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Institution
The Peking Union medical College Hospital (PUMCH)
has been created in 1921 with the support of the Rockfeller Foundation.
It is a 2000-bed hospital with a 3300 staff: 1.5 million outpatients/year
and 30000 inpatients/year. The Department of Infectious Diseases
has a 35-bed unit and 32 staff members; it reported the first AIDS
case in China in 1985. It has laboratory facilities including flow
cytometers, rooms for extraction, amplification of DNA, a BSL3.
Several international collaborations are on-going, most of them
focussed on AIDS:NIH HIV/AIDS Clinical Research Centre for the Chinese
CIPRA project and INCO EC project on HIV/AIDS Vaccination research
(CHIVAC). The Department of Infectious Diseases at PUMCH played
a pivotal role in taking care of SARS patients, making recommendations
for hospital infection control measures to prevent transmission
of SARS to health care workers.
Participants
Dr LI Taisheng is associate professor and vice-director
of the Department of Infectious Diseases at PUMCH. He is the director
of the AIDS Center for diagnosis and treatment at PUMCH. He was
trained in Internal Medicine and Infectious Diseases and he got
a PhD in Clinical Immunology at the University Pierre et Marie Curie
in Paris. He was early involved in the fight against SARS during
the winter 2003 epidemic occurring in Beijing.
Roles in the project
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Expertise in infectious diseases, clinical
immunology, treatment of SARS patients, hospital infection control
measures (WP 7 and 10, leader of the WP 9)
Publications
6 Recent publications:
1. Li TS et al, Significant changes of peripheral T lymphocyte subsets
in patients with Severe Acute Respiratory Syndrome. J Infect Dis,
2004 ;189 :648-51.
2. Li TS et al, The alterations of T cell subsets
of severe acute respiratory syndrome during acute phase. Chin J
Lab Med, 2003;26:297-99.
3. Liu ZY, Li TS et al, The clinical features and
therapy of 106 cases of severe acute respiratory syndrome. Chin
J Intern Med, 2003;42:373-77.
4. Li TS et al, The rapid loss of both CD4+ and
CD8+ T lymphocyte subsets during acute phase of severe acute respiratory
syndrome. Chin Med Journal, 2003;116:985-87.
5. 5. Autran B, Carcelain G, Li TS et al. Positive
effects of combined antiretroviral therapy on CD4+ T cell homeostasis
and function in advanced HIV disease. Science. 1997, 277:112-16.
6. Li TS, Tubiana R, Katlama C et al. Long lasting
recovery in CD4+ T cell function minors viral load reduction after
highly active anti-retroviral therapy in patients with advanced
HIV disease. Lancet. 1998, 351: 1682-86.
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