Sylvie GARCIA

Liste des publications

Revues internationales à comité de lecture :

1- Gougeon, M.L., Olivier, R., Garcia, S., Guétard, D., Dragic, T., Dauguet, C. & Montagnier, L. Mise en évidence d'un processus d'engagement vers la mort cellulaire par apoptose dans les lymphocytes de patients infectés par le VIH. C.R. Acad. Sci. 312 : 529 (1991)

2- Gougeon, M.L., Garcia, S., Heeney, J., Tschopp, R., Lecoeur, H., Guetard, D., Rame, V., Dauguet, C. & Montagnier, L. Programmed Cell Death in AIDS-related HIV and SIV infections. AIDS Res. and Hum. Retrov. 9 : 553 (1993)

3- Gougeon, M.L., Dadaglio, G., Garcia, S., Roue, R., Müller-Alouf, H. & Montagnier L. Is a dominant superantigen involved in AIDS pathogenesis? Lancet 342 : 50 (1993)

4- Dadaglio, G., Garcia, S., Montagnier, L. & Gougeon, M.L. Selective anergy of Vß8+ T cells in asymptomatic HIV-infected individuals. Journal of Experimental Medicine 179 : 413 (1994)

5- Sasaki, Y., Blanchard, A., Watson, H.L., Garcia, S., Dulioust, A., Montagnier, L. & Gougeon, M.L. In vitro influence of Mycoplasma Penetrans on activation of peripheral T lymphocytes from healthy donors or human immunodeficiency virus-infected individuals. Infection and Immunity 63 : 4277 (1995)

6- Garcia, S., Dadaglio, G., Cilote, V., Lafeuillade, A. & Gougeon, M.L. Evidence for an in vivo superantigenic activity in HIV-infected individuals. Blood 88 : 2151 (1996)

7- Garcia, S., Dadaglio, G. & Gougeon, M.L. The limits of the Hu-PBL-SCID model: severe restriction of the Vß repertoire of engrafted human T cells. Blood 89 : 329 (1996)

8- Buseyne, F., Michèle, F., Garcia, S., Gougeon, M-L. & Rivière, Y. Dual function of a human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte clone: inhibition of HIV replication by noncytolytic mechanisms and lysis of HIV-infected CD4+ cells. Virology 225 : 248 (1996)

9- Garcia, S., Février, M., Dadaglio, G., Lecoeur, H., Rivière, Y. & Gougeon, M-L. Potential deleterious effect of anti-viral cytotoxic lymphocyte through the CD95 (FAS/APO-1)-mediated pathway during chronical HIV infection. Immunology Letters 57 : 53 (1997)

10- Ledru, E., Lecoeur, H., Garcia, S., Debord, T. & Gougeon, M-L. Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: correlation with Bcl-2 expression and consequences for AIDS pathogenesis. Journal of Immunology 160 : 3194 (1998)

11- Weiss, L., Roux, A., Garcia, S., Demouchy, C., Haeffner-Cavaillon, N., Kazatchkine, M-D. & Gougeon, M-L. Persistent expansion, in a immunodefiency virus-infected person, of V beta-restricted CD4+ CD8+ T lymphocytes that express cytotoxic-associated molecules and are commited to produce interferon-gamma and tumour necrosis factor-alpha. Journal of infectious diseases 178:1158. (1998)

12- Akbari, O., Panjwani, N., Garcia, S., Tascon, R., Lowrie, D. & Stockinger, B. DNA vaccination: Transfection and activation of dendritic cells as key events for immunity. Journal of Experimental Medicine189 : 169 (1999)

13- Garcia, S., DiSanto, J. & Stockinger, B. Following the development of a CD4 T cell response in vivo: from activation to memory formation. Immunity 11 : 163 (1999)

14- Panjwani, N., Akbari, O., Garcia, S., Brazil, M. & Stockinger, B. The HSC73 molecular chaperone: involvement in MHC Class II antigen presentation. Journal of Immunology 163 : 1936 (1999)

15- Ferreira, C., Barthlott, T., Garcia, S., Zamoyska, R. & Stockinger, B. Differential maintenance of naive CD4 and CD8 in normal and T cell receptor transgenic mice. Journal of Immunology 165 : 3689 (2000)

16- Lecoeur, H., Février, M., Garcia, S., Rivière, Y. & Gougeon, M.L. A novel flow cytometric assay for quantitation and multiparametric characterization of cell-mediated cytotoxicity. Journal of Immunological Methods 253 : 177 (2001)

17- Kassioutis, G., Garcia, S., Simpson, E. & Stockinger. B. Impairment of immunological memory in the absence of MHC despite survival of memory T cells. Nat Immunol. 3 : 244-250 (2002)

18- de Oliveira Pinto, L,M,, Garcia, S., Lecoeur, H., Rapp, C. &, Gougeon, M.-L. Increased sensitivity of T lymphocutes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection : relation to expression of Bcl-2 and active caspase-8 and caspase-3. Blood 99 : 1666-1675 (2002)

19- Ledru, E., Février, M., Lecoeur, H., Garcia, S., Boullier, S. & Gougeon M.-L. A nonsecreted variant of interleukin-4 is associated with apoptosis : implication for the T helper-2 polarization in HIV infection. Blood 101 : 3102-3105 (2003)

20- Schlecht, G., Garcia, S., Escriou, N., Freitas, A.A., Leclerc C. & Dadaglio, G. Murine plasmacytoid dendritic cells Cs induce effector/memory CD8+ T cells responses in vivo after viral stimulation. Blood 104 : 1808-1815 (2004)

21- Sanchez-Guajardo, V., Borghans, J.A.M., Marquez, M.-E., Garcia, S. & Freitas, A.A. Different competitive capacities of Stat4- and Stat6-deficient CD4+ T cells during lymphopenia-driven proliferation. J. Immunol.174 : 1178-1187 (2005)

22- Sanchez-Guajardo, V., Tanchot, C., O’Malley, J.T., Kaplan, M.H., Garcia, S. & Freitas, A.A. Agonist-driven development of CD4+CD25+Foxp3+ regulatory T cells requires a second signal mediated by Stat6. J. Immunol. 178 : 7550-7556 (2007)

23- Leitao, C., Freitas, A.A. & Garcia, S. The role of TCR specificity and clonal competition during reconstruction of the peripheral T cell pool. J Immunol. 182 : 5232-5239 (2009)

24- Montaudouin, C., Boucontet, L., Mailhe-Lembezat, M.-P., Mariotti-Ferrandiz, M.-E., Louise, A., Six, A., Freitas, A.A. & Garcia, S. Endogenous TCR recombination in TCR Tg single Rag-deficient mice uncovered by robust in vivo T cell activation and selection. PLoS ONE 5 : e10238 (2010)

25- Pere, H., Montier, Y., Bayri, J., Quintin-Colonna, F., Merillon, N., Dransart, E., Badoual, C., Gey, A., Ravel, P., Marcheteau, E., Batteux, F., Sandoval, F., Adotevi, O., Chiu, C., Garcia, S., Tanchot, C., Lone, Y.C., Ferreira, L.C., Nelson, B.H., Hanahan , D., Fridman, W.H., Johannes, L. & Tartour, E. A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens. Blood 118 : 4853-4862 (2011)

26- Garcia, S. & Freitas, A.A. Humanized mice : current states and perspectives. Immunol. Letters 146 : 1-7 (2012)

Publications dans des ouvrages

1- Montagnier, L., Gougeon,M-L., Olivier, R., Garcia, S., Dauguet, C., Adams, M., Bechet, J-M., Guétard, D., Laurent, A., Hovanessian, A., Kirstetter, M., Roué, R., Pialoux, G. & Dupont, B. Factors and mechanisms of AIDS pathogenesis. In "Science Challenging AIDS" Ed. Rossi GB, Beth-Giraldo E, Chieco-Bianc L, Dianzani, Giraldo G, Verani P (Ed), S. Karger AG, Basel, pp. 51-70 (1992)

2- Gougeon, M-L., Garcia, S., Guétard, D., Olivier, R., Dauguet, C. & Montagnier, L. Apoptosis as a mechanism of cell death in peripheral lymphocytes from HIV-1 infected. In "Immunology of HIV infection" G. Janossy, B. Autran, F. Miedema (Ed). S. Krager AG, Basel, PP. 115-126 (1992)

3- Montagnier, L., Gougeon, M-L., Tschopp, R., Guétard, D., Lecoeur, H., Rame, V., Garcia, S., Lopez, O. & Olivier, R. New insights on the mechanisms of CD4+ lymphocytes depletion in AIDS. In "Retroviruses of Human AIDS and Related Animal Diseases" (Girard M. and Valette L., eds) pp. 19-26, Fondation M. Merieux. (1992)

4- Gougeon, M-L., Garcia, S., Heeney, J. & Montagnier, L. Programmed cell death during HIV-infection and correlation with AIDS pathogenesis. In "New concepts in AIDS pathogenesis" L. Montagnier and M.L. Gougeon Eds, Marcel Dekker, 153 : 169 (1993)

5- Gougeon, M-L., Ledru, E., Lecoeur, H. & Garcia, S. T cell apoptosis in HIV infection: mechanisms and relevance for AIDS pathogenesis. In "Results and problems in cell differentiation" 24 : 233 (1998)