Pablo PEREIRA

PUBLICATIONS

 

Coutinho, A., Pobor, G., Pettersson, S., Leandersson, T., Forsgren, S., Pereira, P., Bandeira, A. & Martinez-A., C.
T cell-dependent B cell activation
Immunol. Rev., 78 : 211-224 (1984)

Martinez-A., C., Pereira, P., Bernabé, R. R., Bandeira, A., Larsson, E. L., Cazenave, P. A. & Coutinho, A.
Internal complementarities in the immune system: regulation of the expression of helper T-cell idiotypes.
Proc. Natl. Acad. Sci. USA, 81 : 4520-4523. (1984)

Martinez-A., C., de la Hera, A., Marquez, C. & Pereira, P.
B cell activation by helper T cells. Requirements of direct cell contact.
Ann. Immunol. (Inst. Pasteur), 135D : 82-85 (1984)

Pereira, P., Larsson, E.-L., Forni, L., Bandeira, A. & Coutinho, A.
Natural effector T lymphocytes in normal mice.
Proc. Natl. Acad. Sci. USA, 82 : 7691-7695. (1985)

Bandeira, A., Pereira, P., Martinez-A., C. & Coutinho, A.
Interactions of small B lymphocytes with unprimed noncytolytic T cells: dissociation between "presentation" and growth induction.
Eur. J. Immunol., 15 : 865-872. (1985)

Toribio, M. L., de la Hera, A., Pereira, P. & Landazuri, M. O.
Modulation by lectins of cytolytic T cell function.
J. Immunol., 134 : 2179-2184. (1985)

Coutinho, A., Holmberg, D., Martinez-A., C., Freitas, A., Larsson, E.-L., Pereira, P. & Bandeira, A.
Internal activity in the immune system and its physiologic significance.
In: "Modern Trends in Human Leukemia VI", R. Neth (Ed), 477-480 (1985)

Martinez-A., C., Bernabé, R. R., De la Hera, A., Pereira, P., Cazenave, P.-A. & Coutinho, A.
Establishment of idiotypic helper T-cell repertoires early in life.
Nature, 317 : 721-723. (1985)

Martinez-A., C., Bragado, R., De la Hera, A., Toribio, M. L., Marcos, M.A. R., Bandeira, A., Pereira, P. & Coutinho, A.
Functional and biochemical evidence for the recognition of T cell receptors by monoclonal antibodies to an immunoglobulin idiotype.
J. Mol. Cell. Immunol., 2 : 307-313. (1986)

Martinez-A., C., Pereira, P., Cazenave, P.-A. & Coutinho, A.
The mutual selective influences of T- and B- cell repertoires: the idiotypic net(at) work.
Ann. Inst. Pasteur/Immunol., 137 C : 82-84. (1986)

Martinez-A., C., Pereira, P., De la Hera, A., Bandeira, A., Marquez, C. & Coutinho, A.
The basis for Major Histocompatibility Complex (MHC) and immunoglobulin gene control of helper T cell idiotopes.
Eur. J. Immunol., 16 : 417-422. (1986)

Pereira, P., Forni, L., Larsson, E. L., Cooper, M. D., Heusser, C. & Coutinho, A.
Autonomous activation of B and T cells in antigen-free mice.
Eur. J. Immunol., 16 : 685-688. (1986)

Pereira, P., Martinez-A., C., Bandeira, A., Freitas, A. & Coutinho, A.
Polyclonal B cell activation.
Bull. Inst. Pasteur, 84 : 207-232. (1986)

Pereira, P., Forsgren, S., Portnoï, D., Bandeira, A., Martinez-A., C. & Coutinho, A.
The role of immunoglobulin receptors in "cognate" T-B cell collaboration.
Eur. J. Immunol., 16 : 355-361. (1986)

Martinez-A., C., Toribio, M.L., de la Hera, A., Marquez, C., Marcos, M.A.R., Coutinho, A. & Pereira, P.
Idiotype sharing between B and T lymphocytes reflects autonomous self responses with the immune system.
In: "International Conference on Idiotypes", D. Capra & M. Reichlin (eds.), 263-274 (1986)

Martinez-A., C., Pereira, P., De la Hera, A., Toribio, M. L., Marcos, M. A.R., Marquez, C. & Coutinho, A.
A common idiotype on T cell receptors and antibodies expressed in the absence of network selection.
Eur. J. Immunol., 17 : 1391-1394. (1987)

Bandeira, A., Larsson, E.-L., Forni, L., Pereira, P. & Coutinho, A.
"In vivo" activated splenic T cells are refractory to interleukin 2 growth "in vitro".
Eur. J. Immunol., 17 : 901-908. (1987)

Martinez-A., C., Coutinho, A., Bandeira, A., De la Hera, A., Toribio, M.L., Marcos, M. A. R. & Pereira, P.
Sporadic idiotypic cross-reactivities between antibodies and T helper cells: one example of aleatory expression of T cell idiotypes.
J. Mol. Cell. Immunol., 3 : 21-28. (1987)

Martinez-A., C., Marcos, M. A. R., Pereira, P., Marquez, C., Toribio, M.L., De la Hera, A., Cazenave, P.-A. & Coutinho, A.
Turning (Ir gene) low responders into high responders by antibody manipulation of the developing immune system.
Proc. Natl. Acad. Sci. USA, 84 : 3812-3816. (1987)

Coutinho, A., Marquez, C., Araujo, P. M. F., Pereira, P., Toribio, M.L., Marcos, M. A. R. & Martinez-A., C.
A functional idiotypic network of T helper cells and antibodies, limited to the compartment of "naturally" activated lymphocytes in normal mice.
Eur. J. Immunol., 17 : 821-825. (1987)

Minoprio, P., Eisen, H., Joskowicz, M., Pereira, P. & Coutinho, A.
Suppression of polyclonal antibody production in Trypanosoma cruzi -infected mice by treatment with anti-L3T4 antibodies.
J. Immunol., 139 : 545-550. (1987)

Bandeira, A., Coutinho, A., Martinez-A., C. & Pereira, P.
The origin of "natural antibodies" and the internal activity in the immune system.
Intern. Rev. Immunol., 3 : 47-58. (1988)

Minoprio, P., Burlen, O., Pereira, P., Guilbert, B., Andrade, L., Hontebeyrie-Joskowicz, M. & Coutinho, A.
Most B cells in acute Trypanosoma cruzi infection lack parasite specificity.
Scand. J. Immunol., 28 : 553-561. (1988)

Huetz, F., Sciard-Larsson, E.-L., Pereira, P., Portnoï, D. & Coutinho, A.
T cell dependence of "natural" autoreactive B cell activation in the spleen of normal mice.
Eur. J. Immunol., 18 : 1615-1622. (1988)

Pereira, P., Larsson-Sciard, E.-L., Coutinho, A. & Bandeira, A.
Suppressor versus cytolytic CD8+ T lymphocytes: where are the artefacts ?
Scand. J. Immunol., 27 : 625-628. (1988)

Marcos, M. A. R., De la Hera, A., Pereira, P., Marquez, C., Toribio, M., Coutinho, A. & Martinez-A., C.
B cell participation in the recursive selection of T cell repertoires.
Eur. J. Immunol., 18 : 1015-1020. (1988)

Martinez-A., C., Bandeira, A., Toribio, M. L., Coutinho, A., Marcos, M. A.R. & Pereira, P.
Back-stimulation of B lymphocytes binding to helper T cell surface antigens.
Eur. J. Immunol., 18 : 2895-1899. (1988)

Martinez-A., C., Pereira, P., Toribio, M. L., Marcos, M. A. R., Bandeira, A., De la Hera, A., Marquez, C., Cazenave, P.-A. & Coutinho, A.
The participation of B cells and antibodies in the selection and maintenance of T cell repertoires.
Immunol. Rev., 101 : 191-215. (1988)

Freitas, A., Pereira, P., Huetz, F., Thomas-Vaslin, V., Pena-Rossi, C., Andrade, L., Sundblad, A., Forni, A. & Coutinho, A.
B cell activities in normal unmanipulated mice.
In: "B lymphocytes: function and regulation", P. del Guercio & J.M. Cruse (eds.), Contrib. Microbiol. Immunol. Basel, Karger, 11 : 1-26 (1989)

Bandeira, A., Martinez-A., C., Pereira, P., Larsson-Sciard, E.-L. & Coutinho, A.
Questions on the emergence of T cell repertoires.
In: "Immunology of the fetus", G. Chaouat (ed.), CRC Press, 5-10 (1989)

Minoprio, P., Bandeira, A., Pereira, P., Mota Santos, T. & Coutinho, A.
Preferential expansion of Ly-1 B and CD4- CD8- T cells in the polyclonal lymphocyte responses to murine T. cruzi infection.
Intern. Immunol., 1 : 175-184. (1989)

Rocha, B., Dautigny, N. & Pereira, P.
Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios "in vivo".
Eur. J. Immunol., 19 : 905-911. (1989)

Pena-Rossi, C., Pereira, P., Portnoï, D. & Coutinho, A.
MHC-linked and T cell-dependent selection of antibody repertoires. Quantitation of I-E-related specificities in normal mice.
Eur. J. Immunol., 19 : 1941-1946. (1989)

Pereira, P., Bandeira, A., Coutinho, A., Marcos, M. A. R., Toribio, M. L. & Martinez-A., C.
V-region connectivity in T cell repertoires.
Ann. Rev. Immunol., 7 : 209-249. (1989)

Pereira, P., Bandeira, A., Kleine, B., Marquez, C., Coutinho, A. & Martinez-A., C.
A model system for the analysis of B-cell activation and effector T-cell functions. T cell-dependent B-cell responses facilitated by anti-I-A antibodies.
Scand. J. Immunol., 29 : 49-56. (1989)

Pereira, P. & Coutinho, A.
I-E-linked control of spontaneous rheumatoid factor production in normal mice.
J. Exp. Medicine., 170 : 1825-1836. (1989)

Marcos, M. A. R., Huetz, F., Pereira, P., Andreu, J. L., Martinez-A., C. & Coutinho, A.
Further evidence for coelomic-associated B lymphocytes.
Eur. J. Immunol., 19 : 2031-2035. (1989)

Coutinho, A., Bandeira, A., Pereira, P., Portnoi, D., Holmberg, D., Martinez, C. & Freitas, A.
Selection of lymphocyte repertoires: the limits of clonal versus network organization.
In: "Symposia on quantitative biology", Cold Spring Harbor Laboratory, N.Y., 54 : 159-170 (1989)

Dietrich, G., Pereira, P., Algiman, M., Sultan, Y. & Kazatchkine, M. D.
A monoclonal anti-idiotypic antibody against the antigen-combining site of anti-factor VIII autoantibodies defines an idiotope that is recognized by normal human polyspecific immunoglobulins for therapeutic use (IVIg).
J. Autoimmun., 3 : 547-557. (1990)

Gaspar, M. L., Marcos, M. A. R., Pereira, P., Toribio, M. L., Coutinho, A. & Martinez-A, C.
Selective expansion of idiotype sharing T and B cells in cyclosporin A-mediated autoimmunity.
Intern. Immunol., 3 : 777-784. (1991)

Pereira, P. & Rocha, B.
Post-thymic in vivo expansion of mature ab T cells.
Int. Immunol., 3 : 1077-1080. (1991)

Pereira, P., Zijlstra, M., McMaster, J., Loring, J. M., Jaenisch, R. & Tonegawa, S.
Blockade of transgenic gd T cell development in b2-microglobulin deficient mice.
EMBO J., 11 : 25-31. (1992)

Haas, W., Pereira, P. & Tonegawa, S.
gd T cells.
Ann. Rev. Immunol., 11 : 625-673. (1993)

Spaner, D., Migita, K., Ochi, A., Shannon, J., Miller, R. G., Pereira, P., Tonegawa, S. & Phillips, R. A.
gd T cells differentiate into a functional but nonproliferative state during a normal immune response.
Proc. Natl. Acad. Sci. USA, 90 : 8415-8419. (1993)

Modigliani, Y., Pereira, P., Thomas-Vaslin, V., Salaün, J., Burlen-Defranoux, O., Coutinho, A., Le Douarin, N. & Bandeira, A.
Regulatory T cells in thymic epithelium-induced tolerance. I. Suppression of mature peripheral non-tolerant T cells.
Eur. J. Immunol., 25 : 2563-2571. (1995)

Pereira, P., Gerber, D., Ying Huang, S. & Tonegawa, S.
Ontogenic development and tissue distribution of Vg1-expressing g/d T lymphocytes in normal mice.
J. Exp. Med., 182 : 1921-1930. (1995)

Gerber, D. J., Pereira, P., Huang, S. Y., Pelletier, C. & Tonegawa, S.
Expression of ab and b3 integrin chains on murine lymphocytes.
Proc. Natl. Acad. Sci. USA, 93 : 14698-14703. (1996)

Modigliani, Y., Coutinho, A., Pereira, P., Le Douarin, N., Thomas-Vaslin, V., Burlen-Defranoux, O., Salaün, J. & Bandeira, A.
Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium.
Eur. J. Immunol., 26 : 1807-1815. (1996)

Pereira, P., Gerber, D., Regnault, A., Huang, S. Y., Hermitte, V., Coutinho, A. & Tonegawa, S.
Rearrangement and expression of Vg1, Vg2, and Vg3 TCR g genes in C57BL/6 mice.
Int. Immunol., 8 : 83-90. (1996)

Pereira, P., Lafaille, J. J., Gerber, D. & Tonegawa, S.
The T cell receptor repertoire of intestinal intraepithelial g/d T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci.
Proc. Natl. Acad. Sci. USA, 94 : 5761-5766. (1997)

Azuara, V., Levraud, J.-P., Lembezat, M.-P. & Pereira, P.
A novel subset of adult gd thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire.
Eur. J. Immunol., 27 : 544-553. (1997)

Malissen, M., Pereira, P., Gerber, D. J., Malissen, B. & Di Santo, J. P.
The common cytokine receptor g chain controls survival of g/d T cells.
J. Exp. Med., 186 : 1277-1285. (1997)

Zuany-Amorim, C., Ruffié, C., Hailé, S., Vargaftig, B.B., Pereira, P. & Pretolani, M.
Requirement for gd T cells in allergic airway inflammation.
Science, 280 : 1265-1267 (1998)

Azuara, V., Lembezat, M.-P. & Pereira, P.
The homogeneity of the TCRd repertoire expressed by the Thy-1dull gd T cell population is due to cellular selection.
Eur. J. Immunol., 28 : 3456-3467 (1998)

Gerber, D., Azuara, V., Levraud, J.-P., Huang, S.Y., Lembezat, M.-P. & Pereira, P.
IL-4-producing gd T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen.
J. Immunol., 163 : 3076-3082 (1999)

Azuara, V. & Pereira, P.
Genetic mapping of two murine loci that influences the development of IL-4-producing Thy-1dull gd thymocytes
J. Immunol., 165 : 42-48 (2000)

Pereira, P., Hermitte, V., Lembezat, M.-P., Boucontet, L., Azuara, V. & Grigoriadou, K.
Developmentally regulated and lineage-specific rearrangement of T cell receptor Va/d gene segments.
Eur. J. Immunol., 30 : 1988-1997 (2000)

Azuara, V., Grigoriadou, K., Lembezat, M.-P., Nagler-Anderson, C. & Pereira, P.
Strain-specific TCR repertoire selection of IL-4-producing Thy-1dull gd thymocytes.
Eur. J. Immunol. 31 : 205-214 (2001)

Grigoriadou, K., Boucontet, L. & Pereira, P.
T cell receptor-g allele-specific selection of Vg1/Vd4 cells in the intestinal epithelium.
J. Immunol., 169 : 3736-3743 (2002)

Grigoriadou, K., Boucontet, L. & Pereira P.
Most IL-4-producing gd thymocytes of adult mice originate from fetal precursors
J. Immunol. 171 : 2413-2420 (2003)

Gerber, D., Boucontet, L. & Pereira, P.
Early expression of a functional TCRb chain inhibits TCRg gene rearrangements without altering the frequency of TCRgd lineage cells
J. Immunol. 173 : 2516-2523 (2004)

Pereira, P. & Boucontet L.
Rates of recombination and chain pair biases greatly influence the primary gd TCR repertoire in the thymus of adult mice
J. Immunol. 173 : 3261-3270 (2004)

Boucontet, L., Sepulveda, N., Carneiro J. & Pereira, P.
Mechanisms controlling termination of V-J recombination at the TCRg locus : implications for allelic and isotypic exclusion of TCRg chains.
J. Immunol. 174 : 3912-3919 (2005)

Sepulveda, N., Boucontet, L., Pereira, P. & Carneiro, J.
Stochastic modeling of T cell receptor g gene rearrangement.
J. Theor. Biol. 234 : 153-165 (2005)

Shin, S., El-Diwany, R., Schaffert, S., Adams, E.J., Garcia, K.C., Pereira, P. & Chien, Y.-H.
Antigen recognition determinants of gd T cell receptors.
Science 308 : 252-255 (2005)

Boucontet, L., Grana, M., Alzari, P.M. & Pereira, P.
Mechanisms determining cell membrane expression of different gd TCR chain pairings
Eur. J. Immunol., 39 : 1937-1946 (2009)

Kreslavsky, T., Savage, A., Hobbs, R., Gounari, F., Bronson, R., Pereira, P., Pandolfi, P.P., Bendelac,  A. &  von Boehmer, H.
TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gd T cells with restricted TCR diversity.
PNAS 106 : 12453-12458 (2009)

Alonzo E.S., Gottschalk R.A., Das J., Egawa T., Hobbs R.M., Pandolfi P.P., Pereira P., Nichols K.E., Koretzky G.A., Jordan M.S. & Sant’Angelo D.B.
Development of promyelocytic zinc finger and ThPOK-expressing innate gd T cells is controlled by strength of TCR signaling and Id3.
J. Immunol. 184 : 1268-1279 (2010)

Verykokakis M., Boos M.D., Bendelac A., Adams E.J., Pereira P. & Kee B.L.
Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent « innate » gd T cells.
PLoS ONE 5 : e9303 (2010)

Ribeiro V.S.G., Hasan M., Wilson A., Boucontet L., Pereira P., Lesjean-Pottier S., Satoh-Takayama N., Di Santo J.P. & Vosshenrich C.A.J.
Cutting edge : thymic NK cells develop independently from T cells precursors
J. Immunol. 185 : 4993-4997 (2010)

Ma Y., Aymeric L., Locher C., Mattarollo S.R., Delahaye N.F., Pereira P., Boucontet L., Apetoh L., Ghringhelli F., Casares N., Lasarte J.J., Matsuzaki G., Ikuta K., Ryffel B., Benlagha K., Tesniere A., Ibrahim N., Déchanet-Merville J., Chaput N., Smith M.J., Kroemer G. & Zitvogel L.
Contribution of IL-17-producing γδ T cells to the efficacy of anticancer chemotherapy
J. Exp. Med. 208 : 491-503 (2011)

Pereira P., Boucontet L. & Cumano A.
Temporal predisposition to αβ and γδ T cell fates in the thymus.
J. Immunol. 188 : 1600-1608 (2012)

Pereira P. & Boucontet L.
Innate NKTγδ and NKTαβ cells exert similar functions and compete for a thymic niche
Eur. J. Immunol. 42 : 1272-1281 (2012)

Chen Y., Ci, X., Gorentla B., Sullivan S.A., Stone J.C., Zhang W., Pereira P., Lu J. & Zhong X.-P.
Differential requirement of RasGRP1 for γδ T cell development and activation.
J. Immunol. 189 : 61-71 (2012)