Résumé de : BISHOP (DHL), CALISHER (CH), CASALS (J), CHUMAKOV (MP), GAIDAMOVICH (SY), HANNOUN (C), LVOV (DK), MARSHALL (ID), OKER-BLOM (N), PETTERSSOM (RF), PORTERFIELD (JS), RUSSELL (PK), SHOPE (RE) & WESTAWAY - 1980 - Bunyaviridae. Intervirology, 14 (3-4), pp. 125-143.


The family Bunyaviridae comprises over 200 viruses (serotypes, subtypes, and varieties) that infect vertebrates and/or invertebrates. Four genera of viruses have been defined (Bunyavirus, Nairovirus, Phlebovirus, and Uukuvirus). The main characteristics of the member viruses are:
(I) the virus particles are for the most part uniformly spherical, 80-110 nm in diameter, and possess a unit membrane envelope from which protrude polypeptide spikes 5-10nm long;
(II) the viruses have three helical nucleocapsids, often in the form of supercoiled circles, each consisting of a single species of single-stranded RNA, major nucleocapsid polypeptide, N, and at least in some cases minor amounts of a large polypeptide which may be a transcriptase component;
(III) the genome is composed of three species of RNA (L, large; M, medium; and S, small), organized in end-hydrogen bonded circular structures;
(IV) most viruses have three major virion polypeptides (N, and two surface polypeptides, designated G1 and G2);
(V) for at least some member viruses, the virions have been shown to contain an RNA-directed RNA polymerase, believed to be responsible for the synthesis of viral complementary mRNA, so that bunyaviruses are considered to be negative-stranded viruses;
(VI) at least some bunyaviruses are capable of heterologous virus genome segment reassortment and can form recombinant viruses at high or low frequency;
(VII) viruses appear to mature primarily at smooth membrane surfaces and accumulate in Golgi vesicles and saccules, or nearby;
(VIII) transovarial, venereal and/or transstadial transmission in arthropods has been shown to occur for some members of the family.