ORIGINE :
Isolé par RE MONTGOMERY, Kabete (Kenya), à partir d'un prélèvement de sérum effectué sur un porc.
Prélevement effectué en Juin 1910, probablement sur un porc malade.
Lieu de collecte : Kenya.
ISOLEMENT :
Inoculation parentérale sur porc et sur cultures cellulaires.
Il n'y a pas de souche prototype, les isolements à partir de porcs, de tiques et de phacochères ont été nombreux.
IDENTIFICATION :
Cette souche ne présente aucun lien antigénique avec aucun des virus auxquels elle a été comparée.
Aucun anticorps neutralisant n'est produit par aucune espèce.
MALADIE :
Humaine inconnue.
Animale : Fièvre, anorexie, cyanose de la peau, destruction d'éléments lymphoréticulocitaires, vasculite, hémorragies disséminées, occasionnellement thrombose.
HOTES OU VECTEURS :
Mammifères : Hylochère, Porc, Phacochère, Potamochère.
Tiques : Ornithodoros erraticus, Ornithodoros moubata porcinus.
DISTRIBUTION GEOGRAPHIQUE :
Afrique, Espagne, Portugal (temporairement France, Italie, Cuba).
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2 - AFONSO (CL), PICCONE (ME), ZAFFUTO (KM), NEILAN (J), KUTISH (GF), LU (Z), BALINSKY (CA), GIBB (TR), BEAN (TJ), ZSAK (L) & ROCK (DL) - 2004 - African swine fever virus multigene family 360 and 530 genes affect host interferon response. Journal of Virology, 78 (4): pp. 1858-1864. Résumé
3 - ALCAMI (A) & VINUELA (E) - 1991 - Fc Receptors Do Not Mediate African Swine Fever Virus Replication in Macrophages. Virology, 181: 2 (APR 1991), pp. 756-759. Résumé
4 - ALCARAZ (C), BRUN (A), RUIZ-GONZALVO (F) & ESCRIBANO (JM) - 1992 - Cell Culture Propagation Modifies the African Swine Fever Virus Replication Phenotype in Macrophages and Generates Viral Subpopulations Differing in Protein P54. Virus Research, 23: 1-2 (APR 1992), pp. 173-182. Résumé
5 - ALEJO (A), ANDRES (G), VINUELA (E) & SALAS) (ML) - 1999 - The African swine fever virus prenyltransferase is an integral membrane trans-geranylgeranyl-diphosphate synthase. Journal of Biological Chemistry, 1999 Jun 18; 274 (25): pp. 18033-18039. Résumé
6 - ALEJO (A), ANDRES (G) & SALAS (ML) - 2003 - African swine fever virus proteinase is essential for core maturation and infectivity. Journal of Virology, 77 (10): pp. 5571-5577. Résumé
7 - ALONSO (C), MISKIN (J), HERNAEZ (B), FERNANDEZ-ZAPATERO (P), SOTO (L), CANTO (C), RODRIGUEZ-CRESPO (I), DIXON (L) & ESCRIBANO (JM) - 2001 - African swine fever virus protein p54 interacts with the microtubular motor complex through direct binding to light-chain dynein. Journal of Virology, 75 (20): pp. 9819-9827. Résumé
8 - ALONSO (F), DOMINGUEZ (J), VINUELA (E) & REVILLA (Y) - 1997 - African swine fever virus-specific cytotoxic T lymphocytes recognize the 32 KDa immediate early protein (VP32). Virus Research, 1997 Jun; 49 (2): pp. 123-130. Résumé
9 - ANDERSON (EC), HUTCHINGS (GH), MUKARATI (N) & WILKINSON (PJ) - 1998 - African swine fever virus infection of the bushpig (Potamochoerus porcus) and its significance in the epidemiology of the disease. Veterinary Microbiology, 1998 Apr 30; 62 (1): pp. 1-15. Résumé
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11 - ANDRES (G), ALEJO (A), SALAS (J) & SALAS (ML) - 2002 - African swine fever virus polyproteins pp220 and pp62 assemble into the core shell. Journal of Virology, 76 (24): pp. 12473-12482. Résumé
12 - ANDRES (G), GARCIA-ESCUDERO (R), SALAS & RODRIGUEZ (JM) - 2002 - Repression of African swine fever virus polyprotein pp220-encoding gene leads to the assembly of icosaedral core-less particles. Journal of virology, 76 (6): pp. 2654-2666. Résumé
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19 - BUSTOS (MJ), NOGAL (ML), REVILLA (Y) & CARRASCOSA (AL) - 2002 - Plaque assay for African swine fever virus on swine macrophages - Brief report. Archives of Virology, 147 (7): pp. 1453-1459. Résumé
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32 - GALINDO (I), ALMAZAN (F), BUSTOS (MJ), VINUELA (E) & CARRASCOSA (AL) - 2000 - African swine fever virus EP153R open reading frame encodes a glycoprotein involved in the hemadsorption of infected cells. Virology, 266 (2): pp. 340-351. Résumé
33 - GALINDO (I), VINUELA (E) & CARRASCOSA (AL) - 2000 - Characterization of the African swine fever virus protein p49: a new late structural polypeptide. Journal of General Virology, 81 (Part 1): pp. 59-65. Résumé
34 - GIL (S), SPAGNUOLO-WEAVER (M), CANALS (A), SEPULVEDA (N), OLIVEIRA (J), ALEIXO (A), ALLAN (G), LEITAO (A) & MARTINS (CLV) - 2003 - Expression at mRNA level of cytokines and A238L gene in porcine blood-derived macrophages infected in vitro with African swine fever virus (ASFV) isolates of different virulence. Archives of Virology, 148 (11): pp. 2077-2097. Résumé
35 - GOATLEY (LC), MARRON (MB), JACOBS (SC), HAMMOND (JM), MISKIN (JE), ABRAMS (CC), SMITH (GL) & DIXON (LK) - 1999 - Nuclear and nucleolar localization of an African swine fever virus protein, I14L, that is similar to the herpes simplex virus-encoded virulence factor ICP34.5. Journal of General Virology, 1999 Mar; 80 (Part 3): pp. 525-535. Résumé
36 - GOATLEY (LC), TWIGG (SRF), MISKIN (JE), MONAGHAN (P), St-ARNAUD (R), SMITH (GL) & DIXON (LK) - 2002 - The African swine fever virus protein j4R binds to the alpha chain of nascent polypeptide-associated complex. Journal of Virology, 76 (19): pp. 9991-9999. Résumé
37 - GOMEZ-PUERTAS (P) & ESCRIBANO (JM) - 1997 - Blocking antibodies inhibit complete African swine fever virus neutralization. Virus Research, 1997 Jun; 49 (2): pp. 115-122. Résumé
38 - GOMEZ-PUERTAS (P), OVIEDO (JM), RODRIGUEZ (F), COLL (J) & ESCRIBANO (JM) - 1997 - Neutralization susceptibility of African swine fever virus is dependent on the phospholipid composition of viral particles. Virology, 1997 Feb 17; 228 (2): pp. 180-189. Résumé
39 - GRANJA (AG), NOGAL (ML), HURTADO (C), SALAS (J), SALAS (ML), CARRASCOSA (AL) & REVILLA (Y) - 2004 - Modulation of p53 cellular function and cell death by African swine fever virus. Journal of Virology, 78 (13):pp. 7165-7174. Résumé
40 - HURTADO (C), GRANJA (AG), BUSTOS (MJ), NOGAL (ML), DE BUITRAGO (GG), DE YEBENES (VG), SALAS (ML), REVILLA (Y) & CARRASCOSA (AL) - 2004 - The C-type lectin homologue gene (EP153R) of African swine fever virus inhibits apoptosis both in virus infection and in heterologous expression. Virology, 326 (1): pp. 160-170. Résumé
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42 - JOUVENET (N), MONAGHAN (P), WAY (M) & WILEMAN (T) - 2004 - Transport of African swine fever virus from assembly sites to the plasma membrane is dependent on microtubules and conventional kinesin. Journal of Virology, 78 (15): pp. 7990-8001. Résumé
43 - KAY-JACKSON (PC), GOATLEY (LC), COX (L), MISKIN (JE), PARKHOUSE (RME), WIENANDS (J) & DIXON (LK) - 2004 - The CD2v protein of African swine fever virus interacts with the actin-binding adaptor protein SH3P7. Journal of General Virology, 85 (1): pp. 119-130. Résumé
44 - KLEIBOEKER (SB), BURRAGE (TG), SCOLES (GA), FISH (D) & ROCK (DL) - 1998 - African swine fever virus infection in the Argasid host, Ornithodoros porcinus porcinus. Journal of Virology, 1998 Mar; 72 (3): pp. 1711-1724. Résumé
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46 - KOLLNBERGER (SD), GUTIERREZ-CASTANEDA (B), FOSTER-CUEVAS (M), CORTEYN (A) & PARKHOUSE (RME) - 2002 - Identification of the principal serological immunodeterminants of African swine fever virus by screening a virus cDNA library with antibody. Journal of General Virology, 83 (6): pp. 1331-1342. Résumé
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48 - McCROSSAN (M), WINDSOR (M), PONNAMBALAM (S), ARMSTRONG (J) & WILEMAN (T) - 2001 - The trans Golgi network is lost from cells infected with African swine fever virus. Journal of Virology, 75 (23): pp. 11755-11765. Résumé
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51 - NEILAN (JG), LU (Z), KUTISH (GF), ZSAK (L), LEWIS (TL) & ROCK (DL) - 1997 - A conserved African swine fever virus I-Kappa-B homolog, 5EL, is nonessential for growth in vitro and virulence in domestic swine. Virology, 1997 Sep 1; 235 (2): pp. 377-385. Résumé
52 - NEILAN (JG), BORCA (MV), LU (Z), KUTISH (GF), KLEIBOEKER (SB), CARRILLO (C), ZSAK (L) & ROCK (DL) - 1999 - An African swine fever virus ORF with similarity to C-type lectins is non-essential for growth in swine macrophages in vitro and for virus virulence in domestic swine. Journal of General Virology, 1999 Oct; 80 (Part 10): pp. 2693-2697. Résumé
53 - NEILAN (JG), ZSAK (L), LU (Z), KUTISH (GF), AFONSO (CL) & ROCK (DL) - 2002 - Novel swine virulence determinant in the left variable region of the African swine fever virus genome. Journal of virology, 76 (7): pp. 3095-3104. Résumé
54 - NEILAN (JG), ZSAK (L), LU (Z), BURRAGE (TG), KUTISH (GF) & ROCK (DL) - 2004 - Neutralizing antibodies to African swine fever virus proteins p30, p54, and p72 are not sufficient for antibody-mediated protection. Virology, 319 (2): pp. 337-342. Résumé
55 - NETHERTON (CL), PARSLEY (JC) & WILEMAN (T) - 2004 - African swine fever virus inhibits induction of the tress-induced proapoptotic transcription factor CHOP/GADD153. Journal of Virology, 78 (19): pp. 10825-10828. Résumé
56 - OLIVEROS (M), GARCIA-ESCUDERO (R), ALEJO (A), VINUELA (E), SALAS (ML) & SALAS (J) - 1999 - African swine fever virus dUTPase is a highly specific enzyme required for efficient replication in swine macrophages. Journal of Virology, 1999 Nov; 73 (11): pp. 8934-8943. Résumé
57 - OURA (CAL), POWELL (PP) & PARKHOUSE (RME) - 1998 - African swine fever - A disease characterized by apoptosis. Journal of General Virology, 1998 Jun; 79 (Part 6): pp. 1427-1438. Résumé
58 - OURA (CAL), POWELL (PP) & PARKHOUSE (RME) - 1998 - Detection of African swine fever virus in infected pig tissues by immunochemistry and in situ hybridisation. Journal of Virological Methods, 1998 Jun; 72 (2): pp. 205-217. Résumé
59 - OURA (CAL), POWELL (PP), ANDERSON (E) & PARKHOUSE (RME) - 1998 - The pathogenesis of African swine fever in the resistant bushpig. Journal of General Virology, 1998 Jun; 79 (Part 6): pp. 1439-1443. Résumé
60 - OVIEDO (JM), RODRIGUEZ (F), GOMEZ-PUERTAS (P), BRUN (A), ALONSO (C) & ESCRIBANO (JM) - 1997 - High level expression of the major antigenic African swine fever virus proteins P54 and P30 in Baculovirus and their potential use as a diagnostic reagents. Journal of Virological Methods, 1997 Feb; 64 (1): pp. 27-35. Résumé
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63 - REVILLA (Y), CEBRIAN (A), BAIXERAS (E), MARTINEZ (C), VINUELA (E) & SALAS (ML) - 1997 - Inhibition of apoptosis by the African swine fever virus BCL-2 homologue - Role of the BH1 domain. Virology, 1997 Feb 17; 228 (2): pp. 400-404. Résumé
64 - RODRIGUEZ (CI), NOGAL (ML), CARRASCOSA (AL), SALAS (ML), FRESNO (M) & REVILLA (Y) - 2002 - African swine fever virus IAP-like protein induces the activation of nuclear factor kappa B. Journal of virology, 76 (8): pp. 3936-3942. Résumé
65 - RODRIGUEZ (JM), GARCIA-ESCUDERO (R), SALAS (ML) & ANDRES (G) - 2004 - African swine fever virus structural protein p54 is essential for the recruitment of envelope precursors to assembly sites. Journal of Virology, 78 (8): pp. 4299-4313. Résumé
66 - ROJO (G), CHAMORRO (M), SALAS (ML), VINUELA (E), CUEZVA (JM) & SALAS (J) - 1998 - Migration of mitochondria to viral assembly sites in African swine fever virus infected cells. Journal of Virology, 1998 Sep; 72 (9): pp. 7583-7588. Résumé
67 - ROJO (G), GARCIA-BEATO (R), VINUELA (E), SALAS (ML) & SALAS (J) - 1999 - Replication of African swine fever virus DNA in infected cells. Virology, 1999 May 10; 257 (2): pp. 524-536. Résumé
68 - SAANCHEZ-TORRES (C), GOMEZ-PUERTAS (P), GOMEZ-DEL-MORAL (M), ALONSO (F), ESCRIBANO (JM), EZQUERRA (A) & DOMINGUEZ (J) - 2003 - Expression of porcine CD163 on monocytes/macrophages correlates with permissiveness to African swine fever infection. Archives of Virology, 148 (12): pp. 2307-2323. Résumé
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72 - TRATSCHIN (JD), MOSER (C), RUGGLI (N) & HOFMANN (MA) - 1998 - Classical Swine fever virus leaerd proteinase N-PRO is not required for viral replication in cell culture. Journal of Virology, 1998 Sep; 72 (9): pp. 7681-7684. Résumé
73 - TULMAN (ER) & ROCK (DL) - 2001 - Novel virulence and host range genes of African swine fever virus [Review]. Current Opinion in Microbiology, 4 (4): pp. 456-461. Résumé
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75 - VALLEE (I), TAIT (SWG) & POWELL (PP) - 2001 - African swine fever virus infection of porcine aortic endothelial cells leads to inhibition of inflammatory responses, activation of the thrombotic state, and apoptosis. Journal of Virology, 75 (21): pp. 10372-10382. Résumé
76 - ZSAK (L), CALER (E), LU (Z), KUTISH (GF), NEILAND (JG) & ROCK (DL) - 1998 - A nonessential African swine fever virus gene UK is a significant virulence determinant in domestic swine. Journal of Virology, 1998 Feb; 72 (2): pp. 1028-1035. Résumé