R, Le Clainche C, Egile C, Garbay C, Ducruix A, Sansonetti P, Pantaloni D
GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex.
J Biol Chem. 2000 Jul 21;275(29):21946-52.
176. Niebuhr K, Sansonetti PJ
Invasion of epithelial cells by bacterial pathogens the paradigm of Shigella.
Subcell Biochem. 2000;33:251-87.
177. Philpott DJ, Edgeworth JD, Sansonetti PJ
The pathogenesis of Shigella flexneri infection: lessons from in vitro and in vivo studies.
Philos Trans R Soc Lond B Biol Sci. 2000 May 29;355(1397):575-86. Review.
178. Philpott DJ, Yamaoka S, Israel A, Sansonetti PJ
Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells.
J Immunol. 2000 Jul 15;165(2):903-14.
179. Labruyere E, Galy V, Sansonetti P, Guillen N
Distribution of a potential p21-activated serine/threonine kinase (PAK) in Entamoeba histolytica.
Arch Med Res. 2000 Jul-Aug;31(4 Suppl):S128-30.
180. Tavares P, Sansonetti P, Guillen N
The interplay between receptor capping and cytoskeleton remodeling in Entamoeba histolytica.
Arch Med Res. 2000 Jul-Aug;31(4 Suppl):S140-2.
181. De Geyter C, Wattiez R, Sansonetti P, Falmagne P, Ruysschaert JM, Parsot C, Cabiaux V
Characterization of the interaction of IpaB and IpaD, proteins required for entry of Shigella flexneri into epithelial cells, with a lipid membrane.
Eur J Biochem. 2000 Sep;267(18):5769-76.
182. Rathman M, de Lanerolle P, Ohayon H, Gounon P, Sansonetti P
Myosin light chain kinase plays an essential role in S. flexneri dissemination.
J Cell Sci. 2000 Oct;113 Pt 19:3375-86.
183. Niebuhr K, Jouihri N, Allaoui A, Gounon P, Sansonetti PJ, Parsot C
IpgD, a protein secreted by the type III secretion machinery of Shigella flexneri, is chaperoned by IpgE and implicated in entry focus formation.
Mol Microbiol. 2000 Oct;38(1):8-19.
184. Buchrieser C, Glaser P, Rusniok C, Nedjari H, D'Hauteville H, Kunst F, Sansonetti P, Parsot C
The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri.
Mol Microbiol. 2000 Nov;38(4):760-71.
185. Mulard, L.A. , Costachel, C., Sansonetti, P. J.
Synthesis of the methyl glycosides of a di- and two trisaccharide fragments specific for the Shigella flexneri serotype 2a O-antigen.
J. Carbohydr. Chem. 2000, 19 (7) :849-877.
186. Costachel, C., Sansonetti, P.J., Mulard, L.A.
Linear synthesis of the methyl glycosides of tetra- and pentasaccharide fragments specific for the Shigella flexneri serotype 2a O-antigen.
J. Carbohydr. Chem. 2000, 19 (9) :1131-1150.
187. Sansonetti PJ
Rupture, invasion and inflammatory destruction of the intestinal barrier by Shigella, making sense of prokaryote-eukaryote cross-talks.
FEMS Microbiol Rev. 2001 Jan;25(1):3-14. Review. No abstract available.
188. Bernardini ML, Arondel J, Martini I, Aidara A, Sansonetti PJ
Parameters underlying successful protection with live attenuated mutants in experimental shigellosis.
Infect Immun. 2001 Feb;69(2):1072-83.
189. Blocker A, Jouihri N, Larquet E, Gounon P, Ebel F, Parsot C, Sansonetti P, Allaoui A
Structure and composition of the Shigella flexneri "needle complex", a part of its type III secreton.
Mol Microbiol. 2001 Feb;39(3):652-63.
190. Subtil A, Parsot C, Dautry-Varsat A
Secretion of predicted Inc proteins of Chlamydia pneumoniae by a heterologous type III machinery.
Mol Microbiol. 2001 Feb;39(3):792-800.
191. Sansonetti PJ
Microbes and microbial toxins: paradigms for microbial-mucosal interactions III. Shigellosis: from symptoms to molecular pathogenesis.
Am J Physiol Gastrointest Liver Physiol. 2001 Mar;280(3):G319-23.
192. Girardin SE, Tournebize R, Mavris M, Page AL, Li X, Stark GR, Bertin J, DiStefano PS, Yaniv M, Sansonetti PJ, Philpott DJ
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.
EMBO Rep. 2001 Aug;2(8):736-42.
193. Philpott DJ, Girardin SE, Sansonetti PJ
Innate immune responses of epithelial cells following infection with bacterial pathogens.
Curr Opin Immunol. 2001 Aug;13(4):410-6.
194. Rasolofo-Razanamparany V, Cassel-Beraud AM, Roux J, Sansonetti PJ, Phalipon A
Predominance of serotype-specific mucosal antibody response in Shigella flexneri-infected humans living in an area of endemicity.
Infect Immun. 2001 Sep;69(9):5230-4.

195. Page AL, Fromont-Racine M, Sansonetti P, Legrain P, Parsot C
Characterization of the interaction partners of secreted proteins and chaperones of Shigella flexneri.
Mol Microbiol. 2001 Nov;42(4):1133-45.

196. Sansonetti P
Phagocytosis of bacterial pathogens: implications in the host response.
Semin Immunol. 2001 Dec;13(6):381-90. Review.
197. Wenneras C, Ave P, Huerre M, Arondel J, Ulevitch R, Mathison J, Sansonetti P
Blockade of CD14 aggravates experimental shigellosis.
J Endotoxin Res. 2001;7(6):442-6.
198. Page AL, Sansonetti P, Parsot C
Spa15 of Shigella flexneri, a third type of chaperone in the type III secretion pathway.
Mol Microbiol. 2002 Mar;43(6):1533-42.
199. Mavris M, Page AL, Tournebize R, Demers B, Sansonetti P, Parsot C
Regulation of transcription by the activity of the Shigella flexneri type III secretion apparatus.
Mol Microbiol. 2002 Mar;43(6):1543-53.
200. Reed KA, Hobert ME, Kolenda CE, Sands KA, Rathman M, O'Connor M, Lyons S, Gewirtz AT, Sansonetti PJ, Madara JL
The Salmonella typhimurium flagellar basal body protein FliE is required for flagellin production and to induce a proinflammatory response in epithelial cells.
J Biol Chem. 2002 Apr 12;277(15):13346-53.
201. Girardin SE, Sansonetti PJ, Philpott DJ
Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies.
Trends Microbiol. 2002 Apr;10(4):193-9.
202. Sansonetti P
Host-pathogen interactions: the seduction of molecular cross talk.
Gut. 2002 May;50 Suppl 3:III2-8.
203. Edgeworth JD, Spencer J, Phalipon A, Griffin GE, Sansonetti PJ
Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells.
Eur J Immunol. 2002 May;32(5):1464-71.
204. D'Hauteville H, Khan S, Maskell DJ, Kussak A, Weintraub A, Mathison J, Ulevitch RJ, Wuscher N, Parsot C, Sansonetti PJ
Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium.
J Immunol. 2002 May 15;168(10):5240-51.
205. Raqib R, Ekberg C, Sharkar P, Bardhan PK, Zychlinsky A, Sansonetti PJ, Andersson J
Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2.
Infect Immun. 2002 Jun;70(6):3199-207.
206. Fullner KJ, Boucher JC, Hanes MA, Haines GK 3rd, Meehan BM, Walchle C, Sansonetti PJ, Mekalanos JJ
The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model.
J Exp Med. 2002 Jun 3;195(11):1455-62.
207. Hathaway LJ, Griffin GE, Sansonetti PJ, Edgeworth JD
Human monocytes kill Shigella flexneri but then die by apoptosis associated with suppression of proinflammatory cytokine production.
Infect Immun. 2002 Jul;70(7):3833-42.
208. Phalipon A, Cardona A, Kraehenbuhl JP, Edelman L, Sansonetti PJ, Corthesy B
Secretory component: a new role in secretory IgA-mediated immune exclusion in vivo.
Immunity. 2002 Jul;17(1):107-15.
209. Lafont F, Tran Van Nhieu G, Hanada K, Sansonetti P, van der Goot FG
Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction.
EMBO J. 2002 Sep 2;21(17):4449-57.
210. Nutten S, Sansonetti P, Huet G, Bourdon-Bisiaux C, Meresse B, Colombel J, Desreumaux P
Epithelial inflammation response induced by Shigella flexneri depends on mucin gene expression.
Microbes Infect. 2002 Sep;4(11):1121.
211. Niebuhr K, Giuriato S, Pedron T, Philpott DJ, Gaits F, Sable J, Sheetz MP, Parsot C, Sansonetti PJ, Payrastre B
Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology.
EMBO J. 2002 Oct 1;21(19):5069-5078.
212. Page AL, Parsot C
Chaperones of the type III secretion pathway: jacks of all trades.
Mol Microbiol. 2002 Oct;46(1):1-11.