EPISARS

Prevention of future SARS epidemics through the control of animal and human infection



 

 


College of Life Sciences, Peking University

 


Institution

Peking University is a comprehensive and National key university. The University consists of 30 colleges and 12 departments, with 93 specialties for undergraduates, 2 specialties for the second Bachelor's degree, 199 specialties for Master candidates and 173 specialties for Doctoral candidates. While still laying stress on basic sciences, the university has paid special attention to the development of applied sciences. At present, Peking University has 216 research institutes and research centres, and there are 2 national engineering research centres, 81 key national disciplines, 12 national key laboratories. The University has made an effective combination of the research on important scientific issues with the training of personnel with high level specialized knowledge and professional skill. It strives not only for the simultaneous improvements in teaching and research work, but also for the promotion of interaction and mutual promotion among various subjects. Thus Peking University has become a center for teaching and research and a university of the new type, consisting of diverse branches of learning such as pure and applied sciences, social sciences and the humanities, and sciences of management and education.

 

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Participants

Dr Deng Hong-Kui is a virologist. He was trained in the USA and got his PhD from NewYork University. He previously worked on HIV/AIDS at the Skirball Institute for Biomolecular Medicine. He was involved in the SARS CoV epidemic and he supported the medical teams from PKU facing the disease. Using several SARS CoV isolated from patients, he has already developed programmes on biochemical and functional studies of viral surface proteins and search for viral entry receptors. Dr Deng and Pr Altmeyer are currently working together and complementarily on these specific topics.

 

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Roles in the project

  • Expertise in biochemical and functional virology (WP 8)

 

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Publications

Recent publications:


1. Wang P, Chen J, Zheng A, Nie Y …. Ding M, Deng H. Expression cloning of functional receptor used by SARS coronavirus. Biochem Biophys Res Commun 2004;315:439-44.

2. Deng HK, Unutmaz D, KewalRamani VN, Littman DR. Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature. 1997 Jul 17;388(6639):296-300.

3. Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P,Marmon S, Sutton RE, Hill CM,
Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR. Identification of a major co-receptor for primary isolates of HIV-1. Nature. 1996 Jun 20;381(6584):661-6.

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