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Institution
The Institute for Viral Disease Control and Prevention
was established in Beijing by decision of the Ministry of Sciences
and Technology (MOST). The institution is led by Pr DONG Xiaoping.
It has 5 BSL3 laboratories and is developing applied research such
as a serodiagnostic kit for SARS and other infectious diseases and
basic sciences with molecular virology in particular to prepare
vaccine development. The China CDC is based in Beijing but is working
at a national level to implement high standards in virological researches.
Participants
Pr Jianwei WANG is MD and PhD in virology and immunology.
He is leading the Department of Viral Diarrhea in his institution
and has moved to the respiratory virus field (SARS CoV and flu)
since the last SARS epidemic in Beijing. He has a great experience
in viral research on rotavirus and has recently developed research
on sero-epidemiology,pathogenesis, animal model and virus-cell interaction
of SARS CoV.
Participation of women: Chang Zhaorui, junior
scientist, with experiences in molecular virology.
Roles in the project
- Expertise in field of medical virology and immunology (serological
kit development).
Publications
Relevant publications:
1. Hung T, Wang JW, et al. Chlamydia-like and Coronavirus-like Agents
Found in Dead Cases of Atypical Pneumonia by Electron Microscopy.
Chin Natnl J Med, 2003, 83: 632-6
2. Wang Z, Ren LL, Zhao XG, Hung T, Meng AM, Wang
JW, and Chen YG*. Inhibition of SARS virus replication by small
interfering RNAs in mammalian cells. J Virol, 2004, in press
3. Ren LL, Wang JW, et al. Caspase dependent apoptosis
induced by SARS-CoV infection in Vero cells. Cell Res, submitted.
4. Chang ZR, Wang YB, Wang JW. Preparation and
characterization of monoclonal antibodies against N protein of SARS-CoV.
Chin J Exp Clin Virol, 2004, in press.
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