Welcome to the web-pages of the recently created unit for Integrated Mycobacterial Pathogenomics (PMI), The research undertaken in our unit is centered on genomics and pathogenicity of mycobacteria, to uncover novel features of mycobacterial pathogens in relation to evolution and the interaction with the host. While most mycobacteria are harmless saprophytes, a few species have very efficiently adapted to a pathogenic lifestyle and constitute some of most important human pathogens. There are Mycobacterium tuberculosis, the causative agent of human tuberculosis, Mycobacterium leprae , the cause of leprosy and the emerging pathogen Mycobacterium ulcerans, which causes Buruli ulcer, a most serious skin disease mainly prevalent in West Africa. Several aspects of our research are based on the pioneering studies on mycobacterial genomics that have been undertaken in recent years at the Institut Pasteur in the Unit for Molecular Bacterial Genetics (Director Pr. Stewart Cole, now at EPFL) with the strong implication of the team members of PMI. To obtain further information on various subjects of mycobacterial research, please click below: Mycobacteria: Genomics,  TB drug discovery , BACs,   Deletions,   Evolution , Duplications,   Resistance   and Interactive gene/protein-search tool - M. tuberculosis : TubercuList, Interactive gene/protein-search tool - M. bovis : BoviList, Interactive gene/protein-search tool - M. bovis BCG : BCGList, Interactive gene/protein-search tool - M. marinum : MarinoList Interactive gene/protein-search tool - M. ulcerans: BuruList. Interactive gene/protein-search tool - M. leprae: Leproma. Recent publications of members of the Unit: postal address of the Unit: Institut Pasteur, Pathogenomique Mycobacterienne Integree, 25 Rue du Dr. Roux, 75724 PARIS Cedex 15, France, Tel.: +33-1-4568 8446 Office, Tel.: +33-1-4568 8449 Lab, Fax.: +33-1-4061 3583, mailserver Head of the Unit: Roland BROSCH , IP, (Sciencewatch-interview) Office Anne-Marie FARGUES, IP, Permanent Staff Members Caroline DEMANGEL, IP, Wafa FRIGUI, IP, Nadine HONORE , IP, Post-Docs, Students, and Temporary Staff Members Alessandro CASCIOFERRO Laure GUENIN-MACE Fabien LE CHEVALIER Mickael ORGEUR Alexandre PAWLIK Roxane SIMEONE Romain VEYRON CHURLET People who recently left the Unit: Priscille BRODIN Laxmee CALEECHURN Emmanuel CHAPLAIS Marion LECLERC Cecile PARMENTIER Erica PORTER Brigitte SAINT-JOANIS Please address questions and comments to Roland BROSCH WebCounter Last update: November, 24, 2011 DISCLAIMER The information contained in the unit's webpages is provided in good faith, but no warranty, nor any legal liability or responsibility for any purpose for which the data are used, is given.