|HEAD||PREVOST, Marie-Christine / firstname.lastname@example.org|
|MEMBERS||Dr. BONNE Isabelle / CAYET, Nadège / GUADAGNINI, Stéphanie / J. LO / Dr. LOUSSERT, Céline / MALLET, Adeline / PEHAU-ARNAUDET, Gérard / Dr. SACHSE, Martin / SCHMITT, Christine / DR. SARTORI Anna / VILEY, Christine
The work in the platform for ultrastructural microscopy (PFMU) consists of high resolution ultrastructural analysis aimed at answering scientific questions in collaboration with departments of the Pasteur Institute and with other research establishments such as: INSERM, CNRS, laboratories from different Universities, Curie Institute, Necker Hospital, National Center of Reference and the International network of Pasteur Institutes.
Within these projects, new approaches and technologies are implemented or developed to obtain the best performances when answering to specific questions.
The morphological expertise of the platform lies in the following areas :
In addition, the PFMU offers service activities for rapid diagnosis of agents responsible for new emerging diseases.
Within the institute, the PFMU offers training sessions for users to become autonomous in sample preparation as well as in the samples analysis.
Outside the institute, the PFMU participates in the organization of workshops for a wider audience as :
Keywords: Scanning and Transmission Electron Microscopy (SEM AND TEM), Ultrastructure, Immunolabeling, Cryosectioning, Cryofixation, Cryomicroscopy, CEMOVIS, Correlative Light/Electron Microscopoy
Beauvais A, Schmidt C, Guadagnisi S, Roux P, Perret E, Henry C, Paris S, Mallet A, Prevost MC, Latgé JP (2007). An extracellular matrix glues together the aerial grown hyphae of Aspergillus fumigatus. Cell Microbiol. 9:1588-600.
Couderc, T, Chrétien F, Shilte C, Disson O., Brigitte M, Guivel-Benhassine F, Touret Y, Barau G, Cayet N, Schuffenecker I, Desprès P, Arenzana-Seisdedos F, Michault A, Albert M L , Lecuit M.« A mouse Model for chikungunya: Young Age and Inefficient Type-I Interferon signaling are risk factors for severe disease » PloS Pathogens, February 2008, Vol 4, Issue 2.
Amino R, Giovannini D, Thiberge S, Gueirard P, Boisson B, Dubremets JF, Prévost MC, Ishino T, Yuda M and Ménard R. « Host cell traversal is important for progression of the malaria parasite through the dermis to the liver » Cell Host & Microbe 3, February 2008, pp. 88-96
Goyard S, Knechtle P, Chauvel M, Mallet A, Prévost MC, Proux C, Coppée JY, Schwartz P, Dromer F, Park H, Filler SG, Janbon G and d’Enfert C. «The Yak1 Kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans» Molecular Biology of the Cell, Vol 19, pp 2251-2266, May 2008
Galy V, Antonin W, Jaedicke A, Sachse M, Santarella R, Haselmann U and Mattaj L. « A role for gp210 in mitotic nuclear-envelope breakdown » Cell Science 121, 317-328 Published by The Company of Biologists 2008
Activity Reports 2009 - Institut Pasteur
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