Contacts:
jmghigo[@]pasteur.fr
Tel + (33) 1 40 61 34 18
Fax+ (33) 1 45 68 80 07
Contacts:
jmghigo@pasteur.fr
Tel + (33) 1 40 61 39 17
Fax+ (33) 1 40 61 39 70
Contacts:
jmghigo@pasteur.fr
Tel + (33) 1 40 61 39 17
Fax+ (33) 1 40 61 39 70

Contacts:
jmghigo@pasteur.fr
Tel + (33) 1 40 61 39 17
Fax+ (33) 1 40 61 39 70

 
 
 (Underlined names = external collaborators)

 • A. Jacquot ; C. Sakamoto ; A. Razafitianamaharavo ; C. Caillet J. Merlin ; A. Fahs ; J.M. Ghigo ; J.F.L. Duval ;  C. Beloin and G. Francius.(2014) Dynamics and pH-dependence of Ag43 adhesins self-association probed by Atomic Force Spectroscopy. Nanoscale in press

• Chalabaev, S. Chauhan, A.; Novikov, A.; Iyer, P.; Szczesny, M.; Beloin, C.; Caroff, M.; and J.M. Ghigo. (2014) Biofilms formed by Gram-negative bacteria undergo lipid A palmitoylation enhancing in vivo survival. mBio Aug 19;5(4). pii: e01116-14

• Lebeaux, D.; Ghigo, J.M. and C. Beloin. (2014) Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance towards antibiotics Microbiology and Molecular Biology Reviews in press (REVIEW)

Geng, J. ; Beloin, C. ; Ghigo, J.M. and N. Henry. Bacteria hold their breath upon surface contact as shown in a strain of Escherichia coli, using dispersed surfaces and flow cytometry analysis.PLoS One Jul 23;9(7):e102049

• Lebeaux, D.; Chauhan A.; Létoffé, S.; Fischer, F.; De Reuse, H.; Beloin, C. and J.M. Ghigo (2014)   pH-mediated potentiation of aminoglycosides kills bacterial persisters and eradicates in vivo biofilms The Journal of Infectious Diseases May 15. pii: jiu286.

•  Barraud, N.; Moscoso, J.A.; J.M. Ghigo and A. Filloux (2013) Methods for studying biofilm dispersal in Pseudomonas aeruginosa  Methods in Molecular Biology 1149:643-51. (METHOD)

P. Bielecki, U. Muthukumarasamy, D. Eckweiler, A. Bielecka, S. Pohl, A. Schanz, U. Niemeyer, T. Oumeraci, N. von Neuhoff, J.M Ghigo and S. Haussler. mRNA profiling of uropathogenic Escherichia coli from diverse phylo-groups reveals common and group specific gene expression profiles during the course of human urinary tract infections. mBio Aug 5;5(4):e01075-14.

•  Chauhan, A.; Bernardin, A.;  Mussard, W.; Kriegel, I.; Esteve, M.; Ghigo, J.M.; Beloin*, C.; and V. Semetey*. (2014) Preventing biofilm formation and associated occlusion by biomimetic glycocalyx-like polymer in central venous catheters. The Journal of Infectious Diseases May 1. [Epub ahead of print]

•  Zaïri, A. ; Ferrières, L.; Latour-Lambert, P. ; Beloin, C. ; Tangy, F. ; Ghigo, J.M. and K. Hani(2014) In vitro activity of Dermaseptins K4S4 and K4K20S4 against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa planktonic growth and biofilm formation. Antimicrobial Agents Chemotherapy Apr;58(4):2221-8

Jacquot A., Sakamoto C., Razafitianamaharavo. A., Merlin J., Fahs A., Ghigo J.M., Beloin C.#, Duval J.F.L.# and G. Francius. (2014) Dynamic modulation of fimbrial extension and FimH-Mannose binding force on live bacteria under pH changes: a molecular AFM analysis. J of Biomedicine & NanotechnologyIn press.   equivalent contribution

Zrelli, K.; Galy, O.; Latour-Lambert, P.; Kirwan, L.; Ghigo, J.M.; Beloin, C. and N. Henry (2014) Bacterial biofilm mechanical properties persist upon antibiotic treatment and survive cell death. New Journal of Physics  Sep 19;103(6):1400-8

• Balloy, V.; Deveaux, A.; Lebeaux, D.; Tabary, O.; Le Rouzic, P. ; Ghigo, J.M. ; Boëlle, P.Y., Clement, A. Chignard, M.; Corvol, H. ; Burnet, M. and  L. Guillot. (2014). Azithromycin Analog CSY0073 Attenuates Lung Inflammation induced by Lipopolysaccharide Challenge British Journal of Pharmacology Apr;171(7):1783-94

• Rendueles, O.; Beloin, C.; Latour-Lambert, P. and Ghigo J.M.. (2014). A new biofilm-associated colicin targeting E. coli biofilm bacteria The ISME Journal.Jun;8(6):1275-88

• Létoffé, S.; Audrain, B.; Bernier, S. ; Delepierre, M and Ghigo J.M.(2014)Aerial exposure to the bacterial volatile compound trimethylamine modifies antibiotic resistance of physically separated bacteria by raising medium pH. mBio Jan 7;5(1):e00944-13..

• Lebeaux, D.; Fernández-Hidalgo, N. ; Chauhan, A. ; Lee, S. ; Ghigo, J.M. Almirante, B.  and C.Beloin (2014). Management of totally implantable venous access port-related infections: challenges and perspectives in revision for The Lancet Infectious Diseases Feb;14(2):146-59.

Audrain, B.; Ferrières, L.; Zairi, A.; Soubigou G., Dobson, C. ;J.-Y. Coppée; Beloin, C. and J.M. Ghigo. (2013) CpxAR two-component system contributes to resistance against cationic antimicrobial peptides in E. coli. Appl. Environl Microbiol. Dec;79(24):7770-9. doi: 10.1128.

Siriwardena, A.; Pulukuri,K. K; Kandiyal,P.S.; Roy, S.; Bande, O.; Martin, F.A.; Ghigo J.M.; Beloin, C.; Ghosh, S. Ampapathi, S.S. and KK. Chakraborty (2013) Carbohydrate-modified foldamers as conformationally defined and biologically distinct glycopeptide mimics. Angewandte Chemie Int Ed Sep 23;52(39):10221-6

Chauhan* A.; Sakamoto*, S.; Ghigo J.M. and C. Beloin (2013) Did I pick the right colony? Phase variation pitfalls in the study of regulation of phase variable antigen 43 adhesin PLoS One Sep 5;8(9):e73568.* equal contribution

Travier, L., Rendueles, O.; Ferrières, L.; Herry, J.M. and J.M. Ghigo. (2013) Escherichia coli resistance to non-biocidal anti-biofilm polysaccharide is rare and mediated by multiple mutations leading to surface charge modifications. Antimicrobial Agents ChemotherapyAug;57(8):3960-8

Da Re S.; Valle, J.,  Charbonnel, N.; Beloin, C.; Latour-Lambert, P.; Faure, P.; Turlin, E.; Le Bouguenec C; Renauld –Mongénie, G; Forestier, C. and J.M. Ghigo. (2013) Identification of commensal Escherichia coli genes involved in biofilm resistance to pathogen colonization. PloS ONE. May 7;8(5):e61628.

• F.A.Martin* ; A.Barras*; O. Bande; J.M. Ghigo ; Boukherroub, R. ; C. Beloin ; A. Siriwardena, S. Szunerits. (2013) Glyconanodialond as type 1 fimbriae inhibitors to limit bacterial adhesion. Nanoscale. Feb 28;5(6):2307-16.* equal contribution

• Travier, L., Guadagnini, S.; Gouin, E.; Dufour, A.; Chenal-Francisque V.; Leclercq, A.; Cossart, Ghigo, J.M.; P., Disson, O. and Marc Lecuit.(2013) ActA promotes Listeria monocytogenes aggregation, intestinal colonization and transmission, independently of its role in virulence. PLoS Pathogens.Jan;9(1):e1003131.

• Bernier, S.; Lebeaux, D.; DeFrancesco, A Valomon, A.; Soubigou, G.; , Coppee, J.Y.; Ghigo, J.M. and C. Beloin (2013) Starvation associated with the SOS response mediate high and biofilm-specific tolerance to the fluoroquinolone ofloxacin PLoS Genetics Jan;9(1):e1003144.

• Chauhan A.; Lebeaux, D.; Ghigo J.M. and C. Beloin. (2012) Full and broad-spectrum eradication of catheter-associated in vivo biofilms using Gentamicin-EDTA antibiotic lock therapy. Submitted to Antimicrobial Agents Chemotherapy 56(12):6310-8.

Allsopp, L.P.; Beloin, C.; Totsika, M.;  Ghigo, J.M. and M.A. Schembri.(2012) Functional heterogeneity of the UpaH autotransporter protein from uropathogenic Escherichia coli. J. Bacteriol 194(21):5769-82.

Galy, O. ; Latour-Lambert, P. ; Zrelli, K. ; Ghigo, J.M.; Beloin, C. and N.Henry.(2012) Mapping of bacterial biofilm local mechanics using magnetic microparticles The Biophysical Journal19;103(6):1400-8.

Rendueles, O.; Ferrieres, L.; Fretaud, M.; Begaud, E.; Hebomel, P.; Levraud, J.P. and J.M. Ghigo. (2012) A new zebrafish model of oro-intestinal pathogen colonization reveals a key role for adhesion in protection by probiotic bacteria. PLoS Pathogens.Jul;8(7):e1002815..

• Rendueles, O; Kaplan, JB; Ghigo, J.M. (2012) Antibiofilm polysaccharides Minireview. Environmental Microbiology Feb;15(2):334-46..

Prigent-Combaret, C. ;Sanguin, H. ; Champier, L. ; Bertrand, C. ; Monnez, C. ;Colinon, C. ; Blaha, D. ; Ghigo, J.M. and B. Cournoyer (2012) The bacterial thiopurine methyltransferase tellurite resistance process is highly dependent upon aggregation properties and oxidative stress response Environmental Microbiology14(10):2645-60

• Lebeaux, D. et J.M. Ghigo. (2012) Infections associées aux biofilms : quelles perspectives thérapeutiques issues de la recherche fondamentale? (In french) Médecine/Sciences Aug-Sep;28(8-9):727-39

• Chauhan A.; Lebeaux, D.; Decante, B.;  Kriegel, I.; Escande, M.C.; Ghigo J.M. and C. Beloin. (2012) A rat model of long-term indwelling device reveals the importance of immune system in controlling biofilm establishment and related infections.PloS ONE. 2012;7(5):e37281

• Totsika, M.; Wells, T.J.; Beloin, C.;Valle, J ; Allsopp, L.P.; King, N.   Ghigo, J.M. and M.A. Schembri. (2012) Molecular characterisation of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli. Appl Environ Microbiol.78(7):2179-89.

• Rendueles, O. and J.M. Ghigo Multi-species biofilms: How to avoid unfriendly neighbors. (2012). FEMS Microbiology Reviews Epub ahaed of print

(• Allsopp, L.P. ; Beloin, C., Ulett, G.C. ;Valle, J ; Totsika, M. ; Sherlock, O., Ghigo, J.M. and M.A. Schembri. (2012) Molecular Characterisation of UpaB and UpaC - two new Autotransporter Proteins of Uropathogenic Escherichia coli CFT073. Infection and Immunity 80(1):321-32.

• Bernier, S. ; Létoffé, S. ; Delepierre, M and Ghigo J.M.. (2011) Biogenic ammonia modifies antibiotic resistance at a distance in physically separated bacteria. Molecular Microbiology 81:705-716.

Francius, G. ; Poliakov, P. ; Merlin, J. ; Abe, Y. ; Ghigo, J.M. ; Merlin, C. ; Beloin, C. and J. Duval.(2011) Bacterial surface appendages strongly impact on nanomechanical and electrokinetic properties of Escherichia coli cells subjected to osmotic stress. PLoS ONE 6(5):e20066.

• Rendueles, O. ; Travier, L. ; Latour-Lambert, P. ; Fontaine, T. ; Magnus, J. ; Denamur, E.  and Ghigo J.M. (2011) Screening Escherichia coli species biodiversity reveals new biofilm-associated anti-adhesion polysaccharides. mBio 00043-11

• Korea, C. ; J. M. Ghigo and C. Beloin. (2011) The sweet connection: solving the riddle of multiple sugar-binding fimbrial adhesins in Escherichia coli Biessays . vol. 33 (4) pp. 300-11

Ferrieres, L., Hemery, G., Nham, T., Guerout, A. M., Mazel, D., Beloin, C. and Ghigo, J. M. (2010) Silent mischief: bacteriophage Mu insertions contaminate products of Escherichia coli random mutagenesis performed using suicidal transposon delivery plasmids mobilized by broad-host-range RP4 conjugative machinery  J Bacteriol.192:6418-27..

Korea C.; Badouraly R.; Prevost, M.C.; Ghigo J.M. and C.Beloin. (2010). E. coli K-12 possesses multiple cryptic but functional chaperone-usher fimbriae with distinct surface specificities. Environ Microbiol.12:1957-77.

• Cristina D. Ciornei, Alexey Novikov, Christophe Beloin, Catherine Fitting, Martine Caroff , Jean-Marc Ghigo, Jean-Marc Cavaillon And Minou Adib-Conquy.(2010).Biofilm-forming pseudomonas aeruginosa bacteria undergo lps structural modifications that induce enhanced inflammatory cytokine response in human monocytes. Innate Immun.16:288-301.

Le Quéré, B and J.M. Ghigo (2009). BcsQ is an essential component of the Escherichia coli cellulose biosynthesis apparatus that localizes at the bacterial cell pole.’ Molecular Microbiology 72(3), 724–740

Touchon, M. ; Hoede, C. ; Tenaillon, o. et al (2008) Organised genome dynamics in the Escherichia coli species: the path to adaptation. PLoS Genetics 5(1) e1000344

Beloin, C.; Houry, A;, Froment , M. ; Ghigo J.M. and N. Henry. A short time scale colloidal system reveals early bacterial adhesion dynamics and  adhesin-dependent behaviours. (2008) PLoS Biology July | Volume 6 | Issue 7 | e167.

 

 Collet, A. ; Cosette, P.; Beloin, C.; Ghigo, J.M.; Rihouey, C.; Lerouge, P.; Junter, G.A. And T. Jouenne.  Impact of rpoS deletion on the proteome of Escherichia coli grown as biofilm. (2008) Journal of Proteomic Research 7(11):4659-4669.

Beloin, C., Roux, A. and Ghigo, J. M. (2008) Escherichia coli biofilms  Curr Top Microbiol Immunol.322:249-89.

Valle, J., Mabbett, A. N., Ulett, G. C., Toledo-Arana, A., Wecker, K., Totsika, M., Schembri, M. A., Ghigo, J. M. and Beloin, C. ( 2008) UpaG, a new member of the trimeric autotransporter family of adhesins in uropathogenic Escherichia coli  J Bacteriol.190:4147-61.

Valle, J. : Da Re, S., Schmid. S. ; Skurnik, D. ; D’Ari, R. and Ghigo J.M. The amino-acid valine is secreted in continuous-flow bacterial biofilms. (2008) J. Bacteriol. 190(1):264-74.

Balestrino, D.; Ghigo J.M. ; Charbonnel, N. ; Haagensen, J.A.J. and C. Forestier. Individual and competitive screening of Klebsiella  pneumoniae factors involved in the establishment and maturation of in vitro biofilm. (2008) Environmental  Microbiology 10(3), 685–70141

•  Ulett, G.C. ; Valle, J. ; Beloin, C. ; Sherlock, O. ; Ghigo, J.M. and M. A. Schembri. (2007). Functional analysis of Antigen 43 in uropathogenic Escherichia coli reveals a role in long term persistence in the urinary tract. Infection and Immunity 75 3233-3244

 Da Re, S., Le Quere, Ghigo, J.M. and C. Beloin .(2007). Tight modulation of Escherichia coli bacterial biofilm formation through controlled expression of adhesion factors. Appl. Environl Microbiol. 73:3391-403.

 Valle, J. : Da Re, S., Henry N. ; Fontaine, T.; Balestrino, D.; Latour-Lambert, P.; and Ghigo J.M. (2006) Broad-spectrum biofilm inhibition by a secreted bacterial polysaccharide. Proc Natl Acad Sci U S 103:12558-12563.

Da Re, S. and Ghigo, J. M. (2006) A CsgD-Independent Pathway for Cellulose Production and Biofilm Formation in Escherichia coli J Bacteriol.188:3073-87.

E. G. Dudley, C. Abe, J. M. Ghigo, P. Latour-Lambert, J. C. Hormazabal and J. P. Nataro. (2006) An IncI1 Plasmid Contributes to the Adherence of the Atypical Enteroaggregative Escherichia coli Strain C1096 to Cultured Cells and Abiotic Surfaces Infect Immun.74:2102-14.

C. Beloin, K. Michaelis, K. Lindner, P. Landini, J. Hacker, J. M. Ghigo and U. Dobrindt. (2006) The Transcriptional Antiterminator RfaH Represses Biofilm Formation in Escherichia coli J Bacteriol.188:1316-31.

C. Latasa, A. Roux, A. Toledo-Arana, J. M. Ghigo, C. Gamazo, J. R. Penades and I. Lasa. (2005) BapA, a large secreted protein required for biofilm formation and host colonization of Salmonella enterica serovar Enteritidis Mol Microbiol.58:1322-39.

 • C. Beloin, S. Da Re and J. M. Ghigo. (2005) Chapter 8.3.1.3. Colonization of abiotic surfaces Escherichia coli and Salmonella. Cellular and Molecular Biology. [on line]. http://www.ecosal.org. ASM Press, Washington, D.C.

Jubelin, G., Vianney, A., Beloin., Ghigo, J.M., Lazzaroni, J.C., Lejeune, P. and C..  Dorel (2005). CpxR/OmpR Interplay regulates curli gene expression in response to osmolarity in Escherichia coli. J. Bacteriol. 187 2038-2049

Iraqui,I. ;Aubert, S. ;Dromer, F. ; Ghigo, J.M. D'enfert, C. And G. Janbon (2005) Epa6p Is A Major Adhesin Responsible For Biofilm Formation In Candida Glabrata Mol Microbiol. 55:1259-71

Roux, A, Beloin, C. and Ghigo, J.M.(2005) A combined inactivation/expression strategy to study gene function in physiological conditions: application to the identification of new adhesins in E. coli. J. Bacteriol.187:1001-1013.

C. Beloin and J. M. Ghigo. (2005) Finding gene-expression patterns in bacterial biofilms Trends Microbiol.13:16-9.

Beloin, C; J. Valle, P. Latour-Lambert, P. Faure, M. Kzreminski, D. Balestrino, J. A. Haagensen, S. Molin, G. Prensier, B. Arbeille and J. M. Ghigo. (2004) Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression Mol Microbiol.51:659-74.

Garcia-Sanchez, S.; S. Aubert, I. Iraqui, G. Janbon, J. M. Ghigo and C. d'Enfert. (2004) Candida albicans biofilms: a developmental state associated with specific and stable gene expression patterns Eukaryot Cell.3:536-45

  J. M. Ghigo. (2003.) Are there biofilm-specific physiological pathways beyond a reasonable doubt? Res Microbiol.154:1-8.

  J. Valle, A. Toledo-Arana, C. Berasain, J. M. Ghigo, B. Amorena, J. R. Penades and I. Lasa. (2003.) SarA and not sigmaB is essential for biofilm development by Staphylococcus aureus Mol Microbiol.48:1075-87.

 A. Toussaint, J. M. Ghigo and G. P. Salmond. (2003.) A new evaluation of our life-support system EMBO Rep.4:820-4.

C. Solano, B. Garcia, J. Valle, C. Berasain, J. M. Ghigo, C. Gamazo and I. Lasa. (2002.) Genetic analysis of Salmonella enteritidis biofilm formation: critical role of cellulose Mol Microbiol.43:793-808.

• J. M. Ghigo. (2001.) Natural conjugative plasmids induce bacterial biofilm development Nature.412:442-5.

 

 • Ferrieres, L., Hemery, G., Nham, T., Guerout, A. M., Mazel, D., Beloin, C. and Ghigo, J. M. (2010) Silent mischief: bacteriophage Mu insertions contaminate products of Escherichia coli random mutagenesis performed using suicidal transposon delivery plasmids mobilized by broad-host-range RP4 conjugative machinery J Bacteriol.192:6418-27.

Beloin, C., Houry, A., Froment, M., Ghigo, J. M. and Henry, N. (2008) A short-time scale colloidal system reveals early bacterial adhesion dynamics PLoS Biol.6:e167.

Da Re, S., Le Quere, B., Ghigo, J. M. and Beloin, C. (2007) Tight modulation of Escherichia coli bacterial biofilm formation through controlled expression of adhesion factors Appl Environ Microbiol.73:3391-403

Roux, A, Beloin, C. and Ghigo, J.M.(2005) A combined inactivation/expression strategy to study gene function in physiological conditions: application to the identification of new adhesins in E. coli. J. Bacteriol.187:1001-1013.

B. Lesic, S. Bach, J. M. Ghigo, U. Dobrindt, J. Hacker and E. Carniel. (2004.) Excision of the high-pathogenicity island of Yersinia pseudotuberculosis requires the combined actions of its cognate integrase and Hef, a new recombination directionality factor Mol Microbiol.52:1337-48.

A. Derbise, B. Lesic, D. Dacheux, J. M. Ghigo and E. Carniel. (2003.) A rapid and simple method for inactivating chromosomal genes in Yersinia FEMS Immunol Med Microbiol.38:113-6.

  M. K. Chaveroche, J. M. Ghigo and C. d'Enfert. (2000.) A rapid method for efficient gene replacement in the filamentous fungus Aspergillus nidulans Nucleic Acids Res.28:E97.

D. S. Weiss, J. C. Chen, J. M. Ghigo, D. Boyd and J. Beckwith. (1999.) Localization of FtsI (PBP3) to the septal ring requires its membrane anchor, the Z ring, FtsA, FtsQ, and FtsL J Bacteriol.181:508-20.

J. C. Chen, D. S. Weiss, J. M. Ghigo and J. Beckwith. (1999.) Septal localization of FtsQ, an essential cell division protein in Escherichia coli J Bacteriol.181:521-30.

 J. M. Ghigo, D. S. Weiss, J. C. Chen, J. C. Yarrow and J. Beckwith. (1999.) Localization of FtsL to the Escherichia coli septal ring Mol Microbiol.31:725-37.

J. M. Ghigo and J. Beckwith. (2000.) Cell division in Escherichia coli: role of FtsL domains in septal localization, function, and oligomerization J Bacteriol.182:116-29.

S. Letoffe, J. M. Ghigo and C. Wandersman. (1994.) Iron acquisition from heme and hemoglobin by a Serratia marcescens extracellular protein Proc Natl Acad Sci U S A.91:9876-80.

J. M. Ghigo, S. Letoffe and C. Wandersman. (1997.) A new type of hemophore-dependent heme acquisition system of Serratia marcescens reconstituted in Escherichia coli J Bacteriol.179:3572-9.

N. Wolff, P. Delepelaire, J. M. Ghigo and M. Delepierre. (1997.) Spectroscopic studies of the C-terminal secretion signal of the Serratia marcescens haem acquisition protein (HasA) in various membrane-mimetic environments Eur J Biochem.243:400-7.

A. Paquelin, J. M. Ghigo, S. Bertin and C. Wandersman. (2001.) Characterization of HasB, a Serratia marcescens TonB-like protein specifically involved in the haemophore-dependent haem acquisition system Mol Microbiol.42:995-1005.

M. S. Rossi, J. D. Fetherston, S. Letoffe, E. Carniel, R. D. Perry and J. M. Ghigo. (2001.) Identification and characterization of the hemophore-dependent heme acquisition system of Yersinia pestis Infect Immun.69:6707-17.

M. S. Rossi, A. Paquelin, J. M. Ghigo and C. Wandersman. (2003.) Haemophore-mediated signal transduction across the bacterial cell envelope in Serratia marcescens: the inducer and the transported substrate are different molecules Mol Microbiol.48:1467-80.

Biville, F.; Cwerman,  H; Rossi, M.S.; Drouet, V. Ghigo, J.M.  and C. Wandersman,(2004).The hemophore-mediated signal transduction system of Serratia marcescens: A new mode of regulation for an ECF sigma factor. Mol Microbiol. 53(4):1267-1277.

J. M. Ghigo and C. Wandersman. (1992.) A fourth metalloprotease gene in Erwinia chrysanthemi Res Microbiol.143:857-67.

J. M. Ghigo and C. Wandersman. (1992.) Cloning, nucleotide sequence and characterization of the gene encoding the Erwinia chrysanthemi B374 PrtA metalloprotease: a third metalloprotease secreted via a C-terminal secretion signal Mol Gen Genet.236:135-44.

S. Letoffe, J. M. Ghigo and C. Wandersman. (1993.) Identification of two components of the Serratia marcescens metalloprotease transporter: protease SM secretion in Escherichia coli is TolC dependent J Bacteriol.175:7321-8.

N. Wolff, J. M. Ghigo, P. Delepelaire, C. Wandersman and M. Delepierre. (1994.) C-terminal secretion signal of an Erwinia chrysanthemi protease secreted by a signal peptide-independent pathway: proton NMR and CD conformational studies in membrane-mimetic environments Biochemistry.33:6792-801.

S. Letoffe, J. M. Ghigo and C. Wandersman. (1994.) Secretion of the Serratia marcescens HasA protein by an ABC transporter J Bacteriol.176:5372-7.

J. M. Ghigo and C. Wandersman. (1994.) A carboxyl-terminal four-amino acid motif is required for secretion of the metalloprotease PrtG through the Erwinia chrysanthemi protease secretion pathway J Biol Chem.269:8979-85.

R. Binet, S. Letoffe, J. M. Ghigo, P. Delepelaire and C. Wandersman. (1997.) Protein secretion by Gram-negative bacterial ABC exporters--a review Gene.192:7-11.