Publications

2014


Decourty, Laurence; Doyen, Antonia; Malabat, Christophe; Frachon, Emmanuel; Rispal, Delphine; Séraphin, Bertrand; Feuerbach, Frank; Jacquier, Alain; Saveanu, Cosmin, (2014), Long open reading frame transcripts escape nonsense-mediated mRNA decay in yeast, Cell Rep, 6(4), 593-598


Daum, Bertram; Quax, Tessa E. F.; Sachse, Martin; Mills, Deryck J.; Reimann, Julia; Yildiz, Özkan; Häder, Sabine; Saveanu, Cosmin; Forterre, Patrick; Albers, Sonja-Verena; Kühlbrandt, Werner; Prangishvili, David, (2014), Self-assembly of the general membrane-remodeling protein PVAP into sevenfold virus-associated pyramids, PNAS, (), -

2013


Zeidler, Ute; Bougnoux, Marie-Elisabeth; Lupan, Alexandru; Helynck, Olivier; Doyen, Antonia; Garcia, Zacarias; Sertour, Natacha; Clavaud, Cécile; Munier-Lehmann, Hélène; Saveanu, Cosmin; d'Enfert, Christophe, (2013), Synergy of the antibiotic colistin with echinocandin antifungals in Candida species, J. Antimicrob. Chemother., 68(6), 1285-1296


Defenouillère, Quentin; Yao, Yanhua; Mouaikel, John; Namane, Abdelkader; Galopier, Aurélie; Decourty, Laurence; Doyen, Antonia; Malabat, Christophe; Saveanu, Cosmin; Jacquier, Alain; Fromont-Racine, Micheline, (2013), Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products, Proc. Natl. Acad. Sci. U.S.A., 110(13), 5046-5051


Babiano, Reyes; Badis, Gwenael; Saveanu, Cosmin; Namane, Abdelkader; Doyen, Antonia; Díaz-Quintana, Antonio; Jacquier, Alain; Fromont-Racine, Micheline; de la Cruz, Jesús, (2013), Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles, Nucleic Acids Res., 41(20), 9461-9470

2012


Gudipati, Rajani Kanth; Xu, Zhenyu; Lebreton, Alice; Séraphin, Bertrand; Steinmetz, Lars M; Jacquier, Alain; Libri, Domenico, (2012), Extensive degradation of RNA precursors by the exosome in wild-type cells, Mol. Cell, 48(3), 409-421


Peyroche, Gérald; Saveanu, Cosmin; Dauplais, Marc; Lazard, Myriam; Beuneu, François; Decourty, Laurence; Malabat, Christophe; Jacquier, Alain; Blanquet, Sylvain; Plateau, Pierre, (2012), Sodium selenide toxicity is mediated by O2-dependent DNA breaks, PLoS ONE, 7(5), -


Gudipati, Rajani Kanth; Neil, Helen; Feuerbach, Frank; Malabat, Christophe; Jacquier, Alain, (2012), The yeast RPL9B gene is regulated by modulation between two modes of transcription termination, EMBO J., 31(10), 2427-2437

2011


Neil, Helen; Jacquier, Alain, (2011), Enrichment of unstable non-coding RNAs and their genome-wide identification, Methods Mol. Biol., 759(), 87-106


Daugeron, Marie-Claire; Lenstra, Tineke L; Frizzarin, Martina; El Yacoubi, Basma; Liu, Xipeng; Baudin-Baillieu, Agnès; Lijnzaad, Philip; Decourty, Laurence; Saveanu, Cosmin; Jacquier, Alain; Holstege, Frank C P; de Crécy-Lagard, Valérie; van Tilbeurgh, Herman; Libri, Domenico, (2011), Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs, Nucleic Acids Res., 39(14), 6148-6160

2010


Yao, Yanhua; Demoinet, Emilie; Saveanu, Cosmin; Lenormand, Pascal; Jacquier, Alain; Fromont-Racine, Micheline, (2010), Ecm1 is a new pre-ribosomal factor involved in pre-60S particle export, RNA, 16(5), 1007-1017

2009


Jacquier, Alain, (2009), The complex eukaryotic transcriptome: unexpected pervasive transcription and novel small RNAs, Nat. Rev. Genet., 10(12), 833-844


Grainger, Richard J; Barrass, J David; Jacquier, Alain; Rain, Jean-Christophe; Beggs, Jean D, (2009), Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome, RNA, 15(12), 2161-2173


Kafasla, Panagiota; Barrass, J David; Thompson, Elizabeth; Fromont-Racine, Micheline; Jacquier, Alain; Beggs, Jean D; Lewis, Joe, (2009), Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events, RNA Biol, 6(5), 563-574


Holbein, Sandra; Wengi, Agnieszka; Decourty, Laurence; Freimoser, Florian M; Jacquier, Alain; Dichtl, Bernhard, (2009), Cordycepin interferes with 3' end formation in yeast independently of its potential to terminate RNA chain elongation, RNA, 15(5), 837-849


Neil, Helen; Malabat, Christophe; d'Aubenton-Carafa, Yves; Xu, Zhenyu; Steinmetz, Lars M; Jacquier, Alain, (2009), Widespread bidirectional promoters are the major source of cryptic transcripts in yeast, Nature, 457(7232), 1038-1042

2008


Thiebaut, Marilyne; Colin, Jessie; Neil, Helen; Jacquier, Alain; Séraphin, Bertrand; Lacroute, François; Libri, Domenico, (2008), Futile cycle of transcription initiation and termination modulates the response to nucleotide shortage in S. cerevisiae, Mol. Cell, 31(5), 671-682


Lebreton, Alice; Rousselle, Jean-Claude; Lenormand, Pascal; Namane, Abdelkader; Jacquier, Alain; Fromont-Racine, Micheline; Saveanu, Cosmin, (2008), 60S ribosomal subunit assembly dynamics defined by semi-quantitative mass spectrometry of purified complexes, Nucleic Acids Res., 36(15), 4988-4999


Milligan, Laura; Decourty, Laurence; Saveanu, Cosmin; Rappsilber, Juri; Ceulemans, Hugo; Jacquier, Alain; Tollervey, David, (2008), A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts, Mol. Cell. Biol., 28(17), 5446-5457


Decourty, Laurence; Saveanu, Cosmin; Zemam, Kenza; Hantraye, Florence; Frachon, Emmanuel; Rousselle, Jean-Claude; Fromont-Racine, Micheline; Jacquier, Alain, (2008), Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles, Proc. Natl. Acad. Sci. U.S.A., 105(15), 5821-5826

2007


Berger, Axel B; Decourty, Laurence; Badis, Gwenaël; Nehrbass, Ulf; Jacquier, Alain; Gadal, Olivier, (2007), Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription, Mol. Cell. Biol., 27(22), 8015-8026


Demoinet, Emilie; Jacquier, Alain; Lutfalla, Georges; Fromont-Racine, Micheline, (2007), The Hsp40 chaperone Jjj1 is required for the nucleo-cytoplasmic recycling of preribosomal factors in Saccharomyces cerevisiae, RNA, 13(9), 1570-1581


Pertschy, Brigitte; Saveanu, Cosmin; Zisser, Gertrude; Lebreton, Alice; Tengg, Martin; Jacquier, Alain; Liebminger, Eva; Nobis, Berthold; Kappel, Lisa; van der Klei, Ida; Högenauer, Gregor; Fromont-Racine, Micheline; Bergler, Helmut, (2007), Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1, Mol. Cell. Biol., 27(19), 6581-6592


Boisset, Sandrine; Geissmann, Thomas; Huntzinger, Eric; Fechter, Pierre; Bendridi, Nadia; Possedko, Maria; Chevalier, Clément; Helfer, Anne Catherine; Benito, Yvonne; Jacquier, Alain; Gaspin, Christine; Vandenesch, François; Romby, Pascale, (2007), Staphylococcus aureus RNAIII coordinately represses the synthesis of virulence factors and the transcription regulator Rot by an antisense mechanism, Genes Dev., 21(11), 1353-1366


Garcia, Olivier; Saveanu, Cosmin; Cline, Melissa; Fromont-Racine, Micheline; Jacquier, Alain; Schwikowski, Benno; Aittokallio, Tero, (2007), GOlorize: a Cytoscape plug-in for network visualization with Gene Ontology-based layout and coloring, Bioinformatics, 23(3), 394-396


Saveanu, Cosmin; Rousselle, Jean-Claude; Lenormand, Pascal; Namane, Abdelkader; Jacquier, Alain; Fromont-Racine, Micheline, (2007), The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors, Mol. Cell. Biol., 27(8), 2897-2909

2006


Lebreton, Alice; Saveanu, Cosmin; Decourty, Laurence; Jacquier, Alain; Fromont-Racine, Micheline, (2006), Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs, J. Biol. Chem., 281(37), 27099-27108


Lebreton, Alice; Saveanu, Cosmin; Decourty, Laurence; Rain, Jean-Christophe; Jacquier, Alain; Fromont-Racine, Micheline, (2006), A functional network involved in the recycling of nucleocytoplasmic pre-60S factors, J. Cell Biol., 173(3), 349-360

2005


Lebaron, Simon; Froment, Carine; Fromont-Racine, Micheline; Rain, Jean-Christophe; Monsarrat, Bernard; Caizergues-Ferrer, Michèle; Henry, Yves, (2005), The splicing ATPase prp43p is a component of multiple preribosomal particles, Mol. Cell. Biol., 25(21), 9269-9282


Wyers, Françoise; Rougemaille, Mathieu; Badis, Gwenaël; Rousselle, Jean-Claude; Dufour, Marie-Elisabeth; Boulay, Jocelyne; Régnault, Béatrice; Devaux, Frédéric; Namane, Abdelkader; Séraphin, Bertrand; Libri, Domenico; Jacquier, Alain, (2005), Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase, Cell, 121(5), 725-737


LaCava, John; Houseley, Jonathan; Saveanu, Cosmin; Petfalski, Elisabeth; Thompson, Elizabeth; Jacquier, Alain; Tollervey, David, (2005), RNA degradation by the exosome is promoted by a nuclear polyadenylation complex, Cell, 121(5), 713-724


Torchet, Claire; Badis, Gwenaël; Devaux, Frédéric; Costanzo, Ginny; Werner, Michel; Jacquier, Alain, (2005), The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae, RNA, 11(6), 928-938


Huntzinger, Eric; Boisset, Sandrine; Saveanu, Cosmin; Benito, Yvonne; Geissmann, Thomas; Namane, Abdelkader; Lina, Gérard; Etienne, Jerome; Ehresmann, Bernard; Ehresmann, Chantal; Jacquier, Alain; Vandenesch, François; Romby, Pascale, (2005), Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression, EMBO J., 24(4), 824-835

2004


Badis, Gwenael; Saveanu, Cosmin; Fromont-Racine, Micheline; Jacquier, Alain, (2004), Targeted mRNA degradation by deadenylation-independent decapping, Mol. Cell, 15(1), 5-15


Léger-Silvestre, Isabelle; Milkereit, Philipp; Ferreira-Cerca, Sébastien; Saveanu, Cosmin; Rousselle, Jean-Claude; Choesmel, Valérie; Guinefoleau, Cécile; Gas, Nicole; Gleizes, Pierre-Emmanuel, (2004), The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast, EMBO J., 23(12), 2336-2347


Donnini, Martino; Lapucci, Andrea; Papucci, Laura; Witort, Ewa; Jacquier, Alain; Brewer, Gary; Nicolin, Angelo; Capaccioli, Sergio; Schiavone, Nicola, (2004), Identification of TINO: a new evolutionarily conserved BCL-2 AU-rich element RNA-binding protein, J. Biol. Chem., 279(19), 20154-20166


Galy, Vincent; Gadal, Olivier; Fromont-Racine, Micheline; Romano, Alper; Jacquier, Alain; Nehrbass, Ulf, (2004), Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1, Cell, 116(1), 63-73

2003


Fromont-Racine, Micheline; Senger, Bruno; Saveanu, Cosmin; Fasiolo, Franco, (2003), Ribosome assembly in eukaryotes, Gene, 313(), 17-42


Badis, Gwenael; Fromont-Racine, Micheline; Jacquier, Alain, (2003), A snoRNA that guides the two most conserved pseudouridine modifications within rRNA confers a growth advantage in yeast, RNA, 9(7), 771-779


Saveanu, Cosmin; Namane, Abdelkader; Gleizes, Pierre-Emmanuel; Lebreton, Alice; Rousselle, Jean-Claude; Noaillac-Depeyre, Jacqueline; Gas, Nicole; Jacquier, Alain; Fromont-Racine, Micheline, (2003), Sequential protein association with nascent 60S ribosomal particles, Mol. Cell. Biol., 23(13), 4449-4460


Braunwarth, Andreas; Fromont-Racine, Micheline; Legrain, Pierre; Bischoff, F Ralf; Gerstberger, Thomas; Hurt, Ed; Kunzler, Markus, (2003), Identification and characterization of a novel RanGTP-binding protein in the yeast Saccharomyces cerevisiae, J. Biol. Chem., 278(17), 15397-15405

2002


Cost, Gregory J; Feng, Qinghua; Jacquier, Alain; Boeke, Jef D, (2002), Human L1 element target-primed reverse transcription in vitro, EMBO J., 21(21), 5899-5910


Fromont-Racine, Micheline; Rain, Jean-Christophe; Legrain, Pierre, (2002), Building protein-protein networks by two-hybrid mating strategy, Meth. Enzymol., 350(), 513-524


Le Masson, Ivan; Saveanu, Cosmin; Chevalier, Anne; Namane, Abdelkader; Gobin, Renée; Fromont-Racine, Micheline; Jacquier, Alain; Mann, Carl, (2002), Spc24 interacts with Mps2 and is required for chromosome segregation, but is not implicated in spindle pole body duplication, Mol. Microbiol., 43(6), 1431-1443


Feuerbach, Frank; Galy, Vincent; Trelles-Sticken, Edgar; Fromont-Racine, Micheline; Jacquier, Alain; Gilson, Eric; Olivo-Marin, Jean-Christophe; Scherthan, Harry; Nehrbass, Ulf, (2002), Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast, Nat. Cell Biol., 4(3), 214-221

2001


Page, A L; Fromont-Racine, M; Sansonetti, P; Legrain, P; Parsot, C, (2001), Characterization of the interaction partners of secreted proteins and chaperones of Shigella flexneri, Mol. Microbiol., 42(4), 1133-1145


Schaper, S; Fromont-Racine, M; Linder, P; de la Cruz, J; Namane, A; Yaniv, M, (2001), A yeast homolog of chromatin assembly factor 1 is involved in early ribosome assembly, Curr. Biol., 11(23), 1885-1890


Saveanu, C; Bienvenu, D; Namane, A; Gleizes, P E; Gas, N; Jacquier, A; Fromont-Racine, M, (2001), Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps, EMBO J., 20(22), 6475-6484


Belgareh, N; Rabut, G; Baï, S W; van Overbeek, M; Beaudouin, J; Daigle, N; Zatsepina, O V; Pasteau, F; Labas, V; Fromont-Racine, M; Ellenberg, J; Doye, V, (2001), An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells, J. Cell Biol., 154(6), 1147-1160


Saveanu, C; Fromont-Racine, M; Harington, A; Ricard, F; Namane, A; Jacquier, A, (2001), Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues, J. Biol. Chem., 276(19), 15861-15867

2000


Fromont-Racine, M; Mayes, A E; Brunet-Simon, A; Rain, J C; Colley, A; Dix, I; Decourty, L; Joly, N; Ricard, F; Beggs, J D; Legrain, P, (2000), Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins, Yeast, 17(2), 95-110


Chanfreau, G; Buckle, M; Jacquier, A, (2000), Recognition of a conserved class of RNA tetraloops by Saccharomyces cerevisiae RNase III, Proc. Natl. Acad. Sci. U.S.A., 97(7), 3142-3147

1999


Chanfreau, G; Gouyette, C; Schwer, B; Jacquier, A, (1999), Trans-complementation of the second step of pre-mRNA splicing by exogenous 5' exons, RNA, 5(7), 876-882


Dème, E; Nolte, A; Jacquier, A, (1999), Unexpected metal ion requirements specific for catalysis of the branching reaction in a group II intron, Biochemistry, 38(10), 3157-3167

1998


Chanfreau, G; Legrain, P; Jacquier, A, (1998), Yeast RNase III as a key processing enzyme in small nucleolar RNAs metabolism, J. Mol. Biol., 284(4), 975-988


Chanfreau, G; Rotondo, G; Legrain, P; Jacquier, A, (1998), Processing of a dicistronic small nucleolar RNA precursor by the RNA endonuclease Rnt1, EMBO J., 17(13), 3726-3737


Nolte, A; Chanfreau, G; Jacquier, A, (1998), Influence of substrate structure on in vitro ribozyme activity of a group II intron, RNA, 4(6), 694-708


Cho, R J; Fromont-Racine, M; Wodicka, L; Feierbach, B; Stearns, T; Legrain, P; Lockhart, D J; Davis, R W, (1998), Parallel analysis of genetic selections using whole genome oligonucleotide arrays, Proc. Natl. Acad. Sci. U.S.A., 95(7), 3752-3757

1997


Fromont-Racine, M; Rain, J C; Legrain, P, (1997), Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens, Nat. Genet., 16(3), 277-282


Couttet, P; Fromont-Racine, M; Steel, D; Pictet, R; Grange, T, (1997), Messenger RNA deadenylylation precedes decapping in mammalian cells, Proc. Natl. Acad. Sci. U.S.A., 94(11), 5628-5633


Jestin, J L; Dème, E; Jacquier, A, (1997), Identification of structural elements critical for inter-domain interactions in a group II self-splicing intron, EMBO J., 16(10), 2945-2954


Costa, M; Déme, E; Jacquier, A; Michel, F, (1997), Multiple tertiary interactions involving domain II of group II self-splicing introns, J. Mol. Biol., 267(3), 520-536