François Huetz

Liste des publications / Brevets

 

PUBLICATIONS

  1. HUETZ, F. et LUCOTTE, G. (1986) Polymorphisme de restriction des gènes d' histocompatibilité de classe I chez le chimpanzé. Bioch. Syst. Ecol., 14: 681

  2. HUETZ, F., COULONDRE, C., WILLCOX, G., MULLER, J.Y., and LUCOTTE, G. (1986) Segregation analysis of polymorphic HLA class I PVU II restriction fragments. Biosciences, 5: 197

  3. HUETZ, F., LUCOTTE, G., KAHAN, A., et AMOR, B. (1987) Polymorphisme de restriction TAQ I et allèle HLA B27 dans la Spondylarthrite Ankylosante. Rev. du Rhumatisme, 54: 175

  4. HUETZ, F., MARIOTTI, M. and LUCOTTE, G. (1987) TAQ I restriction polymorphism of HLA class I genes and hybridization with HLA-A and HLA-B specific probes. Exp. Clin. Immunogen., 4: 1

  5. HUETZ, F., SCIARD-LARSSON, E-L., PEREIRA, P., PORTNOI, D. and COUTINHO, A. (1988) T cell dependence of "natural" auto-reactive B cell activation in the spleen of normal mice. Eur. J. Immunol. , 18: 1615-1622.

  6. HUETZ, F., JACQUEMART, F., PENA ROSSI, C., VARELA, F. and COUTINHO, A. (1988) Autoimmunity: The moving boundaries between physiology and pathology. J. Autoimmunity, 1: 507-518. and in "Immunointervention in autoimmune diseases", BACH, J. F. (Ed.) Academic Press.

  7. FREITAS, A., PEREIRA, P., HUETZ, F., THOMAS-VASLIN, V., PENA-ROSSI, C., ANDRADE, L., SUNDBLAD, A., FORNI, L. and COUTINHO, A. (1989) B cell activities in normal unmanipulated mice. In " B lymphocytes : function and regulation ", Contrib Microbiol Immunol. Basel, Karger, DEL GUERCIO, P., CRUSE, J.M. (Ed.), 11: 1-26.

  8. HUETZ, F., PONCET, P., COUTINHO, A. and PORTNOI, D. (1989) Ontogenic development of auto-antibody repertoires: examples of T cell-dependent and independent reactivities.Eur. J. Immunol., 19: 1195-1201.

  9. HUETZ, F., and PONCET, P. (1989) Immunocompetence of peritoneal B cells.Res. Immunol., 140: 75-87.

  10. ANDRADE, L., FREITAS, A.A., HUETZ, F., PONCET, P., and COUTINHO, A. (1989) Immunoglobulin VH-gene expression in LY-1 and conventional B lymphocytes. Eur. J. Immunol., 19: 1117-1122.

  11. MARCOS, M.A.R., HUETZ, F., PEREIRA, P., ANDREU, J.L., MARTINEZ-A., C. and COUTINHO, A. (1989) Further evidence for coelomic-associated B lymphocytes.Eur. J. Immunol., 19: 2031-2035.

  12. WEKSLER, M., E., SCHWAB, R., HUETZ, F. and COUTINHO, A. (1989) Cellular basis of autoantibody production in old mice. Trans. Assoc. Amer. Phys., 102: 55-58.

  13. MARCOS, M.A.R., SUNDBLAD, A., GRANDIEN, A. HUETZ, F., AVRAMEAS, S. and COUTINHO, A. (1989) The physiology of autoimmune reactivities.Progress in Immunol., 7: 793-804.

  14. WEKSLER, M., E., SCHWAB, R., HUETZ, F., KIM, Y.T. and COUTINHO, A. (1990) Cellular basis for the age-associated increase in autoimmune reactions.Int. Immunol., 2: 329-335.

  15. MASMOUDI, H., MOTA-SANTOS, T, HUETZ, F., COUTINHO, A. & CAZENAVE, P.A. (1990) All T15 Id positive antibodies (but not the majority of VH T15+ antibodies) are produced by peritoneal CD5+ B lymphocytes. Int. Immunol., 2: 515-520.

  16. PONCET, P., HUETZ, F., MARCOS, M.A.R. & ANDRADE, L. (1990) All VH11 genes expressed in peritoneal lymphocytes encode anti-BrMRBC autoantibodies but other VH gene families can also contribute to this specificity. Eur. J. Immunol., 20: 1583-1590.

  17. SUNDBLAD, A., HUETZ, F., PORTNOI, D. & COUTINHO, A. (1991) Stimulation of B and T cells by in vivo high dose immunoglobulin administration in normal mice. J. Autoimmunity., 4: 325-339.

  18. MARCOS, M. A. R., GUTIERREZ, J. C., HUETZ, F., MARTINEZ-A, C. & DIETERLEN-LIEVRE, F. (1991) Waves of B-lymphopoiesis in the establishment of the mouse B-cell compartment. Scan. J. Immunol., 34: 129-135.

  19. SUNDBLAD, A., MARCOS, M.A., HUETZ, F., FREITAS, A., HEUSSER, C., PORTNOI, D. & COUTINHO, A. (1991) Normal serum immunoglobulins influence the numbers of bone marrow pre-B and B cells. Eur. J. Immunol., 21: 1155-1161.

  20. ANDRADE, L., HUETZ, F., PONCET, P., THOMAS-VASLIN, V., GOODHEART, M. & COUTINHO, A. (1991) Biased VH gene expression in murine CD5 B cells results from age-dependent cellular selection. Eur. J. Immunol., 21: 2017-2024.

  21. THOMAS-VASLIN, V., COUTINHO, A. and HUETZ, F. (1992) Origin of natural IgM secreting cells: Reconstitution potential of adult bone marrow, spleen and peritoneal cells. Eur. J. Immunol., 22: 1243-1251

  22. MARCOS, M.A.R., MALANCHERE, E., SUNDBLAD, A., HUETZ, F., GRANDIEN, A. MARTINEZ-A, C. and COUTINHO, A. (1992) Coelomic and bone marrow-derived B cells: Developmental constrainsts versus antigen-specific selection. In "CD5 B Cells in Development and Disease", HERZENBERG, L.A., HAUGHTON, G., RAJEWSKY, K. (Ed.), Annals of the New York Academy of Sciences, 651: 433-442.

  23. HUETZ, F., CARLSSON, L., TORNBERG, U-C. and HOLMBERG, D. (1993) V-region directed selection in differentiating B lymphocytes. EMBO J. ,12: 1819-1826.

  24. SUNDBLAD, A., MARCOS, M.-A.R., MALANCHERE, E., CASTRO, A., HAURY, M., HUETZ, F., NOBREGA, A., FREITAS, A. and COUTINHO, A. (1994) Observations on the mode of action of normal immunoglobulin at high doses. Immunological rev., 139: 125-158.

  25. VIALE, A.-C., CHIES, J. A. B., HUETZ, F., MALANCHERE, E., WEKSLER, M., FREITAS, A. A., and COUTINHO, A. (1994) VH-gene family dominance in ageing mice. Scand. J. Immunol., 39: 184-188.

  26. RYELANDT, M., DE WIT, D., BAZ, A., VANSANTEN, G., DENIS, O., HUETZ, F., NISOL, F., MACEDO-SOARES, F., BARCY, S., BRAIT, M., LEO, O., BAZIN, H. AND URBAIN, J. (1995) The perinatal presence of antigen (p-azophenylarsonate) or anti-µ antibodies lead to the loss of the recurrent idiotype (CRIA) in A/J mice. Int. Immunol., 7: 645-652.

  27. HUETZ, F., TORNBERG, U.-C., MALANCHERE, E., ROES, J., CARLSSON, L., COUTINHO, A., HOLMBERG, D., AND RAJEWSKY, K. (1997) Targeted disruption of the VH 81X gene: Influence on the B-cell repertoire. Eur. J. Immunol., 27: 307-314.

  28. MALANCHERE, E., HUETZ, F., AND COUTINHO, A. (1997) Maternal IgGs stimulate B-lineage cell development in the progenies. Eur. J. Immunol., 27: 788-793.

  29. HOLMBERG, D., CARLSSON, L., HUETZ, F., and TORNBERG, U-C. (1997) Immunoglobulin variable region repertoire development. In "WEIR'S Handbook of Experimental Immunology", 5TH Edition, HERZENBERG, L.A., WEIR, D.M., HERZENBERG, L.A. and BLACKWELL, C. (Ed.), CHAP 17, 17:1-17:8.

  30. GRILLOT-COURVALIN, C., GOUSSARD, S., HUETZ, F., OJCIUS, M. D., AND COURVALIN, P. (1998) Functional gene transfer from intracellular bacteria to mammalian cells Nature Biotech., 16: 862-866.

  31. BARBACCI, E., REBER, M., OTT, M-O., BREILLAT, C., HUETZ, F., and CEREGHINI, S. (1999) Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification Development, 126: 4795-4805.

  32. GOUDEAU, B., HUETZ, F., SAMSON, S., DI SANTO, J.P., CUMANO, A., BEG, A., ISRAËL, A. AND MEMET, S. (2003) IΚBα/IΚBε-deficiency reveals that a critical NF-ΚB dosage is required for lymphocyte survival P.N.A.S., 100: 15800-15805.

  33. LIM, A., LEMERCIER, B, WERTZ, X., LESJEAN-POTTIER, S., HUETZ, F., AND P. KOURILSKY, P., (2008) Many human peripheral VH5-expressing IgM+ B cells display a unique heavy-chain rearrangement. Int Immunol 20:105-116.

  34. RANDRIANARISON-HUETZ, V., LAURENT, B., BARDET, V., BLOBE, G.C., HUETZ, F., AND DUMENIL, D., (2010) GFI-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-ß signaling at the bipotent erythro-megakaryocytic progenitor stage. Blood, 115:2784-2795.

  35. BOUCHERMA, R., KRIDANE-MILEDI, H., LANGA VIVES, F., VAUCHY, C., BORG, C., KLEINCLAUSS, F., FIETTE, L., TIBERGHIEN, P., LEMONNIER, F. A., ROHRLICH, P.-S., AND HUETZ, F. (2012) Exploring the immunological interface of HFE, an MHC class Ib molecule that control iron metabolism, with anti-HFE TCR transgenic Eur. J. Immunol. 42 : 851-862

  36. REYNAUD, C.-A., DESCATOIRE, M., DOGAN, I., HUETZ, F., WELLER, S., AND WEILL, J.-C. (2012) IgM Memory B cells : The mouse/human paradox. Cellular and Molecular Life Sciences 69 : 1625-1634

  37. MAHEVAS, M., PATIN, P., HUETZ, F., DESCATOIRE, M., CAGNARD, N., BOLE-FEYSOT, C., LE GALLOU, S., KHELLAF, M., FAIN, O., BOUTBOUL, D., GALICIER, L., EBBO, M., LAMBOTTE, O., HAMIDOU, M., BIERLING, P., GODEAU, B., MICHEL, M., WEILL, J.-C. & REYNAUD, C.-A. (2013) B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells. J. Clinical Invest. 123 : 432-442

BREVET

Brevet Européen :« Repertoire determination of a lymphocyte B population » N° de dépôt : 03293159.4 Date du dépôt : 15 Décembre 2003